Search Results - "de Baaij, Jeroen H.F"

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  1. 1

    Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation? by ter Braake, Anique D, Shanahan, Catherine M, de Baaij, Jeroen H.F

    “…Over the last decade, an increasing number of studies report a close relationship between serum magnesium concentration and cardiovascular disease risk in the…”
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    Hypomagnesemia and Cardiovascular Risk in Type 2 Diabetes by Oost, Lynette J, Tack, Cees J, de Baaij, Jeroen H F

    Published in Endocrine reviews (01-06-2023)
    “…Abstract Hypomagnesemia is 10-fold more common in individuals with type 2 diabetes (T2D) than in the healthy population. Factors that are involved in this high…”
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    Mitochondrial Dysfunction in Kidney Tubulopathies by Hoogstraten, Charlotte A, Hoenderop, Joost G, de Baaij, Jeroen H.F

    Published in Annual review of physiology (12-02-2024)
    “…Mitochondria play a key role in kidney physiology and pathology. They produce ATP to fuel energy-demanding water and solute reabsorption processes along the…”
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    Magnesium and calciprotein particles in vascular calcification: the good cop and the bad cop by Zeper, Lara W, de Baaij, Jeroen H.F

    “…PURPOSE OF REVIEWVascular calcification is a major contributor to increased cardiovascular mortality in chronic kidney disease (CKD). Recently, calciprotein…”
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    CNNM2 mutations cause impaired brain development and seizures in patients with hypomagnesemia by Arjona, Francisco J, de Baaij, Jeroen H F, Schlingmann, Karl P, Lameris, Anke L L, van Wijk, Erwin, Flik, Gert, Regele, Sabrina, Korenke, G Christoph, Neophytou, Birgit, Rust, Stephan, Reintjes, Nadine, Konrad, Martin, Bindels, René J M, Hoenderop, Joost G J

    Published in PLoS genetics (01-04-2014)
    “…Intellectual disability and seizures are frequently associated with hypomagnesemia and have an important genetic component. However, to find the genetic origin…”
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    Genetics of renovascular hypertension in children by Viering, Daan H.H.M., Chan, Melanie M.Y., Hoogenboom, Lieke, Iancu, Daniela, de Baaij, Jeroen H.F., Tullus, Kjell, Kleta, Robert, Bockenhauer, Detlef

    Published in Journal of hypertension (01-10-2020)
    “…OBJECTIVE:In most cases of renovascular hypertension in children, the cause is unclear. The aim of this study was to investigate genetic variation as a factor…”
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    Membrane Topology and Intracellular Processing of Cyclin M2 (CNNM2) by de Baaij, Jeroen H.F., Stuiver, Marchel, Meij, Iwan C., Lainez, Sergio, Kopplin, Kathrin, Venselaar, Hanka, Müller, Dominik, Bindels, René J.M., Hoenderop, Joost G.J.

    Published in The Journal of biological chemistry (20-04-2012)
    “…Recently, mutations in the cyclin M2 (CNNM2) gene were identified to be causative for severe hypomagnesemia. In kidney, CNNM2 is a basolaterally expressed…”
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    Identification of SLC41A3 as a novel player in magnesium homeostasis by de Baaij, Jeroen H.F., Arjona, Francisco J., van den Brand, Michiel, Lavrijsen, Marla, Lameris, Anke L.L., Bindels, René J.M., Hoenderop, Joost G.J.

    Published in Scientific reports (28-06-2016)
    “…Regulation of the body Mg 2+ balance takes place in the distal convoluted tubule (DCT), where transcellular reabsorption determines the final urinary Mg 2+…”
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    Metformin regulates TRPM6, a potential explanation for magnesium imbalance in type 2 diabetes patients by Bouras, Hacene, Roig, Sara R, Kurstjens, Steef, Tack, Cees J J, Kebieche, Mohamed, de Baaij, Jeroen H F, Hoenderop, Joost G J

    “…Metformin therapy is associated with lower serum magnesium (Mg ) levels in type 2 diabetes patients. The TRPM6 channel determines the fine-tuning of Mg…”
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    Development of a villi-like micropatterned porous membrane for intestinal magnesium and calcium uptake studies by Gommers, Lisanne M.M., Skrzypek, Katarzyna, Bolhuis-Versteeg, Lydia, Pinckaers, Nicole E.T., Vrijhof, Rob, van der Wijst, Jenny, de Baaij, Jeroen H.F., Stamatialis, Dimitrios, Hoenderop, Joost G.J.

    Published in Acta biomaterialia (01-11-2019)
    “…[Display omitted] Intestinal enterocytes are key players in the absorption of magnesium (Mg2+) and calcium (Ca2+). Understanding the exact molecular mechanisms…”
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    Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice by Kurstjens, Steef, Bouras, Hacene, Overmars-Bos, Caro, Kebieche, Mohamed, Bindels, René J. M., Hoenderop, Joost G. J., de Baaij, Jeroen H. F.

    Published in Scientific reports (11-02-2019)
    “…Approximately 30% of patients with type 2 diabetes mellitus (T2D) have hypomagnesemia (blood magnesium (Mg 2+ ) concentration <0.7 mmol/L). In T2D patients,…”
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    A de novo KCNA1 Mutation in a Patient with Tetany and Hypomagnesemia by van der Wijst, Jenny, Konrad, Martin, Verkaart, Sjoerd A J, Tkaczyk, Marcin, Latta, Femke, Altmüller, Janine, Thiele, Holger, Beck, Bodo, Schlingmann, Karl Peter, de Baaij, Jeroen H F

    Published in Nephron (2015) (01-01-2018)
    “…Mutations in the KCNA1 gene encoding the voltage-gated potassium (K+) channel Kv1.1 have been linked to rare neurological syndromes