Search Results - "de Cassan, C."

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens by Illingworth, Joseph J, Alanine, Daniel G, Brown, Rebecca, Marshall, Jennifer M, Bartlett, Helen E, Silk, Sarah E, Labbé, Geneviève M, Quinkert, Doris, Cho, Jee Sun, Wendler, Jason P, Pattinson, David J, Barfod, Lea, Douglas, Alexander D, Shea, Michael W, Wright, Katherine E, de Cassan, Simone C, Higgins, Matthew K, Draper, Simon J

“…The malaria genome encodes over 5,000 proteins and many of these have also been proposed to be potential vaccine candidates, although few of these have been…”
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Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure by Biswas, Sumi, Choudhary, Prateek, Elias, Sean C, Miura, Kazutoyo, Milne, Kathryn H, de Cassan, Simone C, Collins, Katharine A, Halstead, Fenella D, Bliss, Carly M, Ewer, Katie J, Osier, Faith H, Hodgson, Susanne H, Duncan, Christopher J A, O'Hara, Geraldine A, Long, Carole A, Hill, Adrian V S, Draper, Simon J

“…The development of protective vaccines against many difficult infectious pathogens will necessitate the induction of effective antibody responses. Here we…”
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Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial by Hodgson, Susanne H, Choudhary, Prateek, Elias, Sean C, Milne, Kathryn H, Rampling, Thomas W, Biswas, Sumi, Poulton, Ian D, Miura, Kazutoyo, Douglas, Alexander D, Alanine, Daniel GW, Illingworth, Joseph J, de Cassan, Simone C, Zhu, Daming, Nicosia, Alfredo, Long, Carole A, Moyle, Sarah, Berrie, Eleanor, Lawrie, Alison M, Wu, Yimin, Ellis, Ruth D, Hill, Adrian V S, Draper, Simon J

“…The development of effective vaccines against difficult disease targets will require the identification of new subunit vaccination strategies that can induce…”
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Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines by Draper, Simon J, Biswas, Sumi, Spencer, Alexandra J, Remarque, Edmond J, Capone, Stefania, Naddeo, Mariarosaria, Dicks, Matthew D J, Faber, Bart W, de Cassan, Simone C, Folgori, Antonella, Nicosia, Alfredo, Gilbert, Sarah C, Hill, Adrian V S

“…Protein-in-adjuvant formulations and viral-vectored vaccines encoding blood-stage malaria Ags have shown efficacy in rodent malaria models and in vitro assays…”
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Recent advances in antibody-inducing poxviral and adenoviral vectored vaccine delivery platforms for difficult disease targets by de Cassan, Simone C, Draper, Simon J

“…Viral vectored vaccine delivery platforms have traditionally been used for the induction of cellular rather than humoral immunity. However, in recent years,…”
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Analysis of human B‐cell responses following ChAd63‐MVA MSP1 and AMA1 immunization and controlled malaria infection by Elias, Sean C., Choudhary, Prateek, Cassan, Simone C., Biswas, Sumi, Collins, Katharine A., Halstead, Fenella D., Bliss, Carly M., Ewer, Katie J., Hodgson, Susanne H., Duncan, Christopher J. A., Hill, Adrian V. S., Draper, Simon J.

“…Summary Acquisition of non‐sterilizing natural immunity to Plasmodium falciparum malaria has been shown in low transmission areas following multiple exposures…”
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Preclinical Assessment of Viral Vectored and Protein Vaccines Targeting the Duffy-Binding Protein Region II of Plasmodium Vivax by de Cassan, Simone C, Shakri, A Rushdi, Llewellyn, David, Elias, Sean C, Cho, Jee Sun, Goodman, Anna L, Jin, Jing, Douglas, Alexander D, Suwanarusk, Rossarin, Nosten, François H, Rénia, Laurent, Russell, Bruce, Chitnis, Chetan E, Draper, Simon J

“…Malaria vaccine development has largely focused on Plasmodium falciparum; however, a reawakening to the importance of Plasmodium vivax has spurred efforts to…”
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The natural history of gastro-esophageal reflux disease: a comprehensive review by Savarino, E., de Bortoli, N., De Cassan, C., Della Coletta, M., Bartolo, O., Furnari, M., Ottonello, A., Marabotto, E., Bodini, G., Savarino, V.

“…SUMMARY Gastroesophageal reflux disease (GERD) is a common disorder of the upper gastrointestinal tract which is typically characterized by heartburn and acid…”
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Esophagogastric junction contractility for clinical assessment in patients with GERD: a real added value? by Tolone, S., De Bortoli, N., Marabotto, E., Cassan, C., Bodini, G., Roman, S., Furnari, M., Savarino, V., Docimo, L., Savarino, E.

