Search Results - "de Goeij, Anton"
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Surviving in a Marine Desert: The Sponge Loop Retains Resources Within Coral Reefs
Published in Science (American Association for the Advancement of Science) (04-10-2013)“…Ever since Darwin's early descriptions of coral reefs, scientists have debated how one of the world's most productive and diverse ecosystems can thrive in the…”
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2
Student participation in governance of medical and veterinary education: experiences and perspectives of student representatives and program directors
Published in Advances in health sciences education : theory and practice (01-10-2019)“…Student participation in governance of education is of growing interest. However, it remains unclear what factors render this participation in institutional…”
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3
Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms
Published in PloS one (23-11-2009)“…Exposure to energy restriction during childhood and adolescence is associated with a lower risk of developing colorectal cancer (CRC). Epigenetic dysregulation…”
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4
Dietary heme iron and the risk of colorectal cancer with specific mutations in KRAS and APC
Published in Carcinogenesis (New York) (01-12-2013)“…Red meat intake has been linked to increased colorectal cancer (CRC) risk. Although the underlying mechanisms remain unclear, experimental studies suggest a…”
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5
Alcohol consumption, type of alcoholic beverage and risk of colorectal cancer at specific subsites
Published in International journal of cancer (15-11-2008)“…Within the Netherlands Cohort Study on diet and cancer, we investigated associations between total alcohol consumption, specific alcoholic beverage consumption…”
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Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer
Published in Carcinogenesis (New York) (01-09-2008)“…Intake of dietary factors that serve as methyl group donors may influence promoter hypermethylation in colorectal carcinogenesis. We investigated whether…”
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Genetic Variants of Methyl Metabolizing Enzymes and Epigenetic Regulators: Associations with Promoter CpG Island Hypermethylation in Colorectal Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-11-2009)“…Aberrant DNA methylation affects carcinogenesis of colorectal cancer. Folate metabolizing enzymes may influence the bioavailability of methyl groups, whereas…”
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Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP)
Published in PloS one (05-04-2011)“…We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). In the…”
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9
Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study
Published in International journal of epidemiology (01-10-2010)“…Background Energy restriction during childhood and adolescence is suggested to lower colorectal cancer (CRC) risk. We investigated this in the Netherlands…”
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10
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: The Netherlands cohort study on diet and cancer
Published in Cancer research (Chicago, Ill.) (15-06-2003)“…Sporadic colorectal cancer (CRC) is characterized by genetic and epigenetic changes such as regional DNA hypermethylation and global DNA hypomethylation…”
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K-ras mutations and RASSF1A promoter methylation in colorectal cancer
Published in Oncogene (23-05-2002)“…Human cancer is characterized by genetic and epigenetic alterations. In this study we provide evidence for the interruption of Ras signaling in sporadic…”
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Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer
Published in Cancer causes & control (01-01-2011)“…Dietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). Among 609 CRC cases and 1,663 subcohort members of the…”
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13
K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study
Published in Carcinogenesis (New York) (01-04-2003)“…Activation of K-ras oncogene has been implicated in colorectal carcinogenesis, being mutated in 30–60% of the adenocarcinomas. In this study, 737 incident…”
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Dietary fat and risk of colon and rectal cancer with aberrant MLH1 expression, APC or KRAS genes
Published in Cancer causes & control (01-10-2007)“…Objective To investigate baseline fat intake and the risk of colon and rectal tumors lacking MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) repair…”
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Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study
Published in BMC cancer (15-12-2005)“…The early to intermediate stages of the majority of colorectal tumours are thought to be driven by aberrations in the Wnt (APC, CTNNB1) and Ras (K-ras)…”
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16
Inhibiting MMP activity prevents the development of endometriosis in the chicken chorioallantoic membrane model
Published in Human reproduction (Oxford) (01-10-2004)“…BACKGROUND: Matrix metalloproteinases (MMPs) are essential for extracellular matrix remodelling and may contribute to the development of endometriosis…”
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17
Dietary folate and APC mutations in sporadic colorectal cancer
Published in The Journal of nutrition (01-12-2006)“…Folate deficiency has been associated with colorectal cancer risk and may be involved in colorectal carcinogenesis through increased chromosome instability,…”
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Cigarette Smoking and Colorectal Cancer: APC Mutations, hMLH1 Expression, and GSTM1 and GSTT1 Polymorphisms
Published in American journal of epidemiology (01-05-2005)“…The contribution of cigarette smoking to sporadic colorectal cancer may differ according to molecular aspects of the tumor or according to glutathione…”
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Academic and scientific education in medical curricula in the Netherlands: a programme director’s view
Published in Perspectives on medical education (01-09-2013)“…None…”
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Alcohol consumption, alcohol dehydrogenase 1C ( ADH1C ) genotype, and risk of colorectal cancer in the Netherlands Cohort Study on diet and cancer
Published in Alcohol (Fayetteville, N.Y.) (01-05-2011)“…Abstract Within the Netherlands Cohort Study (1986), we examined associations between alcohol consumption, the alcohol dehydrogenase 1C ( ADH1C ) genotype, and…”
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