Anti-müllerian hormone is the best predictor of poor response in ICSI cycles of patients with endometriosis

To correlate ovarian reserve (OR) markers with response in assisted reproduction techniques (ART) and determine their ability to predict poor response among patients with endometriosis (EDT). We evaluated ART cycles of 27 women with EDT and 50 with exclusive male factor. Basal follicle stimulating h...

Full description

Saved in:

Bibliographic Details
Published in:	Clinical and experimental obstetrics & gynecology Vol. 38; no. 2; pp. 119 - 122
Main Authors:	de Carvalho, B Ramalho, Rosa-e-Silva, A C Japur de Sá, Rosa-e-Silva, J C, dos Reis, R M, Ferriani, R A, de Sá, M F Silva
Format:	Journal Article
Language:	English
Published:	Canada 2011
Subjects:	Anti-Mullerian Hormone - blood Endometriosis - blood Endometriosis - complications Endometriosis - therapy Female Follicle Stimulating Hormone - blood Humans Infertility, Female - etiology Infertility, Male Male Ovary - physiology Ovulation Induction - methods ROC Curve Sperm Injections, Intracytoplasmic - methods
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	To correlate ovarian reserve (OR) markers with response in assisted reproduction techniques (ART) and determine their ability to predict poor response among patients with endometriosis (EDT). We evaluated ART cycles of 27 women with EDT and 50 with exclusive male factor. Basal follicle stimulating hormone (FSH) and anti-müllerian hormone (AMH) levels were determined. Ovarian response to gonadotropin stimulation was assessed and correlation coefficients calculated between the variables and reserve markers. Areas under the curve (AUC) determined ability of tests to predict poor response. AMH was significantly correlated with response in both groups and it was the only marker with significant discriminative capacity to predict poor response among EDT (AUC = 0.842; 95% CI: 0.651-0.952) and control group (AUC = 0.869; 95% CI: 0.743-0.947). Infertile patients with endometriosis can benefit from the pre-therapeutic assessment of OR markers. However, regardless of disease presence, only AMH predicts poor response to stimulus.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0390-6663