Search Results - "de Fátima Silva, Flaviane"
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Chronic low-dose glucocorticoid treatment increases subcutaneous abdominal fat, but not visceral fat, of male Wistar rats
Published in Life sciences (1973) (01-12-2017)“…Most studies developed to investigate the effects of glucocorticoids chronic treatment on white adipose tissue uses high doses of these hormones. This study…”
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2
Glucocorticoid modulates oxidative and thermogenic function of rat brown adipose tissue and human brown adipocytes
Published in Journal of cellular physiology (01-09-2024)“…Chronic and excessive glucocorticoid (GC) exposure can cause Cushing's syndrome, resulting in fat accumulation in selected body areas. Particularly in the…”
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3
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning
Published in Molecular metabolism (Germany) (01-08-2023)“…Norepinephrine stimulates the adipose tissue thermogenic program through a β-adrenergic receptor (βAR)–cyclic adenosine monophosphate (cAMP)–protein kinase A…”
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4
Decreased hepatic response to glucagon, adrenergic agonists, and cAMP in glycogenolysis, gluconeogenesis, and glycolysis in tumor‐bearing rats
Published in Journal of cellular biochemistry (01-09-2018)“…The response to glucagon and adrenaline in cancer cachexia is poorly known. The aim of this study was to investigate the response to glucagon, adrenergic…”
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5
Oral β-hydroxybutyrate increases ketonemia, decreases visceral adipocyte volume and improves serum lipid profile in Wistar rats
Published in Nutrition & metabolism (24-04-2017)“…Ketosis can be induced in humans and in animals by fasting or dietary interventions, such as ketogenic diets. However, the increasing interest on the ketogenic…”
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6
Glucocorticoids contribute to metabolic and liver impairments induced by lactation overnutrition in male adult rats
Published in Frontiers in physiology (10-05-2023)“…Lactation overnutrition is a programming agent of energy metabolism, and litter size reduction leads to the early development of obesity, which persists until…”
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7
Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats
Published in Frontiers in physiology (08-05-2018)“…Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is…”
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8
Effects of metformin on insulin resistance and metabolic disorders in tumor-bearing rats with advanced cachexia
Published in Canadian journal of physiology and pharmacology (01-05-2018)“…Metformin (MET) is widely used in the correction of insulin (INS) resistance and metabolic abnormalities in type 2 diabetes. However, its effect on INS…”
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Dexamethasone-Induced Adipose Tissue Redistribution and Metabolic Changes: Is Gene Expression the Main Factor? An Animal Model of Chronic Hypercortisolism
Published in Biomedicines (01-09-2022)“…Chronic hypercortisolism has been associated with the development of several metabolic alterations, mostly caused by the effects of chronic glucocorticoid (GC)…”
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10
Celecoxib and Ibuprofen Restore the ATP Content and the Gluconeogenesis Activity in the Liver of Walker-256 Tumor-Bearing Rats
Published in Cellular physiology and biochemistry (01-01-2015)“…Background/Aims: The main purpose of this study was to investigate the effects of celecoxib and ibuprofen, both non-steroidal anti-inflammatory drugs (NSAIDs),…”
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11
Long-term glucocorticoid infusion impairs epididymal adipocyte metabolism and maturation and affects miR-150–5p actions
Published in Molecular and cellular endocrinology (01-08-2024)“…The most common form of hypercortisolism is iatrogenic Cushing's syndrome. Lipodystrophy and metabolic disorders can result from the use of exogenous…”
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12
Akt activation by insulin treatment attenuates cachexia in Walker‐256 tumor‐bearing rats
Published in Journal of cellular biochemistry (01-11-2020)“…Cancer‐bearing often exhibits hypoinsulinemia, insulin (INS) resistance and glutamine depletion associated with cachexia. However, INS and glutamine effects on…”
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13
Physiological concentrations of β-hydroxybutyrate do not promote adipocyte browning
Published in Life sciences (1973) (01-09-2019)“…Previous work has demonstrated that ketogenic diets promote white fat browning; however, the exact mechanisms underlying this phenomenom have yet to be…”
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14
Pioglitazone improves insulin sensitivity and reduces weight loss in Walker-256 tumor-bearing rats
Published in Life sciences (1973) (15-02-2017)“…The lipogenic effect of pioglitazone (PGZ), an insulin (INS) sensitizer, is well established. However, few studies have evaluated PGZ effects in preventing…”
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15
Intrauterine food restriction impairs the lipogenesis process in the mesenteric adipocytes from low-birth-weight rats into adulthood
Published in Frontiers in endocrinology (Lausanne) (2023)“…Intrauterine food restriction (IFR) during pregnancy is associated with low birth weight (LBW) and obesity in adulthood. It is known that white adipose tissue…”
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16
Effects of celecoxib and ibuprofen on metabolic disorders induced by Walker-256 tumor in rats
Published in Molecular and cellular biochemistry (01-01-2015)“…The contribution of anti-inflammatory property of celecoxib in the improvement of metabolic disorders in cancer is unknown. The purpose of this study was to…”
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Insulin, not glutamine dipeptide, reduces lipases expression and prevents fat wasting and weight loss in Walker 256 tumor-bearing rats
Published in European journal of pharmacology (05-07-2017)“…Cachexia is the main cause of mortality in advanced cancer patients. We investigated the effects of insulin (INS) and glutamine dipeptide (GDP), isolated or…”
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18
Inhibitory effect of tumor necrosis factor α on gluconeogenesis in perfused rat liver
Published in Molecular and cellular biochemistry (01-03-2013)“…Tumor necrosis factor α (TNFα) is a cytokine involved in many metabolic responses in both normal and pathological states. Considering that the effects of TNFα…”
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19
Fat Redistribution in an Experimental Model of Hypercortisolism in Rats
Published in The FASEB journal (01-04-2018)“…Chronic iatrogenic hypercortisolism, which is associated with the inhibition of the adrenal‐pituitary‐ hypothalamic axis, shows characteristic signs that are…”
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Inhibitory effect of tumor necrosis factor [alpha] on gluconeogenesis in perfused rat liver
Published in Molecular and cellular biochemistry (01-03-2013)“…Tumor necrosis factor [alpha] (TNF[alpha]) is a cytokine involved in many metabolic responses in both normal and pathological states. Considering that the…”
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