Search Results - "de Cristofaro, Tiziana"
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Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses
Published in International journal of genomics (01-01-2017)“…Dosage-dependent upregulation of most of chromosome 21 (Hsa21) genes has been demonstrated in heart tissues of fetuses with Down syndrome (DS). Also miRNAs…”
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Rise and fall of the materiality matrix: Lessons from a missed takeoff
Published in Administrative sciences (01-12-2022)“…After a long period of the inclusion of materiality matrices within standard setters documents and non-financial reports, the Global Reporting Initiative…”
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3
Long Non-Coding RNA HAND2-AS1 Acts as a Tumor Suppressor in High-Grade Serous Ovarian Carcinoma
Published in International journal of molecular sciences (05-06-2020)“…Long non-coding RNAs (lncRNAs) are increasingly being identified as crucial regulators in pathologies like cancer. High-grade serous ovarian carcinoma (HGSC)…”
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4
NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome
Published in Human molecular genetics (15-08-2014)“…Mitochondrial dysfunction, which is consistently observed in Down syndrome (DS) cells and tissues, might contribute to the severity of the DS phenotype. Our…”
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5
Variable levels of spike and ORF1ab RNA in post-mortem lung samples of SARS-CoV-2-positive subjects: comparison between ISH and RT-PCR
Published in Virchows Archiv : an international journal of pathology (01-03-2022)“…Post-mortem examination plays a pivotal role in understanding the pathobiology of the SARS-CoV-2; thus, the optimization of virus detection on the post-mortem…”
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A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells
Published in BMC cancer (26-04-2014)“…PAX8 is a member of the paired box (Pax) multigene family of transcription factors, which are involved in the developmental and tissue-specific control of the…”
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Loss of Detection of sgN Precedes Viral Abridged Replication in COVID-19-Affected Patients-A Target for SARS-CoV-2 Propagation
Published in International journal of molecular sciences (09-02-2022)“…The development of prophylactic agents against the SARS-CoV-2 virus is a public health priority in the search for new surrogate markers of active virus…”
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PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3
Published in Cancer cell international (20-11-2019)“…Ovarian cancer is the third most common cause of death among gynecologic malignancies worldwide. Understanding the biology and molecular pathogenesis of…”
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Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis
Published in PloS one (23-09-2011)“…The differentiation program of thyroid follicular cells (TFCs), by far the most abundant cell population of the thyroid gland, relies on the interplay between…”
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TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation
Published in Experimental cell research (15-01-2009)“…Pax8 and TTF-1 are transcription factors involved in the morphogenesis of the thyroid gland and in the transcriptional regulation of thyroid-specific genes…”
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Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene
Published in BMC genomics (14-05-2010)“…The molecular mechanisms leading to a fully differentiated thyrocite are still object of intense study even if it is well known that thyroglobulin,…”
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12
Pax8 protein stability is controlled by sumoylation
Published in Journal of molecular endocrinology (01-01-2009)“…The transcription factor Pax8 is involved in the morphogenesis of the thyroid gland and in the maintenance of the differentiated thyroid phenotype. Despite the…”
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13
Essential Role of A-kinase Anchor Protein 121 for cAMP Signaling to Mitochondria
Published in The Journal of biological chemistry (07-02-2003)“…A-Kinase anchor proteins (AKAPs) immobilize and concentrate protein kinase A (PKA) isoforms at specific subcellular compartments. Intracellular targeting of…”
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14
Poly(ADP-ribose) polymerase 1 binds to Pax8 and inhibits its transcriptional activity
Published in Journal of molecular endocrinology (01-11-2008)“…Pax8 is a transcription factor that plays an important role in the regulation of genes that are exclusively expressed in differentiated thyroid cells. In the…”
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15
Performance analysis and clustering of Italian SA8000-certified food and beverages companies
Published in British food journal (1966) (21-03-2023)“…PurposeThis work aims at discovering the multifaceted business performance of SA8000-certified companies operating in the Italian food and beverages…”
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16
High levels of adhesion molecules are associated with impaired endothelium-dependent vasodilation in patients with peripheral arterial disease
Published in Thrombosis and haemostasis (01-01-2001)“…Soluble intercellular adhesion molecule-1 (sICAM-1) and vascular cellular adhesion molecule-1 (sVCAM-1) were measured alongside flow-mediated vasodilation…”
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Long Non-Coding RNA MAGI2-AS3 is a New Player with a Tumor Suppressive Role in High Grade Serous Ovarian Carcinoma
Published in Cancers (12-12-2019)“…High-Grade Serous Ovarian Carcinoma (HGSC) is the most incidental and lethal subtype of epithelial ovarian cancer (EOC) with a high mortality rate of nearly…”
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PAX8, an Emerging Player in Ovarian Cancer
Published in Advances in experimental medicine and biology (01-01-2021)“…Ovarian Cancer is one of the most lethal and widespread gynecological malignancies. It is the seventh leading cause of all cancer deaths worldwide. High-Grade…”
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The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses
Published in The Journal of biological chemistry (04-08-2017)“…Inflammatory responses are elicited through lipid products of phospholipase A2 activity that acts on the membrane phospholipids, including the…”
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Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma
Published in Oncotarget (05-07-2016)“…Understanding the biology and molecular pathogenesis of ovarian epithelial cancer (EOC) is key to developing improved diagnostic and prognostic indicators and…”
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