Search Results - "de Bruijn, Inge H Briaire"

No NFATC2 fusion in simple bone cyst of the jaw by Ong, Sheena L M, Gomes, Isadora P, Baelde, Hans J, Passador‐Santos, Fabricio, Andrade, Bruno A B, Briaire‐de Bruijn, Inge H, Cavalcante, Israel L, Schreuder, Willem H, Cleton‐Jansen, Anne‐Marie, Cleven, Arjen H G, Szuhai, Karoly, Gomes, Carolina C, Bovée, Judith V M G

“…Aims Simple Bone Cysts (SBCs) predominantly occur in long bones and 59% harbour NFATC2 rearrangements. Jaw SBC is rare and was previously referred to as…”
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NTRK fusions are extremely rare in bone tumours by Lam, Suk Wai, Briaire‐de Bruijn, Inge H, Wezel, Tom, Cleven, Arjen H G, Hogendoorn, Pancras C W, Cleton‐Jansen, Anne‐Marie, Bovée, Judith V M G

“…Aims Because of the efficacy of tropomyosin receptor kinase (Trk) inhibitor therapy in tumours with rearrangements of the neurotrophic tyrosine kinase receptor…”
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Multimodal Mass Spectrometry Imaging of N‑Glycans and Proteins from the Same Tissue Section by Heijs, Bram, Holst, Stephanie, Briaire-de Bruijn, Inge H., van Pelt, Gabi W., de Ru, Arnoud H., van Veelen, Peter A., Drake, Richard R., Mehta, Anand S., Mesker, Wilma E., Tollenaar, Rob A., Bovée, Judith V. M. G., Wuhrer, Manfred, McDonnell, Liam A.

“…On-tissue digestion matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can be used to record spatially correlated molecular…”
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Utility of FOS as diagnostic marker for osteoid osteoma and osteoblastoma by Lam, Suk Wai, Cleven, Arjen H. G., Kroon, Herman M., Briaire-de Bruijn, Inge H., Szuhai, Karoly, Bovée, Judith V. M. G.

“…Osteoid osteoma and osteoblastoma are bone-forming tumors shown to harbor FOS (87%) and FOSB (3%) rearrangements. The aim was to evaluate the…”
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The Variable Genomic Landscape During Osteosarcoma Progression: Insights From a Longitudinal WGS Analysis by Meijer, Debora M., Ruano, Dina, Briaire‐de Bruijn, Inge H., Wijers‐Koster, Pauline M., Sande, Michiel A. J., Gelderblom, Hans, Cleton‐Jansen, Anne‐Marie, Miranda, Noel F. C. C., Kuijjer, Marieke L., Bovée, Judith V. M. G.

“…ABSTRACT Osteosarcoma is a primary bone tumor that exhibits a complex genomic landscape characterized by gross chromosomal abnormalities. Osteosarcoma patients…”
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Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines by Suijker, Johnny, Oosting, Jan, Koornneef, Annemarie, Struys, Eduard A, Salomons, Gajja S, Schaap, Frank G, Waaijer, Cathelijn J F, Wijers-Koster, Pauline M, Briaire-de Bruijn, Inge H, Haazen, Lizette, Riester, Scott M, Dudakovic, Amel, Danen, Erik, Cleton-Jansen, Anne-Marie, van Wijnen, Andre J, Bovée, Judith V M G

“…Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are found in a subset of benign and malignant cartilage tumors, gliomas and leukaemias. The mutant…”
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Anti‐inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor‐treated gastrointestinal stromal tumors by van Dongen, Minka, Savage, Nigel D.L., Jordanova, Ekaterina S., Briaire‐de Bruijn, Inge H., Walburg, Kimberley V., Ottenhoff, Tom H.M., Hogendoorn, Pancras C.W., van der Burg, Sjoerd H., Gelderblom, Hans, van Hall, Thorbald

“…We have made a detailed inventory of the immune infiltrate of gastrointestinal stromal tumors (GISTs), which originate from mesenchymal cells in the intestinal…”
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Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas by van IJzendoorn, David G P, Szuhai, Karoly, Briaire-de Bruijn, Inge H, Kostine, Marie, Kuijjer, Marieke L, Bovée, Judith V M G

“…Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly…”
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Linkage-Specific in Situ Sialic Acid Derivatization for N‑Glycan Mass Spectrometry Imaging of Formalin-Fixed Paraffin-Embedded Tissues by Holst, Stephanie, Heijs, Bram, de Haan, Noortje, van Zeijl, René J. M, Briaire-de Bruijn, Inge H, van Pelt, Gabi W, Mehta, Anand S, Angel, Peggy M, Mesker, Wilma E, Tollenaar, Rob A, Drake, Richard R, Bovée, Judith V. M. G, McDonnell, Liam A, Wuhrer, Manfred

“…Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging is a rapidly evolving field in which mass spectrometry techniques are applied…”
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Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model by Palubeckaitė, Ieva, Venneker, Sanne, van den Akker, Brendy E. W. M., Briaire-de Bruijn, Inge H., Boveé, Judith V. M. G.

“…Chondrosarcomas are well known for their resistance to conventional chemotherapy and radiotherapy treatment regimens, which is particularly detrimental in…”
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Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4 by Martins-Neves, Sara R., Corver, Willem E., Paiva-Oliveira, Daniela I., van den Akker, Brendy E. W. M., Briaire-de-Bruijn, Inge H., Bovée, Judith V. M. G., Gomes, Célia M. F., Cleton-Jansen, Anne-Marie

“…Osteosarcoma is a bone tumor, displaying significant cellular and histological heterogeneity and a complex genetic phenotype. Although multiple studies…”
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Odontogenic Myxomas Harbor Recurrent Copy Number Alterations and a Distinct Methylation Signature by Kleijn, Tony G, Ameline, Baptiste, Schreuder, Willem H, Kooistra, Wierd, Doff, Jan J, Witjes, Max, Pichardo, Sarina E C, Lausová, Tereza, Koppes, Sjors A, van den Hout, Mari F C M, van Engen-van Grunsven, Ilse C H, Flucke, Uta E, de Lange, Jan, Szuhai, Karoly, Briaire-de Bruijn, Inge H, Savci-Heijink, Dilara C, Suurmeijer, Albert J H, Bovée, Judith V M G, von Deimling, Andreas, Baumhoer, Daniel, Cleven, Arjen H G

“…Odontogenic myxoma is a rare, benign, and locally aggressive tumor that develops in the tooth-bearing areas of the jaw. The molecular mechanisms underlying…”
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Molecular signatures of tumor progression in myxoid liposarcoma identified by N-glycan mass spectrometry imaging by Heijs, Bram, Holst-Bernal, Stephanie, de Graaff, Marieke A., Briaire-de Bruijn, Inge H., Rodriguez-Girondo, Mar, van de Sande, Michiel A.J., Wuhrer, Manfred, McDonnell, Liam A., Bovée, Judith V.M.G.

“…Myxoid liposarcoma (MLS) is the second most common subtype of liposarcoma, accounting for ~6% of all sarcomas. MLS is characterized by a pathognomonic…”
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Enchondromatosis (Ollier disease, Maffucci syndrome) is not caused by the PTHR1 mutation p.R150C by Rozeman, Leida B., Sangiorgi, Luca, Bruijn, Inge H. Briaire-de, Mainil-Varlet, Pierre, Bertoni, F., Cleton-Jansen, Anne Marie, Hogendoorn, Pancras C.W., Bovée, Judith V.M.G.

“…Enchondromatosis (Ollier disease, Maffucci syndrome) is a rare developmental disorder characterized by multiple enchondromas. Not much is known about its…”
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Cadherins are regulated by Ep-CAM via phosphaditylinositol-3 kinase by Winter, Manon J, Cirulli, Vincenzo, Briaire-de Bruijn, Inge H, Litvinov, Sergey V

“…The cross-signaling between (cell) adhesion molecules is nowadays a well-accepted phenomenon and includes orchestrated cellular changes and changes in the…”
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Beyond the Influence of IDH Mutations: Exploring Epigenetic Vulnerabilities in Chondrosarcoma by Venneker, Sanne, Kruisselbrink, Alwine B, Baranski, Zuzanna, Palubeckaite, Ieva, Briaire-de Bruijn, Inge H, Oosting, Jan, French, Pim J, Danen, Erik H J, Bovée, Judith V M G

“…Mutations in the isocitrate dehydrogenase ( or ) genes are common in enchondromas and chondrosarcomas, and lead to elevated levels of the oncometabolite…”
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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma by Kuijjer, Marieke L, Peterse, Elisabeth F P, van den Akker, Brendy E W M, Briaire-de Bruijn, Inge H, Serra, Massimo, Meza-Zepeda, Leonardo A, Myklebost, Ola, Hassan, A Bassim, Hogendoorn, Pancras C W, Cleton-Jansen, Anne-Marie

“…High-grade osteosarcoma is an aggressive tumor most often developing in the long bones of adolescents, with a second peak in the 5th decade of life. Better…”
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Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies by Kostine, Marie, Briaire-de Bruijn, Inge H., Cleven, Arjen H. G., Vervat, Carly, Corver, Willem E., Schilham, Marco W., Van Beelen, Els, van Boven, Hester, Haas, Rick L., Italiano, Antoine, Cleton-Jansen, Anne-Marie, Bovée, Judith V. M. G.

“…Background: Immunotherapy may be a rational strategy in leiomyosarcoma (LMS), a tumor known for its genomic complexity. As a prerequisite for therapeutic…”
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Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status by Venneker, Sanne, Kruisselbrink, Alwine B, Briaire-de Bruijn, Inge H, de Jong, Yvonne, van Wijnen, Andre J, Danen, Erik H J, Bovée, Judith V M G

“…Chondrosarcomas are chemo- and radiotherapy resistant and frequently harbor mutations in ( or ), causing increased levels of D-2-hydroxyglutarate (D-2-HG). DNA…”
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Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment by SCHRAGE, Yvonne M, BRIAIRE-DE BRUIJN, Inge H, DE MIRANDA, Noel F. C. C, VAN OOSTERWIJK, Jolieke, TAMINIAU, Antonie H. M, VAN WEZEL, Tom, HOGENDOORN, Pancras C. W, BOVEE, Judith V. M. G

“…Chondrosarcomas are notorious for their resistance to conventional chemotherapy and radiotherapy, indicating there are no curative treatment possibilities for…”
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