Search Results - "de Farias, Carine Coneglian"
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Clozapine and olanzapine are better antioxidants than haloperidol, quetiapine, risperidone and ziprasidone in in vitro models
Published in Biomedicine & pharmacotherapy (01-07-2016)“…Abstract Although the etiopathogenic mechanisms of schizophrenia (SCZ) are unknown, evidences suggest that excessive free radical production or oxidative…”
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Comparison of the antioxidant potential of antiparkinsonian drugs in different in vitro models
Published in Brazilian Journal of Pharmaceutical Sciences (01-12-2014)“…Parkinson's disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta. Furthermore, oxidative…”
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Highly specific changes in antioxidant levels and lipid peroxidation in Parkinson’s disease and its progression: Disease and staging biomarkers and new drug targets
Published in Neuroscience letters (23-03-2016)“…•Plasma MDA may serve as a highly sensitive and specific disease biomarker of PD.•Plasma LOOH and SOD expression may serve as staging biomarkers of PD.•New…”
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Association of -94 ATTG insertion/deletion NFkB1 and c.126G>A NFkBIA genetic polymorphisms with oxidative and nitrosative stress biomarkers in Brazilian subjects with Parkinson’s Disease
Published in Neuroscience letters (01-01-2021)“…•Oxidative/nitrosative stress is influenced by NFκB1 and NFκBIA polymorphisms.•NFκB1 and NFκBIA polymorphisms are not directly associated with PD.•Plasma LOOH…”
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Lowered paraoxonase 1 (PON1) activity is associated with increased cytokine levels in drug naïve first episode psychosis
Published in Schizophrenia research (01-08-2015)“…Abstract Background Activated immune-inflammatory pathways play an important role in the pathophysiology of schizophrenia. Paraoxonase 1 (PON1) activity is…”
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Indices of insulin resistance and glucotoxicity are not associated with bipolar disorder or major depressive disorder, but are differently associated with inflammatory, oxidative and nitrosative biomarkers
Published in Journal of affective disorders (01-11-2017)“…Insulin resistance (IR) is a key factor in diabetes mellitus, metabolic syndrome (MetS) and obesity and may occur in mood disorders and tobacco use disorder…”
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Parkinson's Disease is Accompanied by Intertwined Alterations in Iron Metabolism and Activated Immune-inflammatory and Oxidative Stress Pathways
Published in CNS & neurological disorders drug targets (01-01-2017)“…Parkinson's disease (PD) is a neurodegenerative disorder characterized by a complex interplay between peripheral and central inflammatory and oxidative stress…”
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