Search Results - "de Keczer"

An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity by Liu, Hong-Hsing, Lu, Peng, Guo, Yingying, Farrell, Erin, Zhang, Xun, Zheng, Ming, Bosano, Betty, Zhang, Zhaomei, Allard, John, Liao, Guochun, Fu, Siyu, Chen, Jinzhi, Dolim, Kimberly, Kuroda, Ayako, Usuka, Jonathan, Cheng, Janet, Tao, William, Welch, Kevin, Liu, Yanzhou, Pease, Joseph, de Keczer, Steve A, Masjedizadeh, Mohammad, Hu, Jing-Shan, Weller, Paul, Garrow, Tim, Peltz, Gary

“…Acetaminophen-induced liver toxicity is the most frequent precipitating cause of acute liver failure and liver transplant, but contemporary medical practice…”
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5‐Hydroxytryptamine (5‐HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases by Reynolds, G.P., Mason, S.L., Meldrum, A., Keczer, S., Parties, H., Eglen, R.M., Wong, E.H.F.

“…1 The distribution, pharmacology and effects of neurodegenerative diseases on 5‐HT4 receptors in human brain have been characterized in vitro. 2 The 5‐HT4…”
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Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: Synthesis and optimization studies of benzothiazine-substituted tetramic acids by de Vicente, Javier, Hendricks, Robert T., Smith, David B., Fell, Jay B., Fischer, John, Spencer, Stacey R., Stengel, Peter J., Mohr, Peter, Robinson, John E., Blake, James F., Hilgenkamp, Ramona K., Yee, Calvin, Zhao, Junping, Elworthy, Todd R., Tracy, Jahari, Chin, Elbert, Li, Jim, Lui, Al, Wang, Beihan, Oshiro, Connie, Harris, Seth F., Ghate, Manjiri, Leveque, Vincent J.P., Najera, Isabel, Pogam, Sophie Le, Rajyaguru, Sonal, Ao-Ieong, Gloria, Alexandrova, Ludmila, Fitch, Bill, Brandl, Michael, Masjedizadeh, Mohammad, Wu, Shao-yong, Keczer, Steve de, Voronin, Tatyana

“…Benzothiazine-substituted tetramic acids were discovered as highly potent non-nucleoside inhibitors of HCV NS5B polymerase. X-ray crystallography studies…”
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Quantification of DNA Using the Luminescent Oxygen Channeling Assay by Patel, Rajesh, Pollner, Reinhold, de Keczer, Steve, Pease, John, Pirio, Marcel, DeChene, Neal, Dafforn, Alan, Rose, Sam

“…Simplified and cost-effective methods for the detection and quantification of nucleic acid targets are still a challenge in molecular diagnostics. Luminescent…”
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Homogeneous, rapid luminescent oxygen channeling immunoassay (LOCI(TM)) for homocysteine by Liu, YP, de Keczer S, Alexander, S, Pirio, M, Davalian, D, Kurn, N, Ullman, EF

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Simple single-step single-enzyme synthesis of [14C]-GSH by de Keczer, Steve A., Voronin, Tatyana, Yao, Jennifer, Zhang, Fang-Jie, Masjedizadeh, Mohammad R.

“…The tri‐peptide [14C]‐glutathione ([14C]‐GSH) was synthesized in a single step by GSH synthetase catalyzed reaction of L‐γ‐glutamyl‐L‐cysteine and…”
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Adsorption losses from urine-based cannabinoid calibrators during routine use by Blanc, J A, Manneh, V A, Ernst, R, Berger, D E, de Keczer, S A, Chase, C, Centofanti, J M, DeLizza, A J

“…The major metabolite of cannabis found in urine, 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (delta 9-THC), is the compound most often used to…”
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High specific activity tritium labeling of vitamin D derivative RO275646 by de Keczer, Steve A., Lane, Tim S., Voronin, Tatyana, Masjedizadeh, Mohammad R.

“…The octahydroindenone intermediate was tritium labeled using T2O isotope exchange labeling, and then elaborated to the vitamin D derivative RO275646. Though…”
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M+4 stable isotope labeling of levovirin and M+7 and carbon-14 labeling of levovirin valinate pro-drug by de Keczer, Steve A., Masjedizadeh, Mohammad R., Wu, Shao-Yong, Lara-Jaime, Teresa, Comstock, Kate, Dvorak, Charles, Liu, Yu-Ying, Berger, Walter

“…[M+4]‐labeled levovirin 5 (231 mg) was synthesized as an MS reference compound from [M+4] triazole ester 2. [M+7]‐labeled levovirin valinate 6 (127 mg) was…”
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Uncatalyzed microwave deuterium exchange labeling of bleomycin A2 by de Keczer, Steve A., Lane, Tim S., Masjedizadeh, Mohammad R.

“…Bleomycin sulfate in D2O was deuterated using microwave irradiation under catalyst free conditions. Following the removal of labile deuterium and purification,…”
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Uncatalyzed microwave deuterium exchange labeling of bleomycin A 2 by de Keczer, Steve A., Lane, Tim S., Masjedizadeh, Mohammad R.

“…Bleomycin sulfate in D 2 O was deuterated using microwave irradiation under catalyst free conditions. Following the removal of labile deuterium and…”
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Intestinal absorption, distribution and excretion of an orally administered polymeric antioxidant in rats and mice by Parkinson, T M, Honohan, T, Enderlin, F E, Halladay, S C, Hale, R L, de Keczer, Dubin, P L, Ryerson, B A, Read, A R

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