Search Results - "de Freitas Oliveira, Johny Wysllas"
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Application of Dithiocarbamates as Potential New Antitrypanosomatids-Drugs: Approach Chemistry, Functional and Biological
Published in Molecules (Basel, Switzerland) (01-08-2019)“…Dithiocarbamates represent a class of compounds that were evaluated in different biomedical applications because of their chemical versatility. For this…”
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Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs
Published in Molecules (Basel, Switzerland) (03-06-2020)“…Neglected tropical diseases such as Chagas disease and leishmaniasis affect millions of people around the world. Both diseases affect various parts of the…”
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VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases
Published in Vaccines (Basel) (05-03-2021)“…Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping…”
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Silver Nanoparticles Containing Fucoidan Synthesized by Green Method Have Anti-Trypanosoma cruzi Activity
Published in Nanomaterials (Basel, Switzerland) (15-06-2022)“…The brown seaweed Spatoglossum schröederi synthesizes three bioactive fucoidans, the most abundant of which is fucan A. This fucoidan was extracted and its…”
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Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity
Published in Pharmaceutics (24-11-2020)“…IVS320 (3a,10b-dihydro-1 -cyclopenta[ ]naphtho[2,3- ]furan-5,10-dione) is a naphthoquinone that has low solubility in aqueous medium, a physical behavior that…”
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Antimicrobial Activity of Chitosan Oligosaccharides with Special Attention to Antiparasitic Potential
Published in Marine drugs (12-02-2021)“…The global rise of infectious disease outbreaks and the progression of microbial resistance reinforce the importance of researching new biomolecules. Obtained…”
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Tephrosia toxicaria (Sw.) Pers. extracts: Screening by examining aedicidal action under laboratory and field conditions along with its antioxidant, antileishmanial, and antimicrobial activities
Published in PloS one (01-01-2023)“…An increase in the incidence of arboviral, microbial and parasitic infections, and to disorders related to oxidative stress has encouraged the development of…”
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Insights of antiparasitic activity of sodium diethyldithiocarbamate against different strains of Trypanosoma cruzi
Published in Scientific reports (27-05-2021)“…Chagas disease is caused by Trypanosoma cruzi and affects thousands of people. Drugs currently used in therapy are toxic and have therapeutic limitations. In…”
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Quantum Biochemistry Screening and In Vitro Evaluation of Leishmania Metalloproteinase Inhibitors
Published in International journal of molecular sciences (01-08-2022)“…Leishmanolysin, also known as major promastigote protease (PSP) or gp63, is the most abundant surface glycoprotein of Leishmania spp., and has been extensively…”
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In Vitro Validation of Antiparasitic Activity of PLA-Nanoparticles of Sodium Diethyldithiocarbamate against Trypanosoma cruzi
Published in Pharmaceutics (24-02-2022)“…is a protozoan parasite responsible for Chagas disease, which affects millions around the world and is not treatable in its chronic stage. Sodium…”
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Tephrosia toxicaria
Published in PloS one (11-01-2023)“…An increase in the incidence of arboviral, microbial and parasitic infections, and to disorders related to oxidative stress has encouraged the development of…”
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pH-responsive phthalate cashew gum nanoparticles for improving drugs delivery and anti-Trypanosoma cruzi efficacy
Published in International journal of biological macromolecules (01-03-2023)“…Nanotechnology is a crucial technology in recent years has resulted in new and creative applications of nanomedicine. Polymeric nanoparticles have increasing…”
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13
Pontent bioative and broad-spectrum analogs of the scorpion peptide stigmurin
Published in Toxicon (Oxford) (05-10-2019)Get full text
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Antiparasitic, antiproliferative and toxicity activities of two analogs peptides from Stigmurin of the scorpion Tityus stigmurus
Published in Toxicon (Oxford) (05-10-2019)Get full text
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The evaluation of in vitro antichagasic and anti-SARS-CoV-2 potential of inclusion complexes of β- and methyl-β-cyclodextrin with naphthoquinone
Published in Journal of drug delivery science and technology (01-03-2023)“…The compound 3a,10b-dihydro-1H-cyclopenta[b]naphtho[2,3-d]furan-5,10-dione (IVS320) is a naphthoquinone with antifungal and antichagasic potential, which…”
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Tephrosia toxicaria (Sw.) Pers. extracts: Screening by examining aedicidal action under laboratory and field conditions along with its antioxidant, antileishmanial, and antimicrobial activities
Published in PloS one (01-01-2023)“…An increase in the incidence of arboviral, microbial and parasitic infections, and to disorders related to oxidative stress has encouraged the development of…”
Get full text
Journal Article