Search Results - "de Freitas, Luiz A R"
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An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection
Published in PLoS neglected tropical diseases (01-06-2024)“…The spleen plays a pivotal role in the pathogenesis of visceral leishmaniasis. In severe forms of the disease, the spleen undergoes changes that can compromise…”
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Assessment of histological liver alterations in dogs naturally infected with Leishmania infantum
Published in Parasites & vectors (16-10-2019)“…The liver plays a central role in the development of canine visceral leishmaniasis. Studies of natural infection in animals and humans indicate a direct…”
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3
Extracellular vesicles from Leishmania-infected macrophages confer an anti-infection cytokine-production profile to naïve macrophages
Published in PLoS neglected tropical diseases (01-09-2014)“…Extracellular vesicles (EVs) are structures with phospholipid bilayer membranes and 100-1000 nm diameters. These vesicles are released from cells upon…”
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4
Severe clinical presentation of visceral leishmaniasis in naturally infected dogs with disruption of the splenic white pulp
Published in PloS one (03-02-2014)“…In this work, we investigated the association between the disruption of splenic lymphoid tissue and the severity of visceral leishmaniasis in dogs. Clinical…”
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5
Immune and inflammatory responses to Leishmania amazonensis isolated from different clinical forms of human leishmaniasis in CBA mice
Published in Memórias do Instituto Oswaldo Cruz (01-02-2011)“…Leishmania amazonensis causes different diseases depending on the host and parasitic virulence factors. In this study, CBA mice were infected with L…”
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6
Computational pathology, new horizons and challenges for anatomical pathology
Published in Surgical and experimental pathology (20-06-2022)“…Abstract The emergence of digital pathology environments and the application of computer vision to the analysis of histological sections has given rise to a…”
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Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America
Published in JGH open (01-12-2022)“…Background and Aim Obliterative portal venopathy (OPV) is one of the causes of non‐cirrhotic portal hypertension. However, many aspects of OPV remain unclear,…”
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Anti‐Golgi complex antibodies during pegylated‐interferon therapy for hepatitis C
Published in Liver international (01-11-2006)“…: Background/Aim: Pegylated interferon (Peg‐IFN) plus ribavirin is the standard therapy for hepatitis C. Peg‐IFN has several antiviral mechanisms, but its role…”
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9
Disorganization of spleen compartments and dermatitis in canine visceral leishmaniasis
Published in Surgical and experimental pathology (30-05-2019)“…Abstract Canine visceral leishmaniasis is associated with splenic changes that may interfere with the surveillance of blood borne antigens. Dogs with terminal…”
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10
A case of conventional treatment failure in visceral leishmaniasis: leukocyte distribution and cytokine expression in splenic compartments
Published in BMC infectious diseases (09-09-2014)“…In this paper we study the distribution of leukocyte populations and of cytokine-producing cells in the spleen of a patient with visceral leishmaniasis…”
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11
1,8-Cineole protects against liver failure in an in-vivo murine model of endotoxemic shock
Published in Journal of pharmacy and pharmacology (01-04-2001)“…The effects of 1,8‐cineole on d‐galactosamine/lipopolysaccharide (GalN/LPS)‐induced shock model of liver injury was investigated in mice. The co‐administration…”
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12
Heat therapy for cutaneous leishmaniasis elicits a systemic cytokine response similar to that of antimonial (Glucantime) therapy
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-07-2006)“…Controlled heat delivered as radio waves has been used successfully in the treatment of cutaneous leishmaniasis (CL). Here we investigated whether local heat…”
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13
Concomitant early mucosal and cutaneous leishmaniasis in Brazil
Published in The American journal of tropical medicine and hygiene (01-08-2006)“…Mucosal leishmaniasis (ML) is often clinically silent until reaching a highly advanced state. In this prospective study, 6 of 220 patients with early cutaneous…”
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14
MAP Kinase Pathways: Molecular Roads to Primary Acral Lentiginous Melanoma
Published in The American journal of dermatopathology (01-12-2015)“…The etiology and pathogenesis of lentiginous acral melanomas are poorly understood. Recent studies have postulated that DNA repair mechanisms and cell growth…”
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15
Nonalcoholic steatohepatitis in morbid obese patients: coffee consumption vs. disease severity
Published in Annals of hepatology (01-05-2016)“…AbstractIntroduction. Obesity correlates with nonalcoholic fatty liver disease (NAFLD) and occurs in 90 to 100% of severely obese individuals (body mass index…”
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16
Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
Published in Annals of hepatology (01-01-2011)“…The main objective of this study was to describe the profile of patients who were benefitted in a collective effort to perform liver biopsies in Bahia, Brazil…”
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Clinical and histopathological features of NASH in workers exposed to chemicals with or without associated metabolic conditions
Published in Liver international (01-04-2004)“…Background/Aims: Non‐alcoholic steatohepatitis (NASH) has been associated with exposure to chemicals among workers from an industrial complex in Brazil. We…”
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Non-alcoholic fatty liver disease and insulin resistance: importance of risk factors and histological spectrum
Published in European journal of gastroenterology & hepatology (01-08-2005)“…BACKGROUNDNon-alcoholic fatty liver disease (NAFLD) has been associated with several metabolic conditions (MC) and secondary causes, but the relationship…”
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19
Association between skin parasitism and a granulomatous inflammatory pattern in canine visceral leishmaniosis
Published in Parasitology research (1987) (01-01-2004)“…In this work we examined 76 stray dogs from an area of endemic visceral leishmaniosis, in order to determine whether the presence of skin inflammation or a…”
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Clinical, histologic and serologic evaluation of patients with acute non-A-E hepatitis in north-eastern Brazil: is it an infectious disease?
Published in International journal of infectious diseases (01-09-2003)“…Non-A-E hepatitis and acute cryptogenic hepatitis are the names given to the disease of patients with clinical hepatitis, but in whom serologic evidence of A-E…”
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