Search Results - "de Juan Pardo, Elena"
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Biologically Inspired Scaffolds for Heart Valve Tissue Engineering via Melt Electrowriting
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2019)“…Heart valves are characterized to be highly flexible yet tough, and exhibit complex deformation characteristics such as nonlinearity, anisotropy, and…”
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2
Melt Electrospinning Writing of Highly Ordered Large Volume Scaffold Architectures
Published in Advanced materials (Weinheim) (17-05-2018)“…The additive manufacturing of highly ordered, micrometer‐scale scaffolds is at the forefront of tissue engineering and regenerative medicine research. The…”
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3
The Technological Advancement to Engineer Next‐Generation Stent‐Grafts: Design, Material, and Fabrication Techniques
Published in Advanced healthcare materials (01-07-2022)“…Endovascular treatment of aortic disorders has gained wide acceptance due to reduced physiological burden to the patient compared to open surgery, and ongoing…”
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4
The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells
Published in Cancer research (Chicago, Ill.) (15-05-2009)“…Glioblastoma multiforme (GBM) is a malignant astrocytoma of the central nervous system associated with a median survival time of 15 months, even with…”
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Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells
Published in Stem cells (Dayton, Ohio) (01-11-2011)“…Adult neural stem cells (NSCs) play important roles in learning and memory and are negatively impacted by neurological disease. It is known that biochemical…”
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Semi‐Woven Structures via Dual Nozzle Melt Electrowriting
Published in Macromolecular materials and engineering (01-04-2023)“…Melt electrowriting is an additive manufacturing technique utilizing electrohydrodynamic forces to create nano‐ to micro‐scale fibrous polymer objects. It is a…”
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7
A Growth Factor-Free Co-Culture System of Osteoblasts and Peripheral Blood Mononuclear Cells for the Evaluation of the Osteogenesis Potential of Melt-Electrowritten Polycaprolactone Scaffolds
Published in International journal of molecular sciences (01-03-2019)“…Scaffolds made of biodegradable biomaterials are widely used to guide bone regeneration. Commonly, in vitro assessment of scaffolds' osteogenesis potential has…”
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Engineering Heart Valve Interfaces Using Melt Electrowriting: Biomimetic Design Strategies from Multi‐Modal Imaging
Published in Advanced healthcare materials (01-12-2022)“…Interfaces within biological tissues not only connect different regions but also contribute to the overall functionality of the tissue. This is especially true…”
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Tissue engineering of corneal stroma via melt electrowriting
Published in Journal of tissue engineering and regenerative medicine (01-10-2021)“…The cornea serves as the main refractive component of the eye with the corneal stroma constituting the thickest component in a stratified layered system of…”
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10
Role of substrate biomechanics in controlling (stem) cell fate: Implications in regenerative medicine
Published in Journal of tissue engineering and regenerative medicine (01-04-2018)“…Tissue‐specific stem cells reside in a specialized environment known as niche. The niche plays a central role in the regulation of cell behaviour and, through…”
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11
Free Form Deformation-Based Image Registration Improves Accuracy of Traction Force Microscopy
Published in PloS one (07-12-2015)“…Traction Force Microscopy (TFM) is a widespread method used to recover cellular tractions from the deformation that they cause in their surrounding substrate…”
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Image analysis for the quantitative comparison of stress fibers and focal adhesions
Published in PloS one (30-09-2014)“…Actin stress fibers (SFs) detect and transmit forces to the extracellular matrix through focal adhesions (FAs), and molecules in this pathway determine…”
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13
Periosteum‐derived mesenchymal progenitor cells in engineered implants promote fracture healing in a critical‐size defect rat model
Published in Journal of tissue engineering and regenerative medicine (01-05-2019)“…An attractive alternative to bone autografts is the use of autologous mesenchymal progenitor cells (MSCs) in combination with biomaterials. We compared the…”
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Spatially Heterogeneous Tubular Scaffolds for In Situ Heart Valve Tissue Engineering Using Melt Electrowriting
Published in Advanced functional materials (01-05-2022)“…Heart valve tissue engineering (HVTE) aims to provide living autologous heart valve implants endowed with regenerative capabilities and life‐long durability…”
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Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study
Published in International journal of cancer (15-09-2018)“…Despite significant advances, most current in vivo models fail to fully recapitulate the biological processes that occur in humans. Here we aimed to develop an…”
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Natural, synthetic and commercially-available biopolymers used to regenerate tendons and ligaments
Published in Bioactive materials (01-01-2023)“…Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a significant role in TL tissue repair, whether the treatment relies on…”
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Understanding the Significance of Layer Bonding in Melt Electrowriting
Published in Advanced science (24-10-2024)“…Melt electrowriting (MEW) is a high-resolution additive manufacturing technology capable of depositing micrometric fibers onto a moving collector to form 3D…”
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Melt Electrowriting of Complex 3D Anatomically Relevant Scaffolds
Published in Frontiers in bioengineering and biotechnology (24-07-2020)“…The manufacture of fibrous scaffolds with tailored micrometric features and anatomically relevant three-dimensional (3D) geometries for soft tissue engineering…”
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Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone
Published in Science translational medicine (01-08-2018)“…Intravital multiphoton microscopy (iMPM) in mice provides access to cellular and molecular mechanisms of metastatic progression of cancers and the underlying…”
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Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications
Published in Journal of visualized experiments (23-12-2017)“…This tutorial reflects on the fundamental principles and guidelines for electrospinning writing with polymer melts, an additive manufacturing technology with…”
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