Search Results - "de Gracia, Francisco Garcia"

Differences in the internalization of self-inactivating VSVG-pseudotyped murine leukemia virus-based vectors in human and murine cells by Acevedo, Mónica Loreto, García-de Gracia, Francisco, Miranda-Cárdenas, Camila, Soto-Rifo, Ricardo, Aguayo, Francisco, León, Oscar

“…•The steps of SIN-VSVG-MLV replication in various cell types was analyzed.•SIN-VSVG-MLV replication events occurred with the greatest efficiency in HeLa…”
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HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA by Ajamian, Lara, Abel, Karen, Rao, Shringar, Vyboh, Kishanda, García-de-Gracia, Francisco, Soto-Rifo, Ricardo, Kulozik, Andreas E, Gehring, Niels H, Mouland, Andrew J

“…Unspliced, genomic HIV-1 RNA (vRNA) is a component of several ribonucleoprotein complexes (RNP) during the viral replication cycle. In earlier work, we…”
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Epitranscriptomic regulation of HIV-1 full-length RNA packaging by Pereira-Montecinos, Camila, Toro-Ascuy, Daniela, Ananías-Sáez, Catarina, Gaete-Argel, Aracelly, Rojas-Fuentes, Cecilia, Riquelme-Barrios, Sebastián, Rojas-Araya, Bárbara, García-de-Gracia, Francisco, Aguilera-Cortés, Paulina, Chnaiderman, Jonás, Acevedo, Mónica L, Valiente-Echeverría, Fernando, Soto-Rifo, Ricardo

“…Abstract During retroviral replication, the full-length RNA serves both as mRNA and genomic RNA. However, the mechanisms by which the HIV-1 Gag protein selects…”
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A Rev-CBP80-eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA by Toro-Ascuy, Daniela, Rojas-Araya, Bárbara, García-de-Gracia, Francisco, Rojas-Fuentes, Cecilia, Pereira-Montecinos, Camila, Gaete-Argel, Aracelly, Valiente-Echeverría, Fernando, Ohlmann, Théophile, Soto-Rifo, Ricardo

“…Abstract Gag synthesis from the full-length unspliced mRNA is critical for the production of the viral progeny during human immunodeficiency virus type-1…”
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The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses by Bonaventure, Boris, Rebendenne, Antoine, Chaves Valadão, Ana Luiza, Arnaud‐Arnould, Mary, Gracias, Ségolène, Garcia de Gracia, Francisco, McKellar, Joe, Labaronne, Emmanuel, Tauziet, Marine, Vivet‐Boudou, Valérie, Bernard, Eric, Briant, Laurence, Gros, Nathalie, Djilli, Wassila, Courgnaud, Valérie, Parrinello, Hugues, Rialle, Stéphanie, Blaise, Mickaël, Lacroix, Laurent, Lavigne, Marc, Paillart, Jean‐Christophe, Ricci, Emiliano P, Schulz, Reiner, Jouvenet, Nolwenn, Moncorgé, Olivier, Goujon, Caroline

“…Genome‐wide screens are powerful approaches to unravel regulators of viral infections. Here, a CRISPR screen identifies the RNA helicase DDX42 as an intrinsic…”
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CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev by García-de-Gracia, Francisco, Gaete-Argel, Aracelly, Riquelme-Barrios, Sebastián, Pereira-Montecinos, Camila, Rojas-Araya, Bárbara, Aguilera, Paulina, Oyarzún-Arrau, Aarón, Rojas-Fuentes, Cecilia, Acevedo, Mónica L., Chnaiderman, Jonás, Valiente-Echeverría, Fernando, Toro-Ascuy, Daniela, Soto-Rifo, Ricardo

“…Translation initiation of the human immunodeficiency virus type-1 (HIV-1) full-length RNA has been shown to occur through cap-dependent and IRES-driven…”
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DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain by Fröhlich, Alvaro, Rojas-Araya, Bárbara, Pereira-Montecinos, Camila, Dellarossa, Alessandra, Toro-Ascuy, Daniela, Prades-Pérez, Yara, García-de-Gracia, Francisco, Garcés-Alday, Andrea, Rubilar, Paulina S., Valiente-Echeverría, Fernando, Ohlmann, Théophile, Soto-Rifo, Ricardo

“…DEAD-box RNA helicase DDX3 is a host factor essential for HIV-1 replication and thus, a potential target for novel therapies aimed to overcome viral…”
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Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs by Rebendenne, Antoine, Roy, Priyanka, Bonaventure, Boris, Chaves Valadão, Ana Luiza, Desmarets, Lowiese, Arnaud-Arnould, Mary, Rouillé, Yves, Tauziet, Marine, Giovannini, Donatella, Touhami, Jawida, Lee, Yenarae, DeWeirdt, Peter, Hegde, Mudra, Urbach, Serge, Koulali, Khadija El, de Gracia, Francisco Garcia, McKellar, Joe, Dubuisson, Jean, Wencker, Mélanie, Belouzard, Sandrine, Moncorgé, Olivier, Doench, John G., Goujon, Caroline

“…CRISPR knockout (KO) screens have identified host factors regulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we…”
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HIV-2 genomic RNA accumulates in stress granules in the absence of active translation by Soto-Rifo, Ricardo, Valiente-Echeverria, Fernando, Rubilar, Paulina S, Garcia-de-Gracia, Francisco, Ricci, Emiliano P, Limousin, Taran, Décimo, Didier, Mouland, Andrew J, Ohlmann, Théophile

“…During the post-transcriptional events of the HIV-2 replication cycle, the full-length unspliced genomic RNA (gRNA) is first used as an mRNA to synthesize Gag…”
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