Serratia marcescens harboring SME-4 in Brazil: a silent threat

Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their con...

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Bibliographic Details
Published in:	Diagnostic microbiology and infectious disease Vol. 87; no. 4; pp. 357 - 358
Main Authors:	Cayô, Rodrigo, Leme, Rodrigo Cuiabano Paes, Streling, Ana Paula, Matos, Adriana Pereira, Nodari, Carolina Silva, Chaves, Jessica Reis Esteves, Brandão, Jorge Luiz Ferreira, de Almeida, Maíra Fernandes, Carrareto, Valério, de Castro Pereira, Marco Aurélio, de Almeida, Jean Pierre Aquino, Ferreira, Demian Candido, Gales, Ana Cristina
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-04-2017
Subjects:	Anti-Bacterial Agents - therapeutic use Bacterial Proteins - metabolism beta-Lactamases - metabolism Brazil Carbapenem resistance Catheter-related bloodstream infection Class A carbapenemase Drug Resistance, Bacterial - drug effects Enterobacteriaceae Female Humans Infectious Disease Internal Medicine Microbial Sensitivity Tests Middle Aged Septic shock Serine carbapenemase Serratia Serratia Infections - drug therapy Serratia Infections - microbiology Serratia marcescens - isolation & purification Serratia marcescens - metabolism Class A carbapenemase Septic shock Carbapenem resistance Serine carbapenemase Serratia Enterobacteriaceae Catheter-related bloodstream infection
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Summary:	Abstract The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their consequent spread in our territory is noteworthy.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2017.01.008