Search Results - "de Fabregues, Oriol"
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The Onset of Nonmotor Symptoms in Parkinson's disease (The ONSET PD Study)
Published in Movement disorders (01-02-2015)“…ABSTRACT Nonmotor symptoms (NMS) in Parkinson's disease (PD) can precede onset of motor symptoms. Relationship between premotor symptoms onset and motor…”
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2
Sleep Disorders in Parkinsonian and Nonparkinsonian LRRK2 Mutation Carriers
Published in PloS one (15-07-2015)“…In idiopathic Parkinson disease (IPD) sleep disorders are common and may antedate the onset of parkinsonism. Based on the clinical similarities between IPD and…”
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3
Relevance of tissue-resident memory CD8 T cells in the onset of Parkinson’s disease and examination of its possible etiologies: infectious or autoimmune?
Published in Neurobiology of disease (15-10-2023)“…Tissue-resident memory CD8 T cells are responsible for local immune surveillance in different tissues, including the brain. They constitute the first line of…”
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4
Pleuropulmonary Toxicity of Another Anti-Parkinson's Drug: Cabergoline
Published in The open respiratory medicine journal (05-06-2009)“…Many drugs may cause toxic injury to the lungs and the pleura. Cabergoline is an ergoline derivative which has been used in Spain for seven years to control…”
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Cerebrospinal fluid cytokines in multiple system atrophy: A cross-sectional Catalan MSA registry study
Published in Parkinsonism & related disorders (01-08-2019)“…Neuroinflammation is a potential player in neurodegenerative conditions, particularly the aggressive ones, such as multiple system atrophy (MSA). Previous…”
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Discovering the 3' UTR-mediated regulation of alpha-synuclein
Published in Nucleic acids research (15-12-2017)“…Recent evidence indicates a link between Parkinson's Disease (PD) and the expression of a-synuclein (SNCA) isoforms with different 3' untranslated regions…”
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Ammonium tetrathiomolybdate in the decoppering phase treatment of Wilson's disease with neurological symptoms: A case series
Published in Brain and behavior (01-05-2020)“…Objectives To present our experience with ammonium tetrathiomolybdate (ATTM) in the decoppering phase treatment of Wilson's disease (WD) with neurological…”
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An Observational Study of the Effect of Levodopa–Carbidopa Intestinal Gel on Activities of Daily Living and Quality of Life in Advanced Parkinson’s Disease Patients
Published in Advances in therapy (01-07-2017)“…Introduction Continuous delivery of levodopa–carbidopa intestinal gel (LCIG) by percutaneous endoscopic gastrojejunostomy (PEG-J) in advanced Parkinson’s…”
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Long‐term safety and effectiveness of levodopa‐carbidopa intestinal gel infusion
Published in Brain and behavior (01-08-2017)“…Introduction Levodopa‐carbidopa intestinal gel (LCIG) infusion has demonstrated to improve motor fluctuations. The aim of this study is to assess the long‐term…”
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10
Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson’s Disease: A Pilot Study
Published in Parkinson's disease (01-01-2018)“…Background. Sleep problems in patients with advanced Parkinson’s disease (PD) have a deleterious impact on quality of life. Objective. To assess the effect of…”
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Subclinical affective and cognitive fluctuations in Parkinson's disease: a randomized double-blind double-dummy study of Oral vs. Intrajejunal Levodopa
Published in Journal of neurology (01-11-2020)“…Background Chronic levodopa treatment in Parkinson’s disease (PD) may promote undesirable motor and non-motor fluctuations. Compared to chronic oral levodopa…”
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Transcriptomic differences in MSA clinical variants
Published in Scientific reports (25-06-2020)“…Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with…”
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Levodopa-carbidopa intestinal gel in advanced Parkinson's: Final results of the GLORIA registry
Published in Parkinsonism & related disorders (01-12-2017)“…This registry evaluated the 24-month safety and efficacy of levodopa-carbidopa intestinal gel (LCIG) treatment in advanced Parkinson's disease (PD) patients…”
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14
Can suitable candidates for levodopa/carbidopa intestinal gel therapy be identified using current evidence?
Published in eNeurologicalSci (01-09-2017)“…Advanced Parkinson's disease (APD) is characterized by increased functional disability, caused by motor complications, the presence of axial symptoms, and…”
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α‐synuclein RT‐QuIC in cerebrospinal fluid of LRRK2‐linked Parkinson's disease
Published in Annals of clinical and translational neurology (01-06-2019)“…Background Leucine‐rich kinase 2 (LRRK2)‐linked Parkinson's disease (PD) is clinically indistinguishable from idiopathic PD (IPD). A pleiotropic neuropathology…”
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Increased homocysteine levels correlate with cortical structural damage in Parkinson's disease
Published in Journal of the neurological sciences (15-03-2022)“…Blood homocysteine appears to be increased in Parkinson's disease (PD) and may play a role in the development and progression of this disorder. However, the…”
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Effects of COVID -19 pandemic and lockdown on people with multiple system atrophy participating in a therapeutic education program
Published in Parkinsonism & related disorders (01-05-2021)Get full text
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In vivo cholinergic basal forebrain degeneration and cognition in Parkinson's disease: Imaging results from the COPPADIS study
Published in Parkinsonism & related disorders (01-07-2021)“…We aimed to assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in Parkinson's disease…”
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Delineating the motor phenotype of SGCE-myoclonus dystonia syndrome
Published in Parkinsonism & related disorders (01-11-2020)“…To perform phenotype and genotype characterization in myoclonus-dystonia patients and to validate clinical rating tools. Two movement disorders experts rated…”
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Smoking is associated with age at disease onset in Parkinson's disease
Published in Parkinsonism & related disorders (01-04-2022)“…Previous studies linked disease-progression variables such as age at onset or survival to both genetic, and non-genetic factors in Parkinson's disease (PD)…”
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