Search Results - "de Herreros, Antonio García"

Bioactivity descriptors for uncharacterized chemical compounds by Bertoni, Martino, Duran-Frigola, Miquel, Badia-i-Mompel, Pau, Pauls, Eduardo, Orozco-Ruiz, Modesto, Guitart-Pla, Oriol, Alcalde, Víctor, Diaz, Víctor M., Berenguer-Llergo, Antoni, Brun-Heath, Isabelle, Villegas, Núria, de Herreros, Antonio García, Aloy, Patrick

“…Chemical descriptors encode the physicochemical and structural properties of small molecules, and they are at the core of chemoinformatics. The broad release…”
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Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor by Herranz, Nicolás, Pasini, Diego, Díaz, Víctor M, Francí, Clara, Gutierrez, Arantxa, Dave, Natàlia, Escrivà, Maria, Hernandez-Muñoz, Inma, Di Croce, Luciano, Helin, Kristian, García de Herreros, Antonio, Peiró, Sandra

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LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival by Torres, Sofía, Garcia-Palmero, Irene, Herrera, Mercedes, Bartolomé, Rubén A, Peña, Cristina, Fernandez-Aceñero, M Jesús, Padilla, Guillermo, Peláez-García, Alberto, Lopez-Lucendo, María, Rodriguez-Merlo, Rufo, García de Herreros, Antonio, Bonilla, Félix, Casal, J Ignacio

“…Cancer-associated fibroblasts (CAF) are major mediators in tumor microenvironment. We investigated the changes in protein expression in colon cancer-associated…”
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A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition by Beltran, Manuel, Puig, Isabel, Peña, Cristina, García, José Miguel, Alvarez, Ana Belén, Peña, Raúl, Bonilla, Félix, de Herreros, Antonio García

“…Expression of Snail1 in epithelial cells triggers an epithelial-mesenchymal transition (EMT). Here, we demonstrate that the synthesis of Zeb2, a…”
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Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis by Alba-Castellón, Lorena, Olivera-Salguero, Rubén, Mestre-Farrera, Aida, Peña, Raúl, Herrera, Mercedes, Bonilla, Félix, Casal, J Ignacio, Baulida, Josep, Peña, Cristina, García de Herreros, Antonio

“…Snail1 transcriptional factor is essential for triggering epithelial-to-mesenchymal transition (EMT) and inducing tumor cell invasion. We report here an…”
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Cancer‐associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients by Herrera, Mercedes, Herrera, Alberto, Domínguez, Gemma, Silva, Javier, García, Vanesa, García, José M., Gómez, Irene, Soldevilla, Beatriz, Muñoz, Concepción, Provencio, Mariano, Campos‐Martin, Yolanda, García de Herreros, Antonio, Casal, Ignacio, Bonilla, Félix, Peña, Cristina

“…Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the…”
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Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature by HERRERA, Mercedes, ISLAM, Abul B. M. M. K, BONILLA, Félix, PENA, Cristina, HERRERA, Alberto, MARTIN, Paloma, GARCIA, Vanesa, SILVA, Javier, GARCIA, Jose M, SALAS, Clara, CASAL, Ignacio, GARCIA DE HERREROS, Antonio

“…Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment,…”
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PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation by Rodríguez, María Isabel, Peralta-Leal, Andreína, O'Valle, Francisco, Rodriguez-Vargas, José Manuel, Gonzalez-Flores, Ariannys, Majuelos-Melguizo, Jara, López, Laura, Serrano, Santiago, de Herreros, Antonio García, Rodríguez-Manzaneque, Juan Carlos, Fernández, Rubén, Del Moral, Raimundo G, de Almodóvar, José Mariano, Oliver, F Javier

“…PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however,…”
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Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains by Pascual-Reguant, Laura, Blanco, Enrique, Galan, Silvia, Le Dily, François, Cuartero, Yasmina, Serra-Bardenys, Gemma, Di Carlo, Valerio, Iturbide, Ane, Cebrià-Costa, Joan Pau, Nonell, Lara, de Herreros, Antonio García, Di Croce, Luciano, Marti-Renom, Marc A., Peiró, Sandra

“…Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic regions…”
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Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis by Escrivà, Maria, Peiró, Sandra, Herranz, Nicolás, Villagrasa, Patricia, Dave, Natàlia, Montserrat-Sentís, Bàrbara, Murray, Stephen A., Francí, Clara, Gridley, Thomas, Virtanen, Ismo, García de Herreros, Antonio

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Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition by Millanes-Romero, Alba, Herranz, Nicolás, Perrera, Valentina, Iturbide, Ane, Loubat-Casanovas, Jordina, Gil, Jesús, Jenuwein, Thomas, García de Herreros, Antonio, Peiró, Sandra

“…Although heterochromatin is enriched with repressive traits, it is also actively transcribed, giving rise to large amounts of noncoding RNAs. Although these…”
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Intracellular Signals Activated by Canonical Wnt Ligands Independent of GSK3 Inhibition and β-Catenin Stabilization by García de Herreros, Antonio, Duñach, Mireia

“…In contrast to non-canonical ligands, canonical Wnts promote the stabilization of β-catenin, which is a prerequisite for formation of the TCF4/β-catenin…”
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LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation by Iturbide, Ane, Pascual-Reguant, Laura, Fargas, Laura, Cebrià, Joan Pau, Alsina, Berta, García de Herreros, Antonio, Peiró, Sandra

“…Protein function is often regulated and controlled by posttranslational modifications, such as oxidation. Although oxidation has been mainly considered to be…”
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Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer by CANADAS, Israel, ROJO, Federico, MOJAL, Sergi, DE HERREROS, Antonio García, ROVIRA, Ana, ALBANELL, Joan, ARRIOLA, Edurne, TAUS, Alvaro, ARPI, Oriol, ARUMI-URIA, Montserrat, PIJUAN, Lara, MENENDEZ, Silvia, ZAZO, Sandra, DOMINE, Manuel, SALIDO, Marta

“…Met receptor phosphorylation is associated with poor prognosis in human small cell lung cancer (SCLC). The aim of our work was to investigate the effects of…”
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Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma by Sampson, Valerie B, David, Justin M, Puig, Isabel, Patil, Pratima U, de Herreros, Antonio García, Thomas, George V, Rajasekaran, Ayyappan K

“…The Wilms' tumor transcription factor (WT1) was originally classified as a tumor suppressor, but it is now known to also be associated with cancer progression…”
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Epithelial to mesenchymal transition in early stage endometrioid endometrial carcinoma by Montserrat, Nuria, PhD, Mozos, Ana, MD, Llobet, David, PhD, Dolcet, Xavier, PhD, Pons, Cristina, PhD, de Herreros, Antonio García, PhD, Matias-Guiu, Xavier, MD, Prat, Jaime, MD, PhD, FRCPath

“…Summary Epithelial to mesenchymal transition is thought to be implicated in tumor invasion and metastasis. To investigate its role in myometrial invasion,…”
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E-cadherin controls β-catenin and NF-κB transcriptional activity in mesenchymal gene expression by Solanas, Guiomar, Porta-de-la-Riva, Montserrat, Agustí, Cristina, Casagolda, David, Sánchez-Aguilera, Francisco, Larriba, María Jesús, Pons, Ferran, Peiró, Sandra, Escrivà, Maria, Muñoz, Alberto, Duñach, Mireia, de Herreros, Antonio García, Baulida, Josep

“…E-cadherin and its transcriptional repressor Snail1 (Snai1) are two factors that control epithelial phenotype. Expression of Snail1 promotes the conversion of…”
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E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations by Peña, Cristina, García, José Miguel, Silva, Javier, García, Vanesa, Rodríguez, Rufo, Alonso, Isabel, Millán, Isabel, Salas, Clara, de Herreros, Antonio García, Muñoz, Alberto, Bonilla, Félix

“…E-cadherin (CDH1) gene expression is strictly regulated. The transcriptional factors SNAIL and ZEB1 are involved in its repression, whereas activation of…”
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RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells by Ordóñez-Morán, Paloma, Larriba, María Jesús, Pálmer, Héctor G, Valero, Ruth A, Barbáchano, Antonio, Duñach, Mireia, de Herreros, Antonio García, Villalobos, Carlos, Berciano, María Teresa, Lafarga, Miguel, Muñoz, Alberto

“…The active vitamin D metabolite 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) inhibits proliferation and promotes differentiation of colon cancer cells through the…”
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Specific Phosphorylation of p120-Catenin Regulatory Domain Differently Modulates Its Binding to RhoA by Castaño, Julio, Solanas, Guiomar, Casagolda, David, Raurell, Imma, Villagrasa, Patricia, Bustelo, Xosé R., García de Herreros, Antonio, Duñach, Mireia

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