Search Results - "de Boer, Onno"

Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease by Cortjens, Bart, de Boer, Onno J, de Jong, Rineke, Antonis, Adriaan FG, Sabogal Piñeros, Yanaika S, Lutter, René, van Woensel, Job BM, Bem, Reinout A

“…Human respiratory syncytial virus (RSV) is the most important cause of severe lower respiratory tract disease (LRTD) in young children worldwide. Extensive…”
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Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis by Res, Pieter C M, Piskin, Gamze, de Boer, Onno J, van der Loos, Chris M, Teeling, Peter, Bos, Jan D, Teunissen, Marcel B M

“…Although recent studies indicate a crucial role for IL-17A and IL-22 producing T cells in the pathogenesis of psoriasis, limited information is available on…”
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Extracellular traps derived from macrophages, mast cells, eosinophils and neutrophils are generated in a time‐dependent manner during atherothrombosis by Pertiwi, Kartika R, de Boer, Onno J, Mackaaij, Claire, Pabittei, Dara R, de Winter, Robbert J, Li, Xiaofei, van der Wal, Allard C

“…Extracellular traps generated by neutrophils contribute to thrombus progression in coronary atherosclerotic plaques. It is not known whether other inflammatory…”
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Role of Peptidylarginine Deiminase 4 in Neutrophil Extracellular Trap Formation and Host Defense during Klebsiella pneumoniae- Induced Pneumonia-Derived Sepsis by Claushuis, Theodora A M, van der Donk, Lieve E H, Luitse, Anna L, van Veen, Henk A, van der Wel, Nicole N, van Vught, Lonneke A, Roelofs, Joris J T H, de Boer, Onno J, Lankelma, Jacqueline M, Boon, Louis, de Vos, Alex F, van 't Veer, Cornelis, van der Poll, Tom

“…Peptidylarginine deiminase 4 (PAD4) catalyzes citrullination of histones, an important step for neutrophil extracellular trap (NET) formation. We aimed to…”
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Neutrophils, neutrophil extracellular traps and interleukin-17 associate with the organisation of thrombi in acute myocardial infarction by de Boer, Onno J, Li, Xiaofei, Teeling, Peter, Mackaay, Claire, Ploegmakers, Hanneke J, van der Loos, Chris M, Daemen, Mat J, de Winter, Robbert J, van der Wal, Allard C

“…Neutrophils are important cellular sources of interleukin (IL) 17A and -F. Moreover, upon activation neutrophils are able to excrete chromatin embedded with…”
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Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies by Lucas, Marit, Jansen, Ilaria, Savci-Heijink, C. Dilara, Meijer, Sybren L., de Boer, Onno J., van Leeuwen, Ton G., de Bruin, Daniel M., Marquering, Henk A.

“…Histopathologic grading of prostate cancer using Gleason patterns (GPs) is subject to a large inter-observer variability, which may result in suboptimal…”
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Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions by De Sousa E Melo, Felipe, Wang, Xin, Jansen, Marnix, Fessler, Evelyn, Trinh, Anne, de Rooij, Laura P M H, de Jong, Joan H, de Boer, Onno J, van Leersum, Ronald, Bijlsma, Maarten F, Rodermond, Hans, van der Heijden, Maartje, van Noesel, Carel J M, Tuynman, Jurriaan B, Dekker, Evelien, Markowetz, Florian, Medema, Jan Paul, Vermeulen, Louis

“…Analysis of gene-expression profiles led to the identification of three molecularly distinct subtypes of colon cancer. One of these subtypes is new, and its…”
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Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions by de Boer, Onno J, van der Meer, Jelger J, Teeling, Peter, van der Loos, Chris M, van der Wal, Allard C

“…T cell mediated inflammation contributes to atherogenesis and the onset of acute cardiovascular disease. Effector T cell functions are under a tight control of…”
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Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation by Stroo, Ingrid, Zeerleder, Sacha, Ding, Chao, Luken, Brenda M, Roelofs, Joris J T H, de Boer, Onno J, Meijers, Joost C M, Castellino, Francis J, van 't Veer, Cornelis, van der Poll, Tom

“…Bacterial pneumonia, the most common cause of sepsis, is associated with activation of coagulation. Factor XI (FXI), the key component of the intrinsic…”
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The role of Mannose Binding Lectin in the immune response against Borrelia burgdorferi sensu lato by Coumou, Jeroen, Wagemakers, Alex, Narasimhan, Sukanya, Schuijt, Tim J., Ersoz, Jasmin I., Oei, Anneke, de Boer, Onno J., Roelofs, Joris J. T. H., Fikrig, Erol, Hovius, Joppe W.

“…The causative agents of Lyme borreliosis, spirochetes belonging to the Borrelia burgdorferi sensu lato group, have developed several ways to protect themselves…”
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Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia by de Porto, Alexander P, Liu, Zhe, de Beer, Regina, Florquin, Sandrine, de Boer, Onno J, Hendriks, Rudi W, van der Poll, Tom, de Vos, Alex F

“…Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia…”
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Deep Learning for Histopathological Assessment of Esophageal Adenocarcinoma Precursor Lesions by Botros, Michel, de Boer, Onno J., Cardenas, Bryan, Bekkers, Erik J., Jansen, Marnix, van der Wel, Myrtle J., Sánchez, Clara I., Meijer, Sybren L.

“…Histopathological assessment of esophageal biopsies is a key part in the management of patients with Barrett esophagus (BE) but prone to observer variability…”
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The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice by de Vos, Alex F, Dessing, Mark C, Lammers, Adriana J J, de Porto, Alexander P N A, Florquin, Sandrine, de Boer, Onno J, de Beer, Regina, Terpstra, Sanne, Bootsma, Hester J, Hermans, Peter W, van 't Veer, Cornelis, van der Poll, Tom

“…Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus…”
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Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques by de Boer, Onno J, van der Meer, Jelger J, Teeling, Peter, van der Loos, Chris M, Idu, Mirza M, van Maldegem, Febe, Aten, Jan, van der Wal, Allard C

“…In addition to the classical TH1 and TH2 cytokines, members of the recently identified IL-17 cytokine family play an important role in regulating cellular and…”
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Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain by Uil, Melissa, Scantlebery, Angelique M. L., Butter, Loes M., Larsen, Per W. B., de Boer, Onno J., Leemans, Jaklien C., Florquin, Sandrine, Roelofs, Joris J. T. H.

“…Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models are essential tools for designing new strategies to prevent DN. C57Bl/6…”
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Atherosclerosis in the circle of Willis: Spatial differences in composition and in distribution of plaques by Denswil, Nerissa P, van der Wal, Allard C, Ritz, Katja, de Boer, Onno J, Aronica, Eleonora, Troost, Dirk, Daemen, Mat J.A.P

“…Abstract Background and aims Intracranial atherosclerosis is one of the main causes of ischemic stroke. However, the characteristics of intracranial arteries…”
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Enrichment of type 1 innate lymphoid cells in the course of human atherosclerotic plaque development suggests contribution to atherogenesis by Pertiwi, Kartika R, Teunissen, Marcel B M, Krebbers, Gabrielle, Willems, Martine C M, Huisman, Laurens, Poelen, Cindy, van der Wal, Allard C, de Boer, Onno J

“…Innate lymphoid cells (ILCs) have been implicated in multiple pathologic conditions, including atherogenesis, as documented in experimental mice studies,…”
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Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain by Uil, Melissa, Scantlebery, Angelique M. L., Butter, Loes M., Larsen, Per W. B., de Boer, Onno J., Leemans, Jaklien C., Florquin, Sandrine, Roelofs, Joris J. T. H.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice by Lieshout, Miriam H.P., Vos, Alex F., Dessing, Mark C., Porto, Alexander P.N.A., Boer, Onno J., Beer, Regina, Terpstra, Sanne, Florquin, Sandrine, van't Veer, Cornelis, der Poll, Tom

“…Streptococcus (S.) pneumoniae is the most common cause of community‐acquired pneumonia. The Nod‐like receptor family pyrin domain containing 3 (NLRP3)…”
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Microvascular proliferation in arteriovenous malformation of the hand worsens during pregnancy: a case report by Utami, Amalia M, Horbach, Sophie E R, Meijer-Jorna, Lorine B, Waas, Ingeborg S E, de Boer, Onno J, van der Wal, Allard C, van der Horst, Chantal M A M

“…Arteriovenous malformations (AVMs) are rare congenital disorders characterized by episodes of disproportionate growth that can cause pain and severe bleeding,…”
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