Search Results - "de Jong, Eiko K"

Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration by Cipriani, Valentina, Lorés-Motta, Laura, He, Fan, Fathalla, Dina, Tilakaratna, Viranga, McHarg, Selina, Bayatti, Nadhim, Acar, İlhan E., Hoyng, Carel B., Fauser, Sascha, Moore, Anthony T., Yates, John R. W., de Jong, Eiko K., Morgan, B. Paul, den Hollander, Anneke I., Bishop, Paul N., Clark, Simon J.

“…Age-related macular degeneration (AMD) is a leading cause of blindness. Genetic variants at the chromosome 1q31.3 encompassing the complement factor H ( CFH ,…”
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Epigenetic regulation of learning and memory by Drosophila EHMT/G9a by Kramer, Jamie M, Kochinke, Korinna, Oortveld, Merel A W, Marks, Hendrik, Kramer, Daniela, de Jong, Eiko K, Asztalos, Zoltan, Westwood, J Timothy, Stunnenberg, Hendrik G, Sokolowski, Marla B, Keleman, Krystyna, Zhou, Huiqing, van Bokhoven, Hans, Schenck, Annette

“…The epigenetic modification of chromatin structure and its effect on complex neuronal processes like learning and memory is an emerging field in neuroscience…”
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Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration by Heesterbeek, Thomas J., de Jong, Eiko K., Acar, Ilhan E., Groenewoud, Joannes M. M., Liefers, Bart, Sánchez, Clara I., Peto, Tunde, Hoyng, Carel B., Pauleikhoff, Daniel, Hense, Hans W., den Hollander, Anneke I.

“…Several prediction models for progression of age-related macular degeneration (AMD) have been developed, but the added value of using genetic information in…”
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Hyperreflective foci on optical coherence tomography associate with treatment outcome for anti-VEGF in patients with diabetic macular edema by Schreur, Vivian, Altay, Lebriz, van Asten, Freekje, Groenewoud, Joannes M M, Fauser, Sascha, Klevering, B Jeroen, Hoyng, Carel B, de Jong, Eiko K

“…To investigate the relationship between baseline number of hyperreflective foci (HF) on spectral domain optical coherence tomography (SD-OCT) in patients with…”
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OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy by Teussink, Michel M, Breukink, Myrte B, van Grinsven, Mark J J P, Hoyng, Carel B, Klevering, B Jeroen, Boon, Camiel J F, de Jong, Eiko K, Theelen, Thomas

“…Abnormal choroidal blood flow is considered important in the pathogenesis of chronic central serous chorioretinopathy (CSC). Optical coherence tomography (OCT)…”
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Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration by Kersten, Eveline, MSc, Paun, Constantin C., MSc, Schellevis, Rosa L., MSc, Hoyng, Carel. B., PhD, Delcourt, Cécile, PhD, Lengyel, Imre, PhD, Peto, Tunde, PhD, Ueffing, Marius, PhD, Klaver, Caroline C.W., PhD, Dammeier, Sascha, PhD, den Hollander, Anneke I., PhD, de Jong, Eiko K., PhD

“…Abstract Biomarkers can help unravel mechanisms of disease and identify new targets for therapy. They can also be useful in clinical practice for monitoring…”
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Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy by Schreur, Vivian, Brouwers, Jody, Huet, Ramon A.C., Smeets, Sandra, Phan, Milan, Hoyng, Carel B., Jong, Eiko K., Klevering, B. Jeroen

“…Purpose To investigate the long‐term outcomes of patients who underwent vitrectomy for proliferative diabetic retinopathy. Methods Cumulative incidences were…”
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Chronic Central Serous Chorioretinopathy Is Associated with Genetic Variants Implicated in Age-Related Macular Degeneration by de Jong, Eiko K., PhD, Breukink, Myrte B., MD, Schellevis, Rosa L., MSc, Bakker, Bjorn, BSc, Mohr, Jacqueline K., MD, Fauser, Sascha, MD, PhD, Keunen, Jan E.E., MD, PhD, Hoyng, Carel B., MD, PhD, den Hollander, Anneke I., PhD, Boon, Camiel J.F., MD, PhD

“…Purpose In this study, single nucleotide polymorphisms (SNPs) at 19 loci, previously associated with age-related macular degeneration (AMD), were…”
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Correlation between redefined optical coherence tomography parameters and best-corrected visual acuity in non-resolving central serous chorioretinopathy treated with half-dose photodynamic therapy by van Rijssen, Thomas J, Mohabati, Danial, Dijkman, Greet, Theelen, Thomas, de Jong, Eiko K, van Dijk, Elon H C, Boon, Camiel J F

“…To assess parameters on optical coherence tomography (OCT), and their correlation with best-corrected visual acuity (BCVA) in patients with non-resolving…”
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GENETIC RISK FACTORS IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY by Mohabati, Danial, Schellevis, Rosa L, van Dijk, Elon H C, Altay, Lebriz, Fauser, Sascha, Hoyng, Carel B, De Jong, Eiko K, Boon, Camiel J F, Yzer, Suzanne

“…To investigate genetic associations in white patients with acute central serous chorioretinopathy (aCSC) and to assess genetic differences between aCSC and…”
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Exome sequencing in patients with chronic central serous chorioretinopathy by Schellevis, Rosa L., Breukink, Myrte B., Gilissen, Christian, Boon, Camiel J. F., Hoyng, Carel B., de Jong, Eiko K., den Hollander, Anneke I.

