Search Results - "de Jesus, Hugo C. R."

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  1. 1

    Probing the acetylcholinesterase inhibitory activity of a novel Ru(II) polypyridyl complex and the supramolecular interaction by (STD)-NMR by Almeida, Marlon P., Kock, Flávio V.C., de Jesus, Hugo C.R., Carlos, Rose M., Venâncio, Tiago

    Published in Journal of inorganic biochemistry (01-11-2021)
    “…Currently, acetylcholinesterase (AChE) inhibitors are the only anti-Alzheimer drugs commercially available. Despite their wide use those drugs are all dose…”
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    Journal Article
  2. 2

    Enhancing protein fold determination by exploring the complementary information of chemical cross-linking and coevolutionary signals by dos Santos, Ricardo N, Ferrari, Allan J R, de Jesus, Hugo C R, Gozzo, Fábio C, Morcos, Faruck, Martínez, Leandro

    Published in Bioinformatics (01-07-2018)
    “…Abstract Motivation Elucidation of protein native states from amino acid sequences is a primary computational challenge. Modern computational and experimental…”
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  3. 3

    Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors by Silva, Taynara L., dos Santos, Deborah A., de Jesus, Hugo C.R., Brömme, Dieter, Fernandes, João B., Paixão, Marcio W., Corrêa, Arlene G., Vieira, Paulo C.

    Published in Bioorganic & medicinal chemistry (01-08-2020)
    “…[Display omitted] Cathepsin K (CatK) is a cysteine protease known for its potent collagenolytic activity, being recognized as an important target to the…”
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  4. 4

    New Synthetic Quinolines as Cathepsin K Inhibitors by Silva, Taynara, Bartolomeu, Aloisio, de Jesus, Hugo, de Oliveira, Kleber, Fernandes, João, Brömme, Dieter, Vieira, Paulo

    Published in Journal of the Brazilian Chemical Society (01-08-2020)
    “…Cathepsin K is a papain-like cysteine protease and is responsible for collagen degradation in bone tissue and thus represents an important target for the…”
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  5. 5

    Multiple Monohydroxylation Products from rac-Camphor by Marine Fungus Botryosphaeria sp. Isolated from Marine Alga Bostrychia radicans by de Jesus, Hugo, Jeller, Alex, Debonsi, Hosana, Alves, Péricles, Porto, André

    Published in Journal of the Brazilian Chemical Society (01-03-2017)
    “…This manuscript describes the biooxidation of rac-camphor using whole cells of marine-derived fungus Botryosphaeria sp. CBMAI 1197. The main biotransformation…”
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  6. 6

    Chemical constituents and larvicidal activity of Hymenaea courbaril fruit peel by Aguiar, José Cláudio D, Santiago, Gilvandete M P, Lavor, Patrícia L, Veras, Helenicy N H, Ferreira, Yana S, Lima, Michele A A, Arriaga, Angela M C, Lemos, Telma L G, Lima, Jefferson Q, de Jesus, Hugo C R, Alves, Péricles B, Braz-Filho, Raimundo

    Published in Natural product communications (01-12-2010)
    “…The chemical compositions of the essential oils from the peel of ripe and unripe fruits of Hymenaea courbaril L., obtained by hydrodistillation, were analyzed…”
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  7. 7

    Essential oil composition and variability in Hyptis fruticosa by Franco, Clóvis R. P., Alves, Péricles B., Andrade, Daniela M., Jesus, Hugo C. R. de, Silva, Eduardo J. S., Santos, Esdras A. B., Antoniolli, Ângelo R., Quintans-Júnior, Lucindo J.

    Published in Revista brasileira de farmacognosia (01-02-2011)
    “…The composition of six samples of essential oil (EO) extracted from leaves, flowers and seeds of several plants of Hyptis fruticosa Salzm. ex Benth.,…”
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