Search Results - "de Farias, Sávio Torres"
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RNP-world: The ultimate essence of life is a ribonucleoprotein process
Published in Genetics and molecular biology (01-01-2022)“…The fundamental essence of life is based on process of interaction between nucleic acids and proteins. In a prebiotic world, amino acids, peptides, ions, and…”
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The Ancient History of Peptidyl Transferase Center Formation as Told by Conservation and Information Analyses
Published in Life (Basel, Switzerland) (05-08-2020)“…The peptidyl transferase center (PTC) is the catalytic center of the ribosome and forms part of the 23S ribosomal RNA. The PTC has been recognized as the…”
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3
Major evolutionary transitions before cells: A journey from molecules to organisms
Published in Progress in biophysics and molecular biology (01-09-2024)“…Basing on logical assumptions and necessary steps of complexification along biological evolution, we propose here an evolutionary path from molecules to cells…”
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Structural Computational Analysis of the Natural History of Class I aminoacyl-tRNA Synthetases Suggests their Role in Establishing the Genetic Code
Published in Journal of molecular evolution (01-12-2021)“…The evolutionary history of Class I aminoacyl-tRNA synthetases (aaRS) through the reconstruction of ancestral sequences is presented. From structural molecular…”
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Viruses as a survival strategy in the armory of life
Published in History and philosophy of the life sciences (01-12-2019)“…Viruses have generally been thought of as infectious agents. New data on mimivirus, however, suggests a reinterpretation of this thought. Earth's biosphere…”
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The Theory of Chemical Symbiosis: A Margulian View for the Emergence of Biological Systems (Origin of Life)
Published in Acta biotheoretica (01-03-2021)“…The theory of chemical symbiosis (TCS) suggests that biological systems started with the collaboration of two polymeric molecules existing in early Earth:…”
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Natural History of DNA-Dependent DNA Polymerases: Multiple Pathways to the Origins of DNA
Published in Viruses (01-03-2023)“…One of the major evolutionary transitions that led to DNA replacing RNA as the primary informational molecule in biological systems is still the subject of an…”
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Performance of intron 7 of the β -fibrinogen gene for phylogenetic analysis: An example using gladiator frogs, Boana Gray, 1825 (Anura, Hylidae, Cophomantinae)
Published in ZooKeys (22-02-2023)“…, the third largest genus of Hylinae, has cryptic morphological species. The potential applicability of is explored to propose a robust phylogeny of . The…”
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Prediction of MicroRNAs in the Epstein–Barr Virus Reveals Potential Targets for the Viral Self-Regulation
Published in Indian journal of microbiology (01-03-2019)“…Studies involving miRNAs have opened discussions about their broad participation in viral infections. Regarding the Human gammaherpesvirus 4 or Epstein–Barr…”
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Origin of life: Drawing the big picture
Published in Progress in biophysics and molecular biology (01-07-2023)“…Trying to provide a broad overview about the origin of life in Earth, the most significant transitions of life before cells are listed and discussed. The…”
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Life and living beings under the perspective of organic macrocodes
Published in BioSystems (01-08-2021)“…A powerful and concise concept of life is crucial for studies aiming to understand the characteristics that emerged from an inorganic world. Among biologists,…”
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Entering the labyrinth: A hypothesis about the emergence of metabolism from protobiotic routes
Published in BioSystems (01-10-2022)“…The occurrence of organized chemical transformations defined as metabolism is one of the most important characteristics of life. Surprisingly though, there is…”
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Oyster (Crassostrea gasar) gastrointestinal tract microbiota and immunological responses after antibiotic administration
Published in Latin american journal of aquatic research (01-03-2019)“…Microbiota, the microorganisms that colonize living organisms. Oysters rely exclusively on an innate immune system. This study characterized the cultivable…”
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Transfer RNA: The molecular demiurge in the origin of biological systems
Published in Progress in biophysics and molecular biology (01-07-2020)“…Herein, we review recent works on the role that the tRNA molecule played in the early origins of biological systems. tRNAs gave origin to the first genes…”
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Is it possible that cells have had more than one origin?
Published in BioSystems (01-04-2021)“…Cells occupy a prominent place in the history of life in Earth. The central role of cellular organization can be understood by the fact that “cellular life” is…”
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Structural analyzes suggest that MiSSP13 and MiSSP16.5 may act as proteases inhibitors during ectomycorrhiza establishment in Laccaria bicolor
Published in BioSystems (01-04-2024)“…•The signaling process during mycorrhiza establishment involves intense molecular communication between symbionts. It has been suggested that a group of…”
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Suggested phylogeny of tRNAs based on the construction of ancestral sequences
Published in Journal of theoretical biology (21-10-2013)“…The origin and evolution of life on the planet is one of the most intriguing challenges in life sciences and, for some researchers, it is centered in the…”
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A neutral evolution test derived from a theoretical amino acid substitution model
Published in Journal of theoretical biology (21-04-2019)“…•A mathematical model that explicitly considers nucleotides, codons, amino acids, and the degeneracy of the standard genetic code is elaborated.•The model is…”
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Prebiotic chemical refugia: multifaceted scenario for the formation of biomolecules in primitive Earth
Published in Theory in biosciences = Theorie in den Biowissenschaften (01-11-2022)“…The origin of life was a cosmic event happened on primitive Earth. A critical problem to better understand the origins of life in Earth is the search for…”
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Peptidyl Transferase Center and the Emergence of the Translation System
Published in Life (Basel, Switzerland) (25-04-2017)“…In this work, the three-dimensional (3D) structure of the ancestral Peptidyl Transferase Center (PTC) built by concatamers of ancestral sequences of tRNAs was…”
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