Search Results - "de Faria, Fernanda Costas C"
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Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors
Published in PloS one (14-10-2022)“…Mutation in the CTNNB1 gene, leading to a deregulation of the WTN/β-catenin pathway, is a common feature of desmoid tumors (DTs). Many β-catenin inhibitors…”
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2
Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches
Published in Human cell : official journal of Human Cell Research Society (01-05-2023)“…Sarcomas are rare malignancies, the number of reports is limited, and this rarity makes further research difficult even though liposarcoma is one of major…”
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NFκB pathway and microRNA-9 and -21 are involved in sensitivity to the pterocarpanquinone LQB-118 in different CML cell lines
Published in Anti-cancer agents in medicinal chemistry (01-01-2015)“…Chronic myeloid leukemia (CML), a myeloproliferative disorder characterized by the BCR-ABL oncoprotein, presents its treatment based on tyrosine kinase…”
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Extracellular Vesicle - MDM2-DNA as a Potential Liquid Biopsy Biomarker for Disease Identification in Retroperitoneal Liposarcoma
Published in Annals of surgery (21-05-2024)“…We aimed to assess the levels of MDM2-DNA within extracellular vesicles (EVs) isolated from the serum of retroperitoneal liposarcoma (RLS) patients versus…”
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LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells
Published in Oncology reports (01-01-2020)“…Glioblastoma (GBM) is the most frequent malignant brain tumor. It represents the most aggressive astrocytoma with an overall survival of 14 months. Despite…”
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In situ hybridization to detect DNA amplification in extracellular vesicles
Published in Journal of extracellular vesicles (01-09-2022)“…EVs have emerged as an important component in tumour initiation, progression and metastasis. Although notable progresses have been made, the detection of EV…”
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7
Preclinical efficacy of the Wnt/[beta]-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors
Published in PloS one (14-10-2022)“…Mutation in the CTNNB1 gene, leading to a deregulation of the WTN/[beta]-catenin pathway, is a common feature of desmoid tumors (DTs). Many [beta]-catenin…”
Get full text
Journal Article -
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Abstract A054: Oncogenic functions of alternatively spliced MDM2-ALT2 isoform in retroperitoneal liposarcoma
Published in Clinical cancer research (13-11-2024)“…Retroperitoneal liposarcoma (RPLPS) is one of the most common histologic subtypes of soft tissue sarcoma (STS). Complete surgical resection remains the…”
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Journal Article -
9
Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors
Published in PloS one (01-01-2022)“…Mutation in the CTNNB1 gene, leading to a deregulation of the WTN/β-catenin pathway, is a common feature of desmoid tumors (DTs). Many β-catenin inhibitors…”
Get full text
Journal Article