Search Results - "de Chaffoy, Didier"

Synthesis and biological evaluation of imidazol-2-one and 2-cyanoiminoimidazole derivatives: novel series of PDE4 inhibitors by Andrés, J.Ignacio, Alonso, José M, Dı́az, Adolfo, Fernández, Javier, Iturrino, Laura, Martı́nez, Pedro, Matesanz, Encarna, Freyne, Eddy J, Deroose, Frederik, Boeckx, Gustaaf, Petit, Davy, Diels, Gaston, Megens, Anton, Somers, Marijke, Wauwe, Jean Van, Stoppie, Paul, Cools, Marina, Clerck, Fred De, Peeters, Danielle, de Chaffoy, Didier

“…This communication describes the synthesis and in vitro PDE4 inhibitory activity of a novel series of imidazol-2-one and 2-cyanoiminoimidazole derivatives. The…”
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Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis by Andries, Koen, Verhasselt, Peter, Guillemont, Jerome, Göhlmann, Hinrich W. H, Neefs, Jean-Marc, Winkler, Hans, Van Gestel, Jef, Timmerman, Philip, Zhu, Min, Lee, Ennis, Williams, Peter, de Chaffoy, Didier, Huitric, Emma, Hoffner, Sven, Cambau, Emmanuelle, Truffot-Pernot, Chantal, Lounis, Nacer, Jarlier, Vincent

“…The incidence of tuberculosis has been increasing substantially on a worldwide basis over the past decade, but no tuberculosis-specific drugs have been…”
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The synergistic effect of 5-hydroxytryptamine and epinephrine on the human platelet is related to the activation of phospholipase C by Roevens, P, De Clerck, F, de Chaffoy de Courcelles, D

“…Simultaneous addition of 5-hydroxytryptamine (5-HT) and epinephrine synergistically elevated cytosolic free Ca2+ concentration ([Ca2+]cyt) and activated…”
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Is there evidence of a role of the phosphoinositol-cycle in the myocardium? by de Chaffoy de Courcelles, D

“…The recent findings on a more general involvement of phospholipids in signal transduction and on the different roles of inositolphospholipids in particular,…”
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Ouabain Increases the Calcium Concentration in Intracellular Stores Involved in Stimulus-Response Coupling in Human Platelets by Roevens, Peter, de Chaffoy de Courcelles, Didier

“…The effect of ouabain on Ca homeostasis in human platelets was studied using both quin 2 and chlorotetracycline to monitor changes in cytosolic Ca as well as…”
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Functional expression of the amplification reaction between serotonin and epinephrine on platelets by De Clerck, F, Xhonneux, B, de Chaffoy de Courcelles, D

“…Human platelet reactions are enhanced when a combination of serotonin and epinephrine is used as a stimulus. The amplification of the response operates through…”
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Effect of thromboxane A2 synthetase inhibition, singly and combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on inositol phospholipid turnover and on 5-HT release by washed human platelets by de Chaffoy de Courcelles, D, De Clerck, F

“…Differential effects on human platelet function of thromboxane A2 (TXA2) synthetase inhibition singly and of TXA2 synthetase inhibition combined with…”
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Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties by Schneider, J, Beck, E, Heers, C, Conrad, C, de Chaffoy de Courcelles, D, Wilffert, B, Peters, T

“…R 79595 (N-cyclohexyl-N-methyl-2-[[[phenyl (1,2,3,5-tetrahydro-2 oxoimidazo [2,1-b]-quinazolin-7-yl) methylene] amin] oxy] acetamide) and its isomers represent…”
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Serotonin-induced alterations in inositol phospholipid metabolism in human platelets by de Chaffoy de Courcelles, D, Roevens, P, Wynants, J, Van Belle, H

“…When human platelets were incubated for 5 min with [32P]orthophosphate and then stimulated with serotonin, the 32P content of phosphatidylinositol (PI)…”
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The synergistic effect of serotonin and epinephrine at the level of signal transduction by de Chaffoy de Courcelles, D, Roevens, P, De Clerck, F

“…Evidence is presented of synergistic interactions occurring between serotonin and epinephrine at the level of signal transduction. Different mechanisms that…”
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THE ARTEMIA SALINA LIPOVITELLINE COMPLEX (DUTCH TEXT) by DE CHAFFOY DE COURCELLES, DIDIER ROBERT GUY GABRIELLE

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