“…Chronic central serous chorioretinopathy (cCSC) is a multifactorial eye disease characterized by subretinal fluid accumulation that leads to vision loss…”
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Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes by Porter, Louise F, Saptarshi, Neil, Fang, Yongxiang, Rathi, Sonika, den Hollander, Anneke I, de Jong, Eiko K, Clark, Simon J, Bishop, Paul N, Olsen, Timothy W, Liloglou, Triantafillos, Chavali, Venkata R M, Paraoan, Luminita

“…Age-related macular degeneration (AMD) is a degenerative disorder of the central retina and the foremost cause of blindness. The retinal pigment epithelium…”
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Exploring the Use of Molecular Biomarkers for Precision Medicine in Age-Related Macular Degeneration by Lorés-Motta, Laura, de Jong, Eiko K., den Hollander, Anneke I.

“…Precision medicine aims to improve patient care by adjusting medication to each patient’s individual needs. Age-related macular degeneration (AMD) is a…”
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Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels by Ristau, Tina, Paun, Constantin, Ersoy, Lebriz, Hahn, Moritz, Lechanteur, Yara, Hoyng, Carel, de Jong, Eiko K, Daha, Mohamed R, Kirchhof, Bernd, den Hollander, Anneke I, Fauser, Sascha

“…Age-related macular degeneration (AMD) is a common condition that leads to severe vision loss and dysregulation of the complement system is thought to be…”
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The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Model to Study Central Serous Chorioretinopathy by Brinks, Joost, van Dijk, Elon H C, Habeeb, Mahmoud, Nikolaou, Aikaterini, Tsonaka, Roula, Peters, Hendrika A B, Sips, Hetty C M, van de Merbel, Arjanneke F, de Jong, Eiko K, Notenboom, Robbert G E, Kielbasa, Szymon M, van der Maarel, Silvère M, Quax, Paul H A, Meijer, Onno C, Boon, Camiel J F

“…To isolate, culture, and characterize primary human choroidal endothelial cells, and to assess their responsiveness to corticosteroids, in order to enable…”
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CNTNAP2 and NRXN1 Are Mutated in Autosomal-Recessive Pitt-Hopkins-like Mental Retardation and Determine the Level of a Common Synaptic Protein in Drosophila by Zweier, Christiane, de Jong, Eiko K., Zweier, Markus, Orrico, Alfredo, Ousager, Lilian B., Collins, Amanda L., Bijlsma, Emilia K., Oortveld, Merel A.W., Ekici, Arif B., Reis, André, Schenck, Annette, Rauch, Anita

“…Heterozygous copy-number variants and SNPs of CNTNAP2 and NRXN1, two distantly related members of the neurexin superfamily, have been repeatedly associated…”
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Whole Exome Sequencing in Patients with the Cuticular Drusen Subtype of Age-Related Macular Degeneration by Duvvari, Maheswara R, van de Ven, Johannes P H, Geerlings, Maartje J, Saksens, Nicole T M, Bakker, Bjorn, Henkes, Arjen, Neveling, Kornelia, del Rosario, Marisol, Westra, Dineke, van den Heuvel, Lambertus P W J, Schick, Tina, Fauser, Sascha, Boon, Camiel J F, Hoyng, Carel B, de Jong, Eiko K, den Hollander, Anneke I

“…Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in elderly people worldwide. Cuticular drusen (CD) is a clinical subtype…”
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Systemic complement activation in central serous chorioretinopathy by van Dijk, Elon H C, Tsonaka, Roula, Klar-Mohamad, Ngaisah, Wouters, Diana, de Vries, Aiko P J, de Jong, Eiko K, van Kooten, Cees, Boon, Camiel J F

“…A clear link between several variants in genes involved in the complement system and chronic central serous chorioretinopathy (CSC) has been described. In…”
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Clinical spectrum of severe chronic central serous chorioretinopathy and outcome of photodynamic therapy by Mohabati, Danial, van Dijk, Elon Hc, van Rijssen, Thomas J, de Jong, Eiko K, Breukink, Myrte B, Martinez-Ciriano, Jose P, Dijkman, Greet, Hoyng, Carel B, Fauser, Sascha, Yzer, Suzanne, Boon, Camiel Jf

“…To describe a spectrum of severe chronic central serous chorioretinopathy (cCSC) cases and their response to photodynamic therapy (PDT). A total of 66 patients…”
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Vesicle-Mediated Transport and Release of CCL21 in Endangered Neurons: A Possible Explanation for Microglia Activation Remote from a Primary Lesion by de Jong, Eiko K, Dijkstra, Ineke M, Hensens, Marjolein, Brouwer, Nieske, van Amerongen, Machteld, Liem, Robert S. B, Boddeke, Hendrikus W. G. M, Biber, Knut

“…Whenever neurons in the CNS are injured, microglia become activated. In addition to local activation, microglia remote from the primary lesion site are…”
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