Search Results - "de Grandis, Rone Aparecido"
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1
Characterization and quantification of the compounds of the ethanolic extract from Caesalpinia ferrea stem bark and evaluation of their mutagenic activity
Published in Molecules (Basel, Switzerland) (08-10-2014)“…Caesalpinia ferrea Martius has traditionally been used in Brazil for many medicinal purposes, such as the treatment of bronchitis, diabetes and wounds. Despite…”
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2
In Vitro Evaluation of Acellular Collagen Matrices Derived from Porcine Pericardium: Influence of the Sterilization Method on Its Biological Properties
Published in Materials (21-10-2021)“…The aim of this study were characterize acellular collagen matrices derived from porcine pericardium (PP) and to evaluate their properties after sterilization…”
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3
Bothrops moojeni L-amino acid oxidase induces apoptosis and epigenetic modulation on Bcr-Abl + cells
Published in The journal of venomous animals and toxins including tropical diseases (14-12-2020)“…Resistance to apoptosis in chronic myeloid leukemia (CML) is associated with constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. The deregulated…”
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4
Resveratrol-Loaded Attalea funifera Oil Organogel Nanoparticles: A Potential Nanocarrier against A375 Human Melanoma Cells
Published in International journal of molecular sciences (28-07-2023)“…This study aimed to evaluate seed oil with or without resveratrol entrapped in organogel nanoparticles in vitro against A375 human melanoma tumor cells…”
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5
Evaluation of cytoprotective effects of compounds isolated from Copaifera langsdorffii Desf. against induced cytotoxicity by exposure to methylmercury and lead
Published in Natural product research (01-09-2020)“…Copaifera langsdorffii L. is one of the most known medicinal species in Brazil. Its leaves are rich in phenolic compounds with potential biological activities…”
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6
Soybean β-Conglycinin and Cowpea β-Vignin Peptides Inhibit Breast and Prostate Cancer Cell Growth: An In Silico and In Vitro Approach
Published in Foods (01-11-2024)“…B-cell lymphoma 2 protein (Bcl-2) is an important regulator of cell apoptosis. Inhibitors that mirror the structural domain 3 (BH3) of Bcl-2 can activate…”
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7
Avaliação da Atividade Antibacteriana do Gengibre (Zingiber officinale Roscoe) e do Maracujá Amarelo (Passiflora edulis Sims)
Published in Revista de ciências farmacêuticas básica e aplicada (01-01-2015)“…Nas últimas décadas, inúmeros estudos têm sido realizados para conferir às plantas seu real valor na terapia. São muitos os fatores que vem colaborando com o…”
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8
Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells
Published in Food and chemical toxicology (01-02-2020)“…Abnormal epigenetic alterations are one of the keystones of cancer development. Epigenetic targeting drugs have become a promising and effective cancer therapy…”
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9
Novel Ru(II)-bipyridine/phenanthroline-lapachol complexes as potential anti-cancer agents
Published in Journal of inorganic biochemistry (01-12-2022)“…For the first time, we herein report on the syntheses of two new Ru(II)/bipyridine/phenanthroline complexes containing lapachol as ligand: complex (1), [Ru…”
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10
Hydroalcoholic Extract of Myrcia bella Loaded into a Microemulsion System: A Study of Antifungal and Mutagenic Potential
Published in Planta medica (01-04-2022)“…is a medicinal plant used for the treatment of diabetes, hemorrhages, and hypertension in Brazilian folk medicine. Considering that plant extracts are…”
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11
Resveratrol-Loaded IAttalea funifera/I Oil Organogel Nanoparticles: A Potential Nanocarrier against A375 Human Melanoma Cells
Published in International journal of molecular sciences (01-07-2023)“…This study aimed to evaluate Attalea funifera seed oil with or without resveratrol entrapped in organogel nanoparticles in vitro against A375 human melanoma…”
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12
Novel lawsone-containing ruthenium(II) complexes: Synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
Published in Bioorganic chemistry (01-04-2019)“…[Display omitted] •A series of novel ruthenium complexes containing lawsone were synthesized.•The complexes showed potent anticancer activity against several…”
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13
Cyto-genotoxic evaluation of novel anti-tubercular copper (II) complexes containing isoniazid-based ligands
Published in Regulatory toxicology and pharmacology (01-06-2020)“…Considering the promising previous results of Cu (II) complexes with isoniazid active ligand against Mycobacterium tuberculosis, the main causative agent of…”
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14
In vitro evaluation of the cyto-genotoxic potential of Ruthenium(II) SCAR complexes: a promising class of antituberculosis agents
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-03-2016)“…[Display omitted] •Complexes SCAR 5 and 4 are more cytotoxic while SCAR 6 exhibited selectivity action•SCAR 6 induces frameshift mutations in the Ames test…”
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15
Assessment of the antibacterial, cytotoxic and mutagenic potential of the phenolic-rich hydroalcoholic extract from Copaifera trapezifolia Hayne leaves
Published in Journal of medical microbiology (01-09-2016)“…Copaifera trapezifolia Hayne occurs in the Atlantic Rainforest, which is considered one of the most important and endangered tropical forests on the planet…”
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16
Mutagenicity and chemopreventive activities of Astronium species assessed by Ames test
Published in Regulatory toxicology and pharmacology (01-08-2015)“…•Astronium spp. has been investigated for medicinal activity.•None of the extracts showed mutagenic activity.•The protective effects were evaluated against…”
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17
Evaluation of cytoprotective effects of compounds isolated from Copaifera langsdorffii Desf. against induced cytotoxicity by exposure to methylmercury and lead
Published in Natural product research (09-01-2019)“…Copaifera langsdorffii L. is one of the most known medicinal species in Brazil. Its leaves are rich in phenolic compounds with potential biological activities…”
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Journal Article -
18
Avaliação da Atividade Antibacteriana do Gengibre (Zingiber officinale Roscoe) e do Maracujá Amarelo (Passiflora edulis Sims)
Published in Revista de ciências farmacêuticas básica e aplicada (01-09-2015)“…Nas últimas décadas, inúmeros estudos têm sido realizados para conferir às plantas seu real valor na terapia. São muitos os fatores que vem colaborando com o…”
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19
Mutagenicity and antimutagenicity of six Brazilian Byrsonima species assessed by the Ames test
Published in BMC complementary and alternative medicine (05-06-2014)“…In various regions of Brazil, several species of the genus Byrsonima (Malpighiaceae) are widely used to treat gastrointestinal complications. This genus has…”
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