Search Results - "de Jong, Arthur"

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons by Willems, Jelmer, de Jong, Arthur P H, Scheefhals, Nicky, Mertens, Eline, Catsburg, Lisa A E, Poorthuis, Rogier B, de Winter, Fred, Verhaagen, Joost, Meye, Frank J, MacGillavry, Harold D

“…The correct subcellular distribution of proteins establishes the complex morphology and function of neurons. Fluorescence microscopy techniques are invaluable…”
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RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes by de Jong, Arthur P.H., Roggero, Carlos M., Ho, Meng-Ru, Wong, Man Yan, Brautigam, Chad A., Rizo, Josep, Kaeser, Pascal S.

“…Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca2+ channels, and the presence of the phospholipid…”
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Doc2b Is a High-Affinity Ca²⁺ Sensor for Spontaneous Neurotransmitter Release by Groffen, Alexander J, Martens, Sascha, Arazola, Rocío Díez, Cornelisse, L. Niels, Lozovaya, Natalia, de Jong, Arthur P.H, Goriounova, Natalia A, Habets, Ron L.P, Takai, Yoshimi, Borst, J. Gerard, Brose, Nils, McMahon, Harvey T, Verhage, Matthijs

“…Synaptic vesicle fusion in brain synapses occurs in phases that are either tightly coupled to action potentials (synchronous), immediately following action…”
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Automated analysis of neuronal morphology, synapse number and synaptic recruitment by Schmitz, Sabine K., Hjorth, J.J. Johannes, Joemai, Raoul M.S., Wijntjes, Rick, Eijgenraam, Susanne, de Bruijn, Petra, Georgiou, Christina, de Jong, Arthur P.H., van Ooyen, Arjen, Verhage, Matthijs, Cornelisse, L. Niels, Toonen, Ruud F., Veldkamp, Wouter

“…[Display omitted] ▶ SynD reliably analyzes dendrite length and synapse number. ▶ SynD automatically quantifies dendritic branching and synaptic localization. ▶…”
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Integrated lab-on-chip biosensing systems based on magnetic particle actuation--a comprehensive review by van Reenen, Alexander, de Jong, Arthur M, den Toonder, Jaap M J, Prins, Menno W J

“…The demand for easy to use and cost effective medical technologies inspires scientists to develop innovative lab-on-chip technologies for point-of-care in…”
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Towards continuous monitoring of TNF-α at picomolar concentrations using biosensing by particle motion by Buskermolen, Alissa D., Michielsen, Claire M.S., de Jong, Arthur M., Prins, Menno W.J.

“…The ability to continuously monitor cytokines is desirable for fundamental research studies and healthcare applications. Cytokine release is characterized by…”
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Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability by Ruano, Dina, Abecasis, Gonçalo R., Glaser, Beate, Lips, Esther S., Cornelisse, L. Niels, de Jong, Arthur P.H., Evans, David M., Smith, George Davey, Timpson, Nicolas J., Smit, August B., Heutink, Peter, Verhage, Matthijs, Posthuma, Danielle

“…Although cognitive ability is a highly heritable complex trait, only a few genes have been identified, explaining relatively low proportions of the observed…”
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Presynaptic signal transduction pathways that modulate synaptic transmission by de Jong, Arthur PH, Verhage, Matthijs

“…Presynaptic modulation is a crucial factor in the adaptive capacity of the nervous system. The coupling between incoming action potentials and neurotransmitter…”
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Continuous biomarker monitoring with single molecule resolution by measuring free particle motion by Buskermolen, Alissa D., Lin, Yu-Ting, van Smeden, Laura, van Haaften, Rik B., Yan, Junhong, Sergelen, Khulan, de Jong, Arthur M., Prins, Menno W. J.

“…There is a need for sensing technologies that can continuously monitor concentration levels of critical biomolecules in applications such as patient care,…”
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SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse by Koopmans, Frank, van Nierop, Pim, Andres-Alonso, Maria, Byrnes, Andrea, Cijsouw, Tony, Coba, Marcelo P., Cornelisse, L. Niels, Farrell, Ryan J., Goldschmidt, Hana L., Howrigan, Daniel P., Hussain, Natasha K., Imig, Cordelia, de Jong, Arthur P.H., Jung, Hwajin, Kohansalnodehi, Mahdokht, Kramarz, Barbara, Lipstein, Noa, Lovering, Ruth C., MacGillavry, Harold, Mariano, Vittoria, Mi, Huaiyu, Ninov, Momchil, Osumi-Sutherland, David, Pielot, Rainer, Smalla, Karl-Heinz, Tang, Haiming, Tashman, Katherine, Toonen, Ruud F.G., Verpelli, Chiara, Reig-Viader, Rita, Watanabe, Kyoko, van Weering, Jan, Achsel, Tilmann, Ashrafi, Ghazaleh, Asi, Nimra, Brown, Tyler C., De Camilli, Pietro, Feuermann, Marc, Foulger, Rebecca E., Gaudet, Pascale, Joglekar, Anoushka, Kanellopoulos, Alexandros, Malenka, Robert, Nicoll, Roger A., Pulido, Camila, de Juan-Sanz, Jaime, Sheng, Morgan, Südhof, Thomas C., Tilgner, Hagen U., Bagni, Claudia, Bayés, Àlex, Biederer, Thomas, Brose, Nils, Chua, John Jia En, Dieterich, Daniela C., Gundelfinger, Eckart D., Hoogenraad, Casper, Huganir, Richard L., Jahn, Reinhard, Kaeser, Pascal S., Kim, Eunjoon, Kreutz, Michael R., McPherson, Peter S., Neale, Ben M., O’Connor, Vincent, Posthuma, Danielle, Ryan, Timothy A., Sala, Carlo, Feng, Guoping, Hyman, Steven E., Thomas, Paul D., Smit, August B., Verhage, Matthijs

“…Synapses are fundamental information-processing units of the brain, and synaptic dysregulation is central to many brain disorders (“synaptopathies”). However,…”
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Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR/Cas9 Gene Editing by Droogers, Wouter J, Willems, Jelmer, MacGillavry, Harold D, de Jong, Arthur P H

“…CRISPR/Cas9-mediated knock-in methods enable the labeling of individual endogenous proteins to faithfully determine their spatiotemporal distribution in cells…”
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Translating neuronal activity at the synapse: presynaptic calcium sensors in short-term plasticity by de Jong, Arthur P H, Fioravante, Diasynou

“…The complex manner in which patterns of presynaptic neural activity are translated into short-term plasticity (STP) suggests the existence of multiple…”
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Probing the Cell Membrane by Magnetic Particle Actuation and Euler Angle Tracking by Irmscher, Matthias, de Jong, Arthur M., Kress, Holger, Prins, Menno W.J.

“…The mechanical properties of the cell membrane and the subjacent actin cortex are determinants of a variety of processes in immunity and cell division. The…”
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Unusually high mechanical stability of bacterial adhesin extender domains having calcium clamps by Oude Vrielink, Anneloes S, Vance, Tyler D R, de Jong, Arthur M, Davies, Peter L, Voets, Ilja K

“…To gain insight into the relationship between protein structure and mechanical stability, single molecule force spectroscopy experiments on proteins with…”
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How Actuated Particles Effectively Capture Biomolecular Targets by van Reenen, Alexander, de Jong, Arthur M, Prins, Menno W. J

“…Because of their high surface-to-volume ratio and adaptable surface functionalization, particles are widely used in bioanalytical methods to capture molecular…”
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Protein kinase C is a calcium sensor for presynaptic short-term plasticity by Fioravante, Diasynou, Chu, YunXiang, de Jong, Arthur Ph, Leitges, Michael, Kaeser, Pascal S, Regehr, Wade G

“…In presynaptic boutons, calcium (Ca(2+)) triggers both neurotransmitter release and short-term synaptic plasticity. Whereas synaptotagmins are known to mediate…”
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RIM C 2 B Domains Target Presynaptic Active Zone Functions to PIP 2 -Containing Membranes by de Jong, Arthur P H, Roggero, Carlos M, Ho, Meng-Ru, Wong, Man Yan, Brautigam, Chad A, Rizo, Josep, Kaeser, Pascal S

“…Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca channels, and the presence of the phospholipid PIP…”
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Interparticle Capillary Forces at a Fluid–Fluid Interface with Strong Polymer-Induced Aging by Cappelli, Stefano, de Jong, Arthur M, Baudry, Jean, Prins, Menno W. J

“…We report on a measurement of forces between particles adsorbed at a water–oil interface in the presence of an oil-soluble polymer. The cationic polymer…”
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Dendritic position is a major determinant of presynaptic strength by de Jong, Arthur P H, Schmitz, Sabine K, Toonen, Ruud F G, Verhage, Matthijs

“…Different regulatory principles influence synaptic coupling between neurons, including positional principles. In dendrites of pyramidal neurons, postsynaptic…”
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Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity by de Jong, Arthur P. H., Meijer, Marieke, Saarloos, Ingrid, Cornelisse, Lennart Niels, Toonen, Ruud F. G., Sørensen, Jakob B., Verhage, Matthijs

“…Presynaptic activation of the diacylglycerol (DAG)/protein kinase C (PKC) pathway is a central event in short-term synaptic plasticity. Two substrates,…”
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