Search Results - "de Jong, Ebbing"

Salivary proteomics of healthy dogs: An in depth catalog by Torres, Sheila M F, Furrow, Eva, Souza, Clarissa P, Granick, Jennifer L, de Jong, Ebbing P, Griffin, Timothy J, Wang, Xiong

“…To provide an in-depth catalog of the salivary proteome and endogenous peptidome of healthy dogs, evaluate proteins and peptides with antimicrobial properties,…”
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Mitochondrial protein import clogging as a mechanism of disease by Coyne, Liam P, Wang, Xiaowen, Song, Jiyao, de Jong, Ebbing, Schneider, Karin, Massa, Paul T, Middleton, Frank A, Becker, Thomas, Chen, Xin Jie

“…Mitochondrial biogenesis requires the import of >1,000 mitochondrial preproteins from the cytosol. Most studies on mitochondrial protein import are focused on…”
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Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis by Pedicone, Chiara, Fernandes, Sandra, Dungan, Otto M, Dormann, Shawn M, Viernes, Dennis R, Adhikari, Arijit A, Choi, Lydia B, De Jong, Ebbing P, Chisholm, John D, Kerr, William G

“…We show here that both SHIP1 ( ) and its paralog SHIP2 ( 1) are expressed at protein level in microglia. To examine whether targeting of SHIP paralogs might…”
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Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome by Sun, Jiao, Kim, Jin-Young, Jun, Semo, Park, Meeyeon, de Jong, Ebbing, Chang, Jae-Woong, Cheng, Sze, Fan, Deliang, Chen, Yue, Griffin, Timothy J., Lee, Jung-Hee, You, Ho Jin, Zhang, Wei, Yong, Jeongsik

“…Alternative cleavage and polyadenylation within introns (intronic APA) generate shorter mRNA isoforms; however, their physiological significance remains…”
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Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesions by de Jong, Ebbing P, Xie, Hongwei, Onsongo, Getiria, Stone, Matthew D, Chen, Xiao-Bing, Kooren, Joel A, Refsland, Eric W, Griffin, Robert J, Ondrey, Frank G, Wu, Baolin, Le, Chap T, Rhodus, Nelson L, Carlis, John V, Griffin, Timothy J

“…Oral cancer survival rates increase significantly when it is detected and treated early. Unfortunately, clinicians now lack tests which easily and reliably…”
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Mass spectrometry-based proteomics: basic principles and emerging technologies and directions by Van Riper, Susan K, de Jong, Ebbing P, Carlis, John V, Griffin, Timothy J

“…As the main catalytic and structural molecules within living systems, proteins are the most likely biomolecules to be affected by radiation exposure…”
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Proteomics Analysis of Cells in Whole Saliva from Oral Cancer Patients via Value-added Three-dimensional Peptide Fractionation and Tandem Mass Spectrometry by Xie, Hongwei, Onsongo, Getiria, Popko, Jonathan, de Jong, Ebbing P., Cao, Jing, Carlis, John V., Griffin, Robert J., Rhodus, Nelson L., Griffin, Timothy J.

“…Whole human saliva possesses tremendous potential in clinical diagnostics, particularly for conditions within the oral cavity such as oral cancer. Although…”
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Sample collection and handling considerations for peptidomic studies in whole saliva; implications for biomarker discovery by de Jong, Ebbing P., van Riper, Susan K., Koopmeiners, Joseph S., Carlis, John V., Griffin, Timothy J.

“…Proteomic studies in saliva have demonstrated its potential as a diagnostic biofluid, however the salivary peptidome is less studied. Here we study the effects…”
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Purification of human β- and γ-actin from budding yeast by Haarer, Brian K, Pimm, Morgan L, de Jong, Ebbing P, Amberg, David C, Henty-Ridilla, Jessica L

“…Biochemical studies of human actin and its binding partners rely heavily on abundant and easily purified α-actin from skeletal muscle. Therefore, muscle actin…”
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A comparative analysis of paxillin and Hic-5 proximity interactomes by Brock, Katia, Alpha, Kyle M, Brennan, Grant, De Jong, Ebbing P, Luke, Elizabeth, Turner, Christopher E

“…Focal adhesions serve as structural and signaling hubs, facilitating bidirectional communication at the cell-extracellular matrix interface. Paxillin and the…”
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mRNA 3′-UTR shortening is a molecular signature of mTORC1 activation by Chang, Jae-Woong, Zhang, Wei, Yeh, Hsin-Sung, de Jong, Ebbing P., Jun, Semo, Kim, Kwan-Hyun, Bae, Sun S., Beckman, Kenneth, Hwang, Tae Hyun, Kim, Kye-Seong, Kim, Do-Hyung, Griffin, Timothy J., Kuang, Rui, Yong, Jeongsik

“…Mammalian target of rapamycin (mTOR) enhances translation from a subset of messenger RNAs containing distinct 5′-untranslated region (UTR) sequence features…”
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Online Nanoscale ERLIC-MS Outperforms RPLC–MS for Shotgun Proteomics in Complex Mixtures by de Jong, Ebbing P, Griffin, Timothy J

“…We have explored the use of electrostatic repulsion hydrophilic interaction chromatography (ERLIC) as an alternative to the gold-standard in shotgun…”
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Improved Intensity-Based Label-Free Quantification via Proximity-Based Intensity Normalization (PIN) by Van Riper, Susan K, de Jong, Ebbing P, Higgins, LeeAnn, Carlis, John V, Griffin, Timothy J

“…Researchers are increasingly turning to label-free MS1 intensity-based quantification strategies within HPLC–ESI–MS/MS workflows to reveal biological variation…”
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Spectral filtering of light-emitting diodes for fluorescence detection by de Jong, Ebbing P., Lucy, Charles A.

“…The use of light-emitting diodes (LEDs) for fluorescence detection has recently gained much interest. The broad wavelength emission of LEDs requires spectral…”
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Noncovalent labeling of myoglobin for capillary electrophoresis with laser-induced fluorescence detection by reconstitution with a fluorescent porphyrin by de Jong, Ebbing P., Melanson, Jeremy E., Lucy, Charles A.

“…Traditional protein labeling reactions for capillary electrophoresis (CE) with laser‐induced fluorescence (LIF) detection suffer from a variety of…”
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Developing Photoaffinity Probes for Dopamine Receptor D2 to Determine Targets of Parkinson’s Disease Drugs by Kim, Spencer T., Doukmak, Emma J., Flax, Raymond G., Gray, Dylan J., Zirimu, Victoria N., de Jong, Ebbing, Steinhardt, Rachel C.

“…Dopaminergic pathways control highly consequential aspects of physiology and behavior. One of the most therapeutically important and best-studied receptors in…”
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Developing Photoaffinity Probes for Dopamine Receptor D 2 to Determine Targets of Parkinson's Disease Drugs by Kim, Spencer T, Doukmak, Emma J, Flax, Raymond G, Gray, Dylan J, Zirimu, Victoria N, de Jong, Ebbing, Steinhardt, Rachel C

“…Dopaminergic pathways control highly consequential aspects of physiology and behavior. One of the most therapeutically important and best-studied receptors in…”
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Salivary proteomics in bisphosphonate-related osteonecrosis of the jaw by Thumbigere-Math, V, Michalowicz, BS, de Jong, EP, Griffin, TJ, Basi, DL, Hughes, PJ, Tsai, ML, Swenson, KK, Rockwell, L, Gopalakrishnan, R

“…Objective The objective of this study was to identify differentially expressed salivary proteins in bisphosphonate‐related osteonecrosis of the jaw (BRONJ)…”
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Sample collection and handling considerations for peptidomics studies in whole saliva; implications for biomarker discovery by de Jong, Ebbing P., van Riper, Susan K., Koopmeiners, Joseph S., Carlis, John V., Griffin, Timothy J.

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An evaluation of the Noyori system “in reverse”: Thermodynamic and kinetic parameters of secondary alcohol transfer dehydrogenation catalyzed by [(η 6-1- i Pr-4-Me-C 6H 4)Ru(HN-CR′R″-CR′R″NTs)], R′ = H, Me; Ph, R″ = H, Me by Bierenstiel, Matthias, Dymarska, Magdalena, de Jong, Ebbing, Schlaf, Marcel

“…Even though it is an equilibrium reaction, “forward” and “reverse” are not the same in transfer hydrogenations catalyzed by the Noyori system! For a…”
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