“…Background The role of esophagogastric junction contractile integral (EGJ‐CI) as assessed by high‐resolution manometry (HRM) is unclear. We aimed to correlate…”
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Assessment of antibody-dependent respiratory burst activity from mouse neutrophils on Plasmodium yoelii malaria challenge outcome by Llewellyn, David, Cassan, Simone C., Williams, Andrew R., Douglas, Alexander D., Forbes, Emily K., Adame‐Gallegos, Jaime R., Shi, Jianguo, Pleass, Richard J., Draper, Simon J.

“…Malaria‐specific antibody‐dependent respiratory burst activity from neutrophils is acquired in mice following infection; however, vaccination with a leading…”
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T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein by Forbes, Emily K, de Cassan, Simone C, Llewellyn, David, Biswas, Sumi, Goodman, Anna L, Cottingham, Matthew G, Long, Carole A, Pleass, Richard J, Hill, Adrian V S, Hill, Fergal, Draper, Simon J

“…Viral vectored vaccines have been shown to induce both T cell and antibody responses in animals and humans. However, the induction of even higher level T cell…”
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Esophagogastric junction morphology is associated with a positive impedance‐pH monitoring in patients with GERD by Tolone, S., Cassan, C., Bortoli, N., Roman, S., Galeazzi, F., Salvador, R., Marabotto, E., Furnari, M., Zentilin, P., Marchi, S., Bardini, R., Sturniolo, G. C., Savarino, V., Savarino, E.

“…Background High‐resolution manometry (HRM) provides information on esophagogastric junction (EGJ) morphology, distinguishing three different subtypes. Data on…”
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Investigating the Induction of Vaccine-Induced Th17 and Regulatory T Cells in Healthy, Mycobacterium bovis BCG-Immunized Adults Vaccinated with a New Tuberculosis Vaccine, MVA85A by de Cassan, Simone C, Pathan, Ansar A, Sander, Clare R, Minassian, Angela, Rowland, Rosalind, Hill, Adrian V S, McShane, Helen, Fletcher, Helen A

“…Errata ( vol. 18 , p. 696 ) Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment by Goodman, Anna L., Forbes, Emily K., Williams, Andrew R., Douglas, Alexander D., de Cassan, Simone C., Bauza, Karolis, Biswas, Sumi, Dicks, Matthew D. J., Llewellyn, David, Moore, Anne C., Janse, Chris J., Franke-Fayard, Blandine M., Gilbert, Sarah C., Hill, Adrian V. S., Pleass, Richard J., Draper, Simon J.

“…Rodent malaria species Plasmodium yoelii and P. chabaudi have been widely used to validate vaccine approaches targeting blood-stage merozoite antigens…”
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The GerdQ questionnaire and high resolution manometry support the hypothesis that proton pump inhibitor‐responsive oesophageal eosinophilia is a GERD‐related phenomenon by Savarino, E. V., Tolone, S., Bartolo, O., de Cassan, C., Caccaro, R., Galeazzi, F., Nicoletti, L., Salvador, R., Martinato, M., Costantini, M., Savarino, V.

“…Summary Background Little is known about the relationship between proton pump inhibitor‐responsive oesophageal eosinophilia (PPI‐REE), eosinophilic esophagitis…”
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Letter: biological therapies are effective for prevention of post‐operative Crohn's disease recurrence by Bodini, G., De Cassan, C., Savarino, V., Savarino, E.

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P.08.12 GERDQ QUESTIONNAIRE DISTINGUISHES PROTON PUMP INHIBITOR-RESPONSIVE ESOPHAGEAL EOSINOPHILIA FROM EOSINOPHILIC ESOPHAGITIS PATIENTS by Bartolo, O, De Cassan, C, Galeazzi, F, Tolone, S, Salvador, R, Sturniolo, G.C, Costantini, M, Savarino, E

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P.06.12 GRANULO-MONOCYTOAPHERESIS IS MORE EFFECTIVE IN INDUCING AND MAINTAINING CLINICAL RESPONSE IN MILD ULCERATIVE COLITIS THAN IN MODERATE TO SEVERE DISEASE by De Cassan, C, Savarino, E.V, Marson, P, Hatem, G, Sturniolo, G.C, D'Incà, R

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P.06.13 MAINTENANCE GRANULO-MONOCYTOAPHERESIS IS EFFECTIVE IN INDUCING AND MAINTAINING CLINICAL RESPONSE IN MILD ULCERATIVE COLITIS by De Cassan, C, Savarino, E.V, Tison, T, Hatem, G, Sturniolo, G.C, D'Incà, R

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P.12.23 DIAGNOSTIC ACCURACY OF MMX-MB PANCHROMOCOLONOSCOPY IN PIT PATTERN ASSESSMENT AND CHARACTERIZATION OF NEOPLASTIC AND NON-NEOPLASTIC COLONIC LESIONS (PRELIMINARY DATA) by Repici, A, Fini, L, Vitetta, E.M, Ferrara, E.C, De Cassan, C, Danese, S

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