Search Results - "de Bourcy, Charles F A"
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A quantitative comparison of single-cell whole genome amplification methods
Published in PloS one (19-08-2014)“…Single-cell sequencing is emerging as an important tool for studies of genomic heterogeneity. Whole genome amplification (WGA) is a key step in single-cell…”
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IDseq—An open source cloud-based pipeline and analysis service for metagenomic pathogen detection and monitoring
Published in Gigascience (15-10-2020)“…Abstract Background Metagenomic next-generation sequencing (mNGS) has enabled the rapid, unbiased detection and identification of microbes without…”
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c-Jun overexpression in CAR T cells induces exhaustion resistance
Published in Nature (London) (01-12-2019)“…Chimeric antigen receptor (CAR) T cells mediate anti-tumour effects in a small subset of patients with cancer 1 – 3 , but dysfunction due to T cell exhaustion…”
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Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2017)“…The elderly have reduced humoral immunity, as manifested by increased susceptibility to infections and impaired vaccine responses. To investigate the effects…”
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Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis
Published in Science immunology (29-09-2017)“…Systemic sclerosis with pulmonary arterial hypertension (SSc-PAH) is a debilitating and frequently lethal disease of unknown cause lacking effective treatment…”
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