Search Results - "de Bruijn, H. S."

In vivo nonlinear spectral imaging in mouse skin by Palero, Jonathan A, de Bruijn, H S, van der Ploeg-van den Heuvel, A, Sterenborg, H J C M, Gerritsen, H C

“…We report on two-photon autofluorescence and second harmonic spectral imaging of live mouse tissues. The use of a high sensitivity detector and ultraviolet…”
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Monitoring In Situ Dosimetry and Protoporphyrin IX Fluorescence Photobleaching in the Normal Rat Esophagus During 5-Aminolevulinic Acid Photodynamic Therapy by Boere, I. A., Robinson, D. J., de Bruijn, H. S., van den Boogert, J., Tilanus, H. W., Sterenborg, H. J C. M., de Bruin, R. W F.

“…Experimental therapies for Barrett's esophagus, such as 5-aminolevulinic acid (ALA)–based photodynamic therapy (PDT), aim to ablate the premalignant Barrett's…”
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Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice by VAN DER VEEN, N, DE BRUIJN, H. S, BERG, R. J. W, STAR, W. M

“…In this study the kinetics and localisation of protoporphyrin IX (PpIX) fluorescence in skin and skin tumours were examined after topically (20% for 4h) or…”
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In vivo quantification of the scattering properties of tissue using multi-diameter single fiber reflectance spectroscopy by van Leeuwen-van Zaane, F, Gamm, U A, van Driel, P B A A, Snoeks, T J A, de Bruijn, H S, van der Ploeg-van den Heuvel, A, Mol, I M, Löwik, C W G M, Sterenborg, H J C M, Amelink, A, Robinson, D J

“…Multi diameter single fiber reflectance (MDSFR) spectroscopy is a non-invasive optical technique based on using multiple fibers of different diameters to…”
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Topical hexylaminolevulinate and aminolevulinic acid photodynamic therapy: Complete arteriole vasoconstriction occurs frequently and depends on protoporphyrin IX concentration in vessel wall by Middelburg, T.A., de Bruijn, H.S., Tettero, L., van der Ploeg van den Heuvel, A., Neumann, H.A.M., de Haas, E.R.M., Robinson, D.J.

“…•Vascular responses to topical HAL and ALA based PDT are not well known.•The vasculature was imaged using confocal microscopy in a mouse skin fold…”
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Evidence for an important role of neutrophils in the efficacy of photodynamic therapy in vivo by DE VREE, W. J. A, ESSERS, M. C, DE BRUIJN, H. S, STAR, W. M, KOSTER, J. F, SLUITER, W

“…To investigate the role of neutrophils in the efficacy of photodynamic therapy (PDT) in rhabdomyosarcoma-bearing rats, the number of these circulating…”
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The effect of fluence rate on the acute response of vessel diameter and red blood cell velocity during topical 5-aminolevulinic acid photodynamic therapy by van Leeuwen-van Zaane, F, de Bruijn, H.S, van der Ploeg-van den Heuvel, A, Sterenborg, H.J.M.C, Robinson, D.J

“…Summary Background In a previous study it is shown that for topically applied ALA-PDT, PpIX concentration correlates with vascular changes including…”
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Improvement of systemic 5-aminolevulinic acid-based photodynamic therapy in vivo using light fractionation with a 75-minute interval by DE BRUIJN, H. S, VAN DER VEEN, N, ROBINSON, D. J, STAR, W. M

“…We have studied different single and fractionated illumination schemes after systemic administration of 5-aminolevulinic acid (ALA) to Improve the response of…”
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The effect of light fractionation with a 2-h dark interval on the efficacy of topical hexyl-aminolevulinate photodynamic therapy in normal mouse skin by Middelburg, T.A., MD, de Bruijn, H.S, van der Ploeg-van den Heuvel, A, Neumann, H.A.M, Robinson, D.J

“…Summary Background Light fractionation with a 2-h dark interval increases the efficacy of topical aminolevulinic acid (ALA) photodynamic therapy (PDT)…”
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In vivo pharmacokinetics of protoporphyrin IX accumulation following intracutaneous injection of 5-aminolevulinic acid by de Blois, A.W., Thissen, M.R.T.M, de Bruijn, H.S., Grouls, R.J.E., Dutrieux, R.P., Robinson, D.J., Neumann, H.A.M.

“…Photodynamic therapy with 5-aminolevulinic acid (ALA) derived protoporphyrin IX (PpIX) as photosensitizer is a promising treatment for basal cell carcinomas…”
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Fractionated illumination after topical application of 5-aminolevulinic acid on normal skin of hairless mice: The influence of the dark interval by de Bruijn, H.S., van der Ploeg – van den Heuvel, A., Sterenborg, H.J.C.M., Robinson, D.J.

“…We have previously shown that light fractionation during topical aminolevulinic acid based photodynamic therapy (ALA-PDT) with a dark interval of 2 h leads to…”
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Laser speckle imaging of dynamic changes in flow during photodynamic therapy by Kruijt, B, de Bruijn, H S, van der Ploeg-van den Heuvel, A, Sterenborg, H J C M, Robinson, D J

“…We present a study investigating the use of laser speckle imaging (LSI) for monitoring blood flow during photodynamic therapy (PDT) utilizing the therapeutic…”
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Topical 5-Aminolevulinic Acid-photodynamic Therapy of Hairless Mouse Skin Using Two-fold Illumination Schemes: PpIX Fluorescence Kinetics, Photobleaching and Biological Effect by Robinson, Dominic J., de Bruijn, Henriëtte S., Johannes de Wolf, W., Sterenborg, Henricus J. C M., Star, Willem M.

“…Light fractionation with dark periods of the order of hours has been shown to considerably increase the efficacy of 5-aminolevulinic acid-photodynamic therapy…”
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Protoporphyrin IX Fluorescence Photobleaching during ALA-Mediated Photodynamic Therapy of UVB-Induced Tumors in Hairless Mouse Skin by Robinson, Dominic J., de Bruijn, Henriëtte S., van der Veen, Nynke, Stringer, Mark R., Brown, Stanley B., Star, Willem M.

“…— Fluorescence photobleaching of protoporphyrin IX (PpIX) during superficial photodynamic therapy (PDT), using 514 nm excitation, was studied in UVB‐induced…”
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Protoporphyrin IX Fluorescence Kinetics and Localization after Topical Application of ALA Pentyl Ester and ALA on Hairless Mouse Skin with UVB-Induced Early Skin Cancer by Akker, Johanna T. H Mvan den, Bruijn, Henriëtte Sde, Henegouwen, Gerard M. J Beijersbergen van, Star, Willem M., Sterenborg, Henricus J. C M.

“…In order to improve the efficacy of 5-aminolevulinic acid-based (ALA) photodynamic therapy (PDT), different ALA derivatives are presently being investigated…”
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Photobleaching during and re‐appearance after photodynamic therapy of topical ALA‐induced fluorescence in UVB‐treated mouse skin by Van Der Veen, Nynke, De Bruijn, Henriëtte S., Star, Willem M.

“…Photodynamic therapy (PDT) using protoporphyrin IX (PpIX) induced by topically applied 5‐aminolevulinic acid (ALA) seems a promising alternative for the…”
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Optimizing ALA-PDT in the management of non-melanoma skin cancer by fractionated illumination by De Vijlder, H C, Middelburg, T, De Bruijn, H S, Martino Neumann, H A, Sterenborg, H C J M, Robinson, D J, De Haas, E R M

“…The aim of this review was to describe briefly the mechanism and history of photodynamic therapy (PDT). The achieved preclinical and clinical results in…”
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Fluorescence Photobleaching of ALA-induced Protoporphyrin IX during Photodynamic Therapy of Normal Hairless Mouse Skin: The Effect of Light Dose and Irradiance and the Resulting Biological Effect by Robinson, Dominic J., de Bruijn, Henriëtte S., van der Veen, Nynke, Stringer, Mark R., Brown, Stanley B., Star, Willem M.

“…ABSTRACT The photobleaching of 5‐aminolaevulinic acid (ALA)‐induced protoporphyrin IX (PpIX) was investigated during superficial photodynamic therapy (PDT) in…”
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Monitoring in situ dosimetry and photoporphyrin IX fluorescence photobleaching in the normal rat esophagus during 5-aminolevulinic acid photodynamic therapy[para] by Boere, I A, Robinson, D J, de Bruijn, H S, van den Boogert, J

“…Experimental therapies for Barrett's esophagus, such as 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT), aim to ablate the premalignant Barrett's…”
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Fluorescence Photobleaching of ALA-induced Protoporphyrin IX during Photodynamic Therapy of Normal Hairless Mouse Skin: The Effect of Light Dose and Irradiance and the Resulting Biological Effect by Robinson, Dominic J., de Bruijn, Henriëtte S., van der Veen, Nynke, Stringer, Mark R., Brown, Stanley B., Star, Willem M.

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