Search Results - "de Jong, Andrea E."
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Ustekinumab is associated with superior effectiveness outcomes compared to vedolizumab in Crohn’s disease patients with prior failure to anti‐TNF treatment
Published in Alimentary pharmacology & therapeutics (01-07-2020)“…Summary Background Both vedolizumab and ustekinumab can be considered for the treatment of Crohn’s disease (CD) when anti‐TNF treatment fails. However,…”
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Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry
Published in Alimentary pharmacology & therapeutics (01-05-2020)“…Summary Background Tofacitinib is a Janus kinase inhibitor approved for the treatment of ulcerative colitis (UC). Aim To evaluate effectiveness, safety and use…”
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Effectiveness and safety of tofacitinib for ulcerative colitis: two‐year results of the ICC Registry
Published in Alimentary pharmacology & therapeutics (01-01-2023)“…Summary Background Tofacitinib is an oral Janus kinase (JAK) inhibitor and is registered for the treatment of ulcerative colitis (UC). The effectiveness of…”
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Prior Colorectal Neoplasia Is Associated With Increased Risk of Ileoanal Pouch Neoplasia in Patients With Inflammatory Bowel Disease
Published in Gastroenterology (New York, N.Y. 1943) (2014)“…Background & Aims Although restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) substantially reduces the risk of colorectal cancer in patients…”
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Prognostic Value of the Modified Rutgeerts Score for Long-Term Outcomes After Primary Ileocecal Resection in Crohn's Disease
Published in The American journal of gastroenterology (01-02-2024)“…The prognostic value of the modified Rutgeerts score (mRS) in patients with Crohn's disease (CD) needs to be further elucidated. This study assessed the…”
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Prevalence of-and risk factors for work disability in Dutch patients with inflammatory bowel disease
Published in World journal of gastroenterology : WJG (14-12-2017)“…AIM To determine the prevalence of work disability in inflammatory bowel disease(IBD), and to assess risk factors associated with work disability.METHODS For…”
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One to 2-Year Surveillance Intervals Reduce Risk of Colorectal Cancer in Families With Lynch Syndrome
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2010)“…Background & Aims Two percent to 4% of all cases of colorectal cancer (CRC) are associated with Lynch syndrome. Dominant clustering of CRC (non-Lynch syndrome)…”
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Ustekinumab for Crohn’s Disease: Results of the ICC Registry, a Nationwide Prospective Observational Cohort Study
Published in Journal of Crohn's and colitis (01-01-2020)“…Abstract Background and Aims Ustekinumab is approved for the treatment of Crohn’s disease [CD]. Systematically registered prospective real-world data are…”
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Standardization of mesenchymal stromal cell therapy for perianal fistulizing Crohn’s disease
Published in European journal of gastroenterology & hepatology (01-10-2018)“…BACKGROUNDLocal administration of mesenchymal stromal cells (MSCs) into the fistula tract seems to improve patient outcome in perianal fistulas due to Crohn’s…”
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Smoking and colorectal neoplasia in patients with inflammatory bowel disease: Dose-effect relationship
Published in United European gastroenterology journal (01-09-2023)“…Prior studies on the effect of smoking on the risk of colitis-associated colorectal neoplasia (CRN) have reported conflicting results. We aimed to further…”
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Comparison of Patients’ and Doctors’ Reports on Health‐related Quality of Life in Celiac Disease
Published in Journal of pediatric gastroenterology and nutrition (01-05-2017)“…ABSTRACT Objective: To investigate whether implementation of a celiac disease (CD)–specific health‐related quality of life (HRQOL) questionnaire would add…”
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Illness Perceptions and Depression Are Associated with Health-Related Quality of Life in Youth with Inflammatory Bowel Disease
Published in International journal of behavioral medicine (01-08-2019)“…Background In youth with inflammatory bowel disease (IBD), health-related quality of life (HRQOL) has been shown to be affected by individual disease factors…”
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Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease
Published in Frontiers in immunology (23-06-2022)“…Chronic intestinal inflammation underlies inflammatory bowel disease (IBD). Previous studies indicated alterations in the cellular immune system; however, it…”
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Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets
Published in Immunity (Cambridge, Mass.) (17-05-2016)“…Inflammatory intestinal diseases are characterized by abnormal immune responses and affect distinct locations of the gastrointestinal tract. Although the role…”
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Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease
Published in BMJ open (01-11-2017)“…PurposeThe Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory…”
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Crohn's Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities
Published in Journal of clinical medicine (06-01-2023)“…Perianal fistulas are defined as pathological connections between the anorectal canal and the perianal skin. Most perianal fistulas are cryptoglandular…”
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Ustekinumab Trough Concentrations Are Associated with Biochemical Outcomes in Patients with Crohn’s Disease
Published in Digestive diseases and sciences (01-06-2023)“…Objective It is unknown whether ustekinumab (UST) levels can predict clinical outcomes in Crohn’s disease (CD) patients. We assessed the exposure–response…”
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Vedolizumab for Inflammatory Bowel Disease: Two-Year Results of the Initiative on Crohn and Colitis (ICC) Registry, A Nationwide Prospective Observational Cohort Study: ICC Registry - Vedolizumab
Published in Clinical pharmacology and therapeutics (01-05-2020)“…Prospective data of vedolizumab treatment for patients with inflammatory bowel disease (IBD) beyond 1 year of treatment is scarce but needed for clinical…”
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Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis
Published in JCI insight (08-05-2023)“…BACKGROUNDDue to their immunoregulatory and tissue regenerative features, mesenchymal stromal cells (MSCs) are a promising novel tool for the management of…”
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Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer
Published in PloS one (28-11-2012)“…There is an increasing demand for accurate biomarkers for early non-invasive colorectal cancer detection. We employed a genome-scale marker discovery method to…”
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