Search Results - "de Boer, Herman A."

Characterization of Recombinant Human Lactoferrin Secreted in Milk of Transgenic Mice by Nuijens, Jan H., van Berkel, Patrick H.C., Geerts, Marlieke E.J., Hartevelt, Peter Paul, de Boer, Herman A., van Veen, Harry A., Pieper, Frank R.

“…Human lactoferrin (hLF) is an iron-binding protein involved in host defense against infection and severe inflammation. Transgenic mice were produced harboring…”
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DNA determinants of rRNA synthesis in E. coli: growth rate dependent regulation, feedback inhibition, upstream activation, antitermination by Gourse, R L, de Boer, H A, Nomura, M

“…We have examined the DNA regions required for rRNA synthesis in E. coli using promoter-lacZ and lambda PL-rrnB operon fusions. Sequences between -51 and -20…”
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Expression of a functional mouse-human chimeric anti-CD19 antibody in the milk of transgenic mice by VAN KUIK-ROMEIJN, P, DE GROOT, N, HOOIJBERG, E, DE BOER, H. A

“…Human B cell lymphomas are suitable targets for immunotherapy. Clinical trials with mouse-human chimeric B cell-specific monoclonal antibodies (mAbs) have…”
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Expression of human lactoferrin in milk of transgenic mice by PLATENBURG, G. J, KOOTWIJK, E. P. A, KOOIMAN, P. M, WOLOSHUK, S. L, NUIJENS, J. H, KRIMPENFORT, P. J. A, PIEPER, F. R, DE BOER, H. A, STRIJKER, R

“…The expression of human lactoferrin (hLF) in the milk of transgenic mice is described. Regulatory sequences derived from the bovine alpha S1-casein gene were…”
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Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by DE GROOT, N, VAN KUIK-ROMEIJN, P, SANG HA LEE, DE BOER, H. A

“…The polymeric immunoglobulin receptor (pIgR), a transmembrane protein, transports dimeric IgA (dIgA) across the epithelial cells of the mucosal surfaces into…”
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Sequences within ribosome binding site affecting messenger RNA translatability and method to direct ribosomes to single messenger RNA species by de Boer, H A, Hui, A S

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Specific inhibition of ribosomal RNA synthesis in vitro by guanosine 3′ diphosphate, 5′ diphosphate by VAN OOYEN, ALBERT J. J, DE BOER, HERMAN A, AB, GEERT, GRUBER, MAX

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Recombinant Human Acid α-Glucosidase: High Level Production in Mouse Milk, Biochemical Characteristics, Correction of Enzyme Deficiency in GSDII KO Mice by Bijvoet, Agnes G. A., Kroos, Marian A., Pieper, Frank R., Van der Vliet, Martin, De Boer, Herman A., Van der Ploeg, Ans T., Verbeet, Martin Ph, Reuser, Arnold J. J.

“…Glycogen storage disease type II (GSDII) is caused by lysosomal acid α-glucosidase deficiency. Patients have a rapidly fatal or slowly progressive impairment…”
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N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA by van Berkel, P H, Geerts, M E, van Veen, H A, Mericskay, M, de Boer, H A, Nuijens, J H

“…Human lactoferrin (hLF), a protein involved in host defence against infection and excessive inflammation, interacts with heparin, the lipid A moiety of…”
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Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs by HAMILTON, R, WATANABE, C. K, DE BOER, H. A

“…The nucleotide sequence of the translation initiation regions of 96 Saccharomyces cerevisiae mRNAs was compiled and compared. The entire 5' untranslated…”
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Specialized Ribosome System: Preferential Translation of a Single mRNA Species by a Subpopulation of Mutated Ribosomes in Escherichia coli by Hui, Anna, De Boer, Herman A.

“…In Escherichia coli, all mRNAs are translated by one pool of functionally identical ribosomes. Here, we describe a system in which a subpopulation of modified…”
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Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation by Brink, Marcel F., Brink, Guido, Verbeet, Martin, de Boer, Herman A.

“…The upper stem of helix 34, consisting of the basepaired sequences C1063G1064U1065 and A1191C1192G1193, is suggested to be involved in the binding of…”
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The tac Promoter: A Functional Hybrid Derived from the trp and lac Promoters by De Boer, Herman A., Comstock, Lisa J., Vasser, Mark

“…Two hybrid promoters that are functional in Escherichia coli have been constructed. These hybrid promoters, tacI and tacII, were derived from sequences of the…”
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Corrigendum - Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by de Groot, Nanda, van Kuik-Romeijn, Petra, Lee, Sang He, de Boer, Herman A

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Cloning and characterization of the bovine polymeric immunoglobulin receptor-encoding cDNA by Verbeet, Martin Ph, Vermeer, Hendrika, Warmerdam, Gertrüd C.M., de Boer, Herman A., Lee, Sang He

“…Trans-epithelial transport of polymeric immunoglobulins (pIg) into mucosal and glandular secretions is carried out by the pIg receptor (pIgR). Therefore,…”
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Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice by Groot, Nanda De, Kuik-romeijn, Petra Van, Lee, Sang He, de Boer, Herman A

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Specialized ribosomes: highly specific translation in vivo of a single targetted mRNA species by Brink, Marcel F., Verbeet, Martin Ph, de Boer, Herman A.

“…In previous studies [Hui and de Boer, Proc. Natl. Acad. Sci. USA 84 (1987) 4762–4766; Hui et al., Methods Enzymol. 153 (1987) 432–452], it was shown that…”
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Spectinomycin interacts specifically with the residues G 1064 and C 1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation by Brink, Marcel F., Brink, Guido, Verbeet, Martin, de Boer, Herman A.

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High-level expression of bovine [alpha]s1-casein in milk of transgenic mice by Rijnkels, Monique, Kooiman, Patricia M, Platenburg, Gerard J, van Dixhoorn, Mieneke, Nuijens, Jan H, de Boer, Herman A, Pieper, Frank R

“…The bovine αs1-casein gene, isolated from a cosmid library, was introduced into the murine germline. Transgene expression occurred in all transgenic mice, and…”
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Mammary gland-specific hypomethylation ofHpa II sites flanking the bovine αS1-casein gene by Platenburg, Gerard J., Vollebregt, Ellen J., Karatzas, Costas N., Kootwijk, Erika P. A., De Boer, Herman A., Strijker, Rein

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