Search Results - "de Jong, Nico"
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Acoustic behavior of microbubbles and implications for drug delivery
Published in Advanced drug delivery reviews (01-06-2014)“…Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they increasingly show potential for drug delivery. This review focuses on the…”
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2
Stability of Monodisperse Phospholipid-Coated Microbubbles Formed by Flow-Focusing at High Production Rates
Published in Langmuir (26-04-2016)“…Monodisperse microbubble ultrasound contrast agents may dramatically increase the sensitivity and efficiency in ultrasound imaging and therapy. They can be…”
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3
Laser-driven resonance of dye-doped oil-coated microbubbles: A theoretical and numerical study
Published in The Journal of the Acoustical Society of America (01-04-2017)“…Microbubbles are used to enhance the contrast in ultrasound imaging. When coated with an optically absorbing material, these bubbles can also provide contrast…”
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4
Frequency Analysis of the Photoacoustic Signal Generated by Coronary Atherosclerotic Plaque
Published in Ultrasound in medicine & biology (01-08-2016)“…Abstract The identification of unstable atherosclerotic plaques in the coronary arteries is emerging as an important tool for guiding percutaneous coronary…”
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Development of a Stationary 3D Photoacoustic Imaging System Using Sparse Single-Element Transducers: Phantom Study
Published in Applied sciences (01-11-2019)“…Photoacoustic imaging (PAI) is an emerging label-free and non-invasive modality for imaging biological tissues. PAI has been implemented in different…”
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Brandaris 128 ultra-high-speed imaging facility: 10 years of operation, updates, and enhanced features
Published in Review of scientific instruments (01-10-2012)“…The Brandaris 128 ultra-high-speed imaging facility has been updated over the last 10 years through modifications made to the camera's hardware and software…”
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7
Theranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy
Published in Pharmaceutics (28-01-2022)“…Phospholipid-coated targeted microbubbles are used for ultrasound molecular imaging and locally enhanced drug delivery, with the binding efficacy being an…”
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Uniform scattering and attenuation of acoustically sorted ultrasound contrast agents: Modeling and experiments
Published in The Journal of the Acoustical Society of America (01-10-2016)“…The sensitivity and efficiency in contrast-enhanced ultrasound imaging and therapy can potentially be increased by the use of resonant monodisperse bubbles…”
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9
Microbubble characterization through acoustically induced deflation
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-01-2010)“…Ultrasound contrast agents (UCA) populations are typically polydisperse and contain microbubbles with radii over a given range. Although the behavior of…”
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10
Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis
Published in Journal of controlled release (10-01-2015)“…Although promising results are achieved in ultrasound mediated drug delivery, its underlying biophysical mechanisms remain to be elucidated. Pore formation as…”
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11
Are monodisperse phospholipid-coated microbubbles “mono-acoustic?”
Published in Applied physics letters (03-06-2024)“…Phospholipid-coated microbubbles with a uniform acoustic response are a promising avenue for functional ultrasound sensing. A uniform acoustic response…”
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12
Acoustic droplet vaporization is initiated by superharmonic focusing
Published in Proceedings of the National Academy of Sciences - PNAS (04-02-2014)“…Acoustically sensitive emulsion droplets composed of a liquid perfluorocarbon have the potential to be a highly efficient system for local drug delivery,…”
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13
Opening of endothelial cell–cell contacts due to sonoporation
Published in Journal of controlled release (10-06-2020)“…Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic…”
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14
Sonoporation from Jetting Cavitation Bubbles
Published in Biophysical journal (01-12-2006)“…The fluid dynamic interaction of cavitation bubbles with adherent cells on a substrate is experimentally investigated. We find that the nonspherical collapse…”
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Detection of Contrast Agents: Plane Wave Versus Focused Transmission
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-02-2016)“…Ultrasound contrast agent (UCA) imaging provides a cost-effective diagnostic tool to assess tissue perfusion and vascular pathologies. However, excessive…”
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16
Compressive 3D ultrasound imaging using a single sensor
Published in Science advances (01-12-2017)“…Three-dimensional ultrasound is a powerful imaging technique, but it requires thousands of sensors and complex hardware. Very recently, the discovery of…”
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17
Characterization of Definity™ Ultrasound Contrast Agent at Frequency Range of 5–15 MHz
Published in Ultrasound in medicine & biology (01-02-2011)“…Abstract The status of vasa vasorum, which can be imaged using ultrasound contrast agents, is an indication for the progression of atherosclerosis. The…”
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Viability of endothelial cells after ultrasound-mediated sonoporation: Influence of targeting, oscillation, and displacement of microbubbles
Published in Journal of controlled release (28-09-2016)“…Microbubbles (MBs) have been shown to create transient or lethal pores in cell membranes under the influence of ultrasound, known as ultrasound-mediated…”
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4-D Echo-Particle Image Velocimetry in a Left Ventricular Phantom
Published in Ultrasound in medicine & biology (01-03-2020)“…Left ventricular (LV) blood flow is an inherently complex time-varying 3-D phenomenon, where 2-D quantification often ignores the effect of out-of-plane…”
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Comparison of Phase-Screen and Geometry-Based Phase Aberration Correction Techniques for Real-Time Transcranial Ultrasound Imaging
Published in Applied sciences (01-10-2022)“…While transcranial ultrasound imaging is a promising diagnostic modality, it is still hindered due to phase aberration and multiple scattering caused by the…”
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