Search Results - "de Freitas Paulo, Tércio"
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Further Insights into the Oxidative Pathway of Thiocarbonyl-Type Antitubercular Prodrugs: Ethionamide, Thioacetazone, and Isoxyl
Published in Chemical research in toxicology (16-08-2021)“…A chemical activation study of the thiocarbonyl-type antitubercular prodrugs, ethionamide (ETH), thioacetazone (TAZ), and isoxyl (ISO), was performed…”
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Anti-inflammatory withajardins from the leaves of Athenaea velutina
Published in Phytochemistry (Oxford) (01-11-2022)“…Withajardins, uncommon modified withanolide-type steroids, have been isolated exclusively from plants of the Solanaceae family so far. Two undescribed…”
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Thionicotinamide SAM on Gold: Adsorption Studies and Electroactivity
Published in Electroanalysis (New York, N.Y.) (01-05-2009)“…STM and impedance results of the self‐assembled monolayer (SAM) formed with thionicotinamide (TNA) on gold indicate the presence of defects that increase with…”
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A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity
Published in Journal of inorganic biochemistry (01-09-2020)“…Nitric oxide (NO) and nitroxyl (HNO) have gained broad attention due to their roles in several physiological and pathophysiological processes. Remarkably,…”
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Pentacyanoferrate(II) complex of pyridine-4- and pyrazine-2-hydroxamic acid as source of HNO: investigation of anti-tubercular and vasodilation activities
Published in Journal of biological inorganic chemistry (01-09-2020)“…A pharmacophore design approach, based on the coordination chemistry of an intimate molecular hybrid of active metabolites of pro-drugs, known to release…”
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