Search Results - "de Boer, Casper"

Thinking-While-Moving Exercises May Improve Cognition in Elderly with Mild Cognitive Deficits: A Proof-of-Principle Study by de Boer, Casper, Echlin, Holly V., Rogojin, Alica, Baltaretu, Bianca R., Sergio, Lauren E.

“…Background: Noninvasive interventions to aid healthy cognitive aging are considered an important healthcare priority. Traditional approaches typically focus on…”
Get full text

Mini-Mental State Examination subscores indicate visuomotor deficits in Alzheimer's disease patients: A cross-sectional study in a Dutch population by de Boer, Casper, Mattace-Raso, Francesco, van der Steen, Johannes, Pel, Johan JM

“…Aim In diagnostics of Alzheimer's disease (AD), the Mini‐Mental State Examination (MMSE) questionnaire is frequently used to test cognitive decline. The final…”
Get full text

An overview of activity-based probes for glycosidases by Wu, Liang, Armstrong, Zachary, Schröder, Sybrin P, de Boer, Casper, Artola, Marta, Aerts, Johannes MFG, Overkleeft, Herman S, Davies, Gideon J

“…•Glycosidases carry out many essential functions across all domains of life.•Activity-based probes can interrogate complex biological samples for glycosidase…”
Get full text

Prediction of Alzheimer's disease biomarker status defined by the 'ATN framework' among cognitively healthy individuals: results from the EPAD longitudinal cohort study by Calvin, Catherine M, de Boer, Casper, Raymont, Vanessa, Gallacher, John, Koychev, Ivan

“…The Amyloid/Tau/Neurodegeneration (ATN) framework has been proposed as a means of evidencing the biological state of Alzheimer's disease (AD). Predicting ATN…”
Get full text

On the Origin of Regioselectivity in Palladium‐Catalyzed Oxidation of Glucosides by Wan, Ieng Chim (Steven), Hamlin, Trevor A., Eisink, Niek N. H. M., Marinus, Nittert, Boer, Casper, Vis, Christopher A., Codée, Jeroen D. C., Witte, Martin D., Minnaard, Adriaan J., Bickelhaupt, F. Matthias

“…The palladium‐catalyzed oxidation of glucopyranosides has been investigated using relativistic density functional theory (DFT) at ZORA‐BLYP−D3(BJ)/TZ2P. The…”
Get full text

Ethical challenges of using remote monitoring technologies for clinical research: A case study of the role of local research ethics committees in the RADAR-AD study by Muurling, Marijn, Pasmooij, Anna M G, Koychev, Ivan, Roik, Dora, Froelich, Lutz, Schwertner, Emilia, Religa, Dorota, Abdelnour, Carla, Boada, Mercè, Almici, Monica, Galluzzi, Samantha, Cardoso, Sandra, de Mendonça, Alexandre, Owens, Andrew P, Kuruppu, Sajini, Gjestsen, Martha Therese, Lazarou, Ioulietta, Gkioka, Mara, Tsolaki, Magda, Diaz, Ana, Gove, Dianne, Visser, Pieter Jelle, Aarsland, Dag, Lucivero, Federica, de Boer, Casper

“…Clinical research with remote monitoring technologies (RMTs) has multiple advantages over standard paper-pencil tests, but also raises several ethical…”
Get full text

Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study by Muurling, Marijn, de Boer, Casper, Kozak, Rouba, Religa, Dorota, Koychev, Ivan, Verheij, Herman, Nies, Vera J M, Duyndam, Alexander, Sood, Meemansa, Fröhlich, Holger, Hannesdottir, Kristin, Erdemli, Gul, Lucivero, Federica, Lancaster, Claire, Hinds, Chris, Stravopoulos, Thanos G, Nikolopoulos, Spiros, Kompatsiaris, Ioannis, Manyakov, Nikolay V, Owens, Andrew P, Narayan, Vaibhav A, Aarsland, Dag, Visser, Pieter Jelle

“…Functional decline in Alzheimer's disease (AD) is typically measured using single-time point subjective rating scales, which rely on direct observation or…”
Get full text

Physical activity levels in cognitively normal and cognitively impaired oldest-old and the association with dementia risk factors: a pilot study by Muurling, Marijn, Badissi, Maryam, de Boer, Casper, Legdeur, Nienke, Barkhof, Frederik, van Berckel, Bart N M, Maier, Andrea B, Pijnappels, Mirjam, Visser, Pieter Jelle

“…Research assessing the relationship of physical activity and dementia is usually based on studies with individuals younger than 90 years of age. The primary…”
Get full text

Digital endpoints in clinical trials of Alzheimer's disease and other neurodegenerative diseases: challenges and opportunities by Brem, Anna-Katharine, Kuruppu, Sajini, de Boer, Casper, Muurling, Marijn, Diaz-Ponce, Ana, Gove, Dianne, Curcic, Jelena, Pilotto, Andrea, Ng, Wan-Fai, Cummins, Nicholas, Malzbender, Kristina, Nies, Vera J M, Erdemli, Gul, Graeber, Johanna, Narayan, Vaibhav A, Rochester, Lynn, Maetzler, Walter, Aarsland, Dag

“…Alzheimer's disease (AD) and other neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's disease (HD) are associated with progressive…”
Get full text

Digital remote assessment of speech acoustics in cognitively unimpaired adults: feasibility, reliability and associations with amyloid pathology by van den Berg, Rosanne L, de Boer, Casper, Zwan, Marissa D, Jutten, Roos J, van Liere, Mariska, van de Glind, Marie-Christine A B J, Dubbelman, Mark A, Schlüter, Lisa Marie, van Harten, Argonde C, Teunissen, Charlotte E, van de Giessen, Elsmarieke, Barkhof, Frederik, Collij, Lyduine E, Robin, Jessica, Simpson, William, Harrison, John E, van der Flier, Wiesje M, Sikkes, Sietske A M

“…Digital speech assessment has potential relevance in the earliest, preclinical stages of Alzheimer's disease (AD). We evaluated the feasibility, test-retest…”
Get full text

Regulatory considerations for developing remote measurement technologies for Alzheimer’s disease research by Erdemli, Gül, Grammatikopoulou, Margarita, Wagner, Bertil, Vairavan, Srinivasan, Curcic, Jelena, Aarsland, Dag, Wittenberg, Gayle, Nikolopoulos, Spiros, Muurling, Marijn, Froehlich, Holger, de Boer, Casper, Shanbhag, Niraj M., Nies, Vera J. M., Coello, Neva, Gove, Dianne, Diaz, Ana, Foy, Suzanne, Dartee, Wim, Brem, Anna-Katharine

“…The Remote Assessment of Disease and Relapse – Alzheimer’s Disease (RADAR-AD) consortium evaluated remote measurement technologies (RMTs) for assessing…”
Get full text

The reporting of neuropsychiatric symptoms in electronic health records of individuals with Alzheimer's disease: a natural language processing study by Eikelboom, Willem S, Singleton, Ellen H, van den Berg, Esther, de Boer, Casper, Coesmans, Michiel, Goudzwaard, Jeannette A, Vijverberg, Everard G B, Pan, Michel, Gouw, Cornalijn, Mol, Merel O, Gillissen, Freek, Fieldhouse, Jay L P, Pijnenburg, Yolande A L, van der Flier, Wiesje M, van Swieten, John C, Ossenkoppele, Rik, Kors, Jan A, Papma, Janne M

“…Neuropsychiatric symptoms (NPS) are prevalent in the early clinical stages of Alzheimer's disease (AD) according to proxy-based instruments. Little is known…”
Get full text

A Multiplexing Activity-Based Protein-Profiling Platform for Dissection of a Native Bacterial Xyloglucan-Degrading System by McGregor, Nicholas G. S., de Boer, Casper, Foucart, Quentin P. O., Beenakker, Thomas, Offen, Wendy A., Codée, Jeroen D. C., Willems, Lianne I., Overkleeft, Herman S., Davies, Gideon J.

“…Bacteria and yeasts grow on biomass polysaccharides by expressing and excreting a complex array of glycoside hydrolase (GH) enzymes. Identification and…”
Get full text

Early Trajectory Prediction in Elite Athletes by Owens, Cullen B., de Boer, Casper, Gennari, Giulia, Broersen, Robin, Pel, Johan J., Miller, Brian, Clapp, Wesley, van der Werf, Ysbrand D., De Zeeuw, Chris I.

“…Cerebellar plasticity is a critical mechanism for optimal feedback control. While Purkinje cell activity of the oculomotor vermis predicts eye movement speed…”
Get full text

Augmented reality versus standard tests to assess cognition and function in early Alzheimer’s disease by Muurling, Marijn, de Boer, Casper, Vairavan, Srinivasan, Harms, Robbert L., Chadha, Antonella Santuccione, Tarnanas, Ioannis, Luis, Estefania Vilarino, Religa, Dorota, Gjestsen, Martha Therese, Galluzzi, Samantha, Ibarria Sala, Marta, Koychev, Ivan, Hausner, Lucrezia, Gkioka, Mara, Aarsland, Dag, Visser, Pieter Jelle, Brem, Anna-Katharine

“…Augmented reality (AR) apps, in which the virtual and real world are combined, can recreate instrumental activities of daily living (IADL) and are therefore…”
Get full text

Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes by Schröder, Sybrin P, de Boer, Casper, McGregor, Nicholas G. S, Rowland, Rhianna J, Moroz, Olga, Blagova, Elena, Reijngoud, Jos, Arentshorst, Mark, Osborn, David, Morant, Marc D, Abbate, Eric, Stringer, Mary A, Krogh, Kristian B. R. M, Raich, Lluís, Rovira, Carme, Berrin, Jean-Guy, van Wezel, Gilles P, Ram, Arthur F. J, Florea, Bogdan I, van der Marel, Gijsbert A, Codée, Jeroen D. C, Wilson, Keith S, Wu, Liang, Davies, Gideon J, Overkleeft, Herman S

“…Plant polysaccharides represent a virtually unlimited feedstock for the generation of biofuels and other commodities. However, the extraordinary recalcitrance…”
Get full text

Assessment of Social Behavior Using a Passive Monitoring App in Cognitively Normal and Cognitively Impaired Older Adults: Observational Study by Muurling, Marijn, Reus, Lianne M, de Boer, Casper, Wessels, Sterre C, Jagesar, Raj R, Vorstman, Jacob A S, Kas, Martien J H, Visser, Pieter Jelle

“…In people with cognitive impairment, loss of social interactions has a major impact on well-being. Therefore, patients would benefit from early detection of…”
Get full text

Feasibility and usability of remote monitoring in Alzheimer's disease by Muurling, Marijn, de Boer, Casper, Hinds, Chris, Atreya, Alankar, Doherty, Aiden, Alepopoulos, Vasilis, Curcic, Jelena, Brem, Anna-Katharine, Conde, Pauline, Kuruppu, Sajini, Morató, Xavier, Saletti, Valentina, Galluzzi, Samantha, Vilarino Luis, Estefania, Cardoso, Sandra, Stukelj, Tina, Kramberger, Milica Gregorič, Roik, Dora, Koychev, Ivan, Hopøy, Ann-Cecilie, Schwertner, Emilia, Gkioka, Mara, Aarsland, Dag, Visser, Pieter Jelle

“…Remote monitoring technologies (RMTs) can measure cognitive and functional decline objectively at-home, and offer opportunities to measure passively and…”
Get full text

Continuous and risk‐score‐based predictors of ATN Alzheimer's disease status among cognitively healthy individuals: Findings from the EPAD‐LCS study: Neuroimaging / Optimal neuroimaging measures for early detection by Calvin, Catherine M, de Boer, Casper, Raymont, Vanessa, Gallacher, John, Koychev, Ivan G

“…Abstract Background The Amyloid/Tau/Neurodegeneration (ATN) framework has been proposed as means of evidencing the biological state of Alzheimer’s disease…”
Get full text

Continuous and risk‐score‐based predictors of ATN Alzheimer's disease status among cognitively healthy individuals: Findings from the EPAD‐LCS study by Calvin, Catherine M, de Boer, Casper, Raymont, Vanessa, Gallacher, John, Koychev, Ivan G

“…Background The Amyloid/Tau/Neurodegeneration (ATN) framework has been proposed as means of evidencing the biological state of Alzheimer’s disease (AD)…”
Get full text