Search Results - "de Crescenzo, A."
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Whole-body MRI with diffusion-weighted imaging: a valuable alternative to contrast-enhanced CT for initial staging of aggressive lymphoma
Published in Clinical radiology (01-03-2016)“…Aim To compare the accuracy of whole-body magnetic resonance imaging (Wb-MRI) with diffusion-weighted imaging (DWI) to that of contrast-enhanced computed…”
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Fetal growth patterns in Beckwith-Wiedemann syndrome
Published in Clinical genetics (01-07-2016)“…We provide data on fetal growth pattern on the molecular subtypes of Beckwith–Wiedemann syndrome (BWS): IC1 gain of methylation (IC1‐GoM), IC2 loss of…”
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A case of Beckwith-Wiedemann syndrome caused by a cryptic 11p15 deletion encompassing the centromeric imprinted domain of the BWS locus
Published in Journal of medical genetics (01-06-2010)“…BACKGROUND Beckwith-Wiedemann syndrome (BWS) is a clinically variable and genetically heterogeneous disorder, providing evidence that imprinted genes play key…”
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Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease
Published in Bioorganic & medicinal chemistry (03-11-2003)“…The human immunodeficiency virus (HIV) has been shown to be the causative agent for AIDS. The HIV virus encodes for a unique aspartyl protease that is…”
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Synthesis and activity of selective MMP inhibitors with an aryl backbone
Published in Bioorganic & medicinal chemistry letters (18-12-2000)“…A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described…”
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Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Published in Biochimica et biophysica acta (29-07-2002)“…MMP-2 is a member of the matrix metalloproteinase family that has been implicated in tumor cell metastasis and angiogenesis. Here, we describe the solution…”
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22q11.2 Distal Deletion Syndrome: Description of a New Case with Truncus Arteriosus Type 2 and Review
Published in Molecular syndromology (01-12-2011)“…22q11.2 deletion syndrome is mainly characterized by conotruncal congenital heart defects, velopharyngeal insufficiency, hypocalcemia and a characteristic…”
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Selective, orally active MMP inhibitors with an aryl backbone
Published in Bioorganic & medicinal chemistry letters (17-09-2001)“…This letter describes SAR exploration and rat PK optimization of a series of novel, MMP-1 sparing aryl hydroxamate sulfonamides with activity against MMP-2 and…”
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Prevalence of beckwith-wiedemann syndrome in North West of Italy
Published in American journal of medical genetics. Part A (01-10-2013)“…ABSTRACT Although Beckwith–Wiedemann syndrome (BWS, OMIM #130650) is the most common genetic overgrowth disorder, data on its epidemiology are scanty and the…”
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Silver-Russell syndrome due to paternal H19/IGF2 hypomethylation in a twin girl born after in vitro fertilization
Published in American journal of medical genetics. Part A (01-10-2013)“…ABSTRACT Silver–Russell syndrome (SRS) is a clinically and genetically heterogeneous syndrome characterized by severe intrauterine and postnatal growth…”
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Different mechanisms cause imprinting defects at the IGF2/H19 locus in Beckwith–Wiedemann syndrome and Wilms' tumour
Published in Human molecular genetics (15-05-2008)“…The parent of origin-dependent expression of the IGF2 and H19 genes is controlled by the imprinting centre 1 (IC1) consisting in a methylation-sensitive…”
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Combined modality treatment with a weekly brief chemotherapy (ACOP-B) followed by locoregional radiotherapy in localized-stage intermediate- to high-grade non-Hodgkin's lymphoma
Published in Annals of oncology (01-11-1996)“…Background: A cooperative study was undertaken to evaluate the efficacy and toxicity of a very brief course of chemotherapy followed by locoregional…”
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Tween-20 Activates and Solubilizes the Mitochondrial Membrane-bound, Calmodulin Dependent NAD + Kinase of Avena sativa L
Published in The Journal of membrane biology (15-07-2001)Get full text
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Prognostic significance of serum albumin in chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-03-1991)“…Low levels of serum albumin have been reported to be associated with a poor prognosis in lymphoproliferative disorders. Clinical and laboratory data were…”
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High rate of clinical and molecular remissions in follicular lymphoma patients receiving high-dose sequential chemotherapy and autografting at diagnosis: a multicenter, prospective study by the Gruppo Italiano Trapianto Midollo Osseo (GITMO)
Published in Blood (01-09-2002)“…Single-center experiences have shown that intensified treatments with autologous transplantation are a promising therapeutic strategy for patients with…”
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High-dose sequential chemotherapy and peripheral blood progenitor cell autografting in patients with refractory and/or recurrent Hodgkin lymphoma: A multicenter study of the Intergruppo Italiano Linfomi showing prolonged disease free survival in patients treated at first recurrence
Published in Cancer (01-06-2003)“…The objective of the current study was to evaluate in a multicenter setting the feasibility and efficacy of a high-dose sequential (HDS) chemotherapy regimen…”
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Evidence of active NADP+ phosphatase in dormant seeds of Avena sativa L
Published in Journal of experimental botany (01-08-2000)“…Freshly‐harvested seeds of Avena sativa L. do not germinate when imbibed at temperatures higher than 25 °C. This high temperature dormancy is due to the seed…”
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Feasibility and long-term results of autologous PBSC transplantation in recurrent undifferentiated nasopharyngeal carcinoma
Published in Head & neck (01-09-2001)“…Background Recurrent undifferentiated nasopharyngeal carcinoma (UNPC) is a chemosensitive illness. Here we report long‐term results of high‐dose chemotherapy…”
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