Search Results - "de Haas, Ria"

Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment by Frambach, Sanne J C M, de Haas, Ria, Smeitink, Jan A M, Rongen, Gerard A, Russel, Frans G M, Schirris, Tom J J

“…Atherosclerosis is a leading cause of cardiovascular disease worldwide, and hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on…”
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Wireless implantable micro-stimulation device for high frequency bilateral deep brain stimulation in freely moving mice by de Haas, Ria, Struikmans, Rolf, van der Plasse, Geoffrey, van Kerkhof, Linda, Brakkee, Jan H., Kas, Martien J.H., Westenberg, Herman G.M.

“…► This paper describes a new light-weight wireless implantable micro stimulator device for mice. ► The device delivers biphasic pulse patterns to two…”
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Identifying predictors of activity based anorexia susceptibility in diverse genetic rodent populations by Pjetri, Eneda, de Haas, Ria, de Jong, Simone, Gelegen, Cigdem, Oppelaar, Hugo, Verhagen, Linda A W, Eijkemans, Marinus J C, Adan, Roger A, Olivier, Berend, Kas, Martien J

“…Animal studies are very useful in detection of early disease indicators and in unravelling the pathophysiological processes underlying core psychiatric…”
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NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2 by Adjobo-Hermans, Merel J.W., de Haas, Ria, Willems, Peter H.G.M., Wojtala, Aleksandra, van Emst-de Vries, Sjenet E., Wagenaars, Jori A., van den Brand, Mariel, Rodenburg, Richard J., Smeitink, Jan A.M., Nijtmans, Leo G., Sazanov, Leonid A., Wieckowski, Mariusz R., Koopman, Werner J.H.

“…Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a…”
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Gait analysis in a mouse model resembling Leigh disease by de Haas, Ria, Russel, Frans G., Smeitink, Jan A.

“…[Display omitted] •Demonstrates the automated CatWalk gait analysis in a mouse model of Leigh disease.•CatWalk system sensitively assessed gait abnormalities…”
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Restoring cellular NAD(P)H levels by PPARα and LXRα stimulation to improve mitochondrial complex I deficiency by Frambach, Sanne J.C.M., de Haas, Ria, Smeitink, Jan A.M., Russel, Frans G.M., Schirris, Tom J.J.

“…Mitochondrial complex I (CI), the first multiprotein enzyme complex of the oxidative phosphorylation system, plays a crucial role in cellular energy…”
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Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice by Frambach, Sanne J.C.M., van de Wal, Melissa A.E., van den Broek, Petra H.H., Smeitink, Jan A.M., Russel, Frans G.M., de Haas, Ria, Schirris, Tom J.J.

“…Mitochondrial complex I (CI), the first multiprotein enzyme complex of the OXPHOS system, executes a major role in cellular ATP generation. Consequently,…”
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Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease by de Haas, Ria, Das, Devashish, Garanto, Alejandro, Renkema, Herma G., Greupink, Rick, van den Broek, Petra, Pertijs, Jeanne, Collin, Rob W. J., Willems, Peter, Beyrath, Julien, Heerschap, Arend, Russel, Frans G., Smeitink, Jan A.

“…Leigh Disease is a progressive neurometabolic disorder for which a clinical effective treatment is currently still lacking. Here, we report on the therapeutic…”
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To be or not to be pink(1): contradictory findings in an animal model for Parkinson’s disease by de Haas, Ria, Heltzel, Lisa C M W, Tax, Denise, van den Broek, Petra, Steenbreker, Hilbert, Verheij, Michel M M, Russel, Frans G M, Orr, Adam L, Nakamura, Ken, Smeitink, Jan A M

“…Abstract The PTEN-induced putative kinase 1 knockout rat (Pink1−/−) is marketed as an established model for Parkinson’s disease, characterized by development…”
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Behavioral pattern analysis and dopamine release in quinpirole-induced repetitive behavior in rats by de Haas, Ria, Nijdam, Annelies, Westra, Tjalke A, Kas, Martien JH, Westenberg, Herman GM

“…Obsessive–compulsive disorder (OCD) is a chronic and disabling psychiatric disease with a lifetime prevalence of 2–3%. People with OCD suffer from intrusive,…”
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Marked inbred mouse strain difference in the expression of quinpirole induced compulsive like behavior based on behavioral pattern analysis by de Haas, Ria, Seddik, Amir, Oppelaar, Hugo, Westenberg, Herman G.M, Kas, Martien J.H

“…Abstract Obsessive–compulsive disorder (OCD) is a chronic and complex psychiatric disorder with a lifetime prevalence of 2–3%. Recent work has shown that OCD…”
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Differential activation of alveolar and peritoneal macrophages from BCG-vaccinated guinea pigs by Cho, Hyosun, de Haas, Ria, Jeevan, Amminikutty, McMurray, David N

“…Summary We compared the effect of BCG vaccination on the mRNA expression of two prototypic cytokines, IL-12 (Type 1) and IL-10 (Type 2), in guinea pig resident…”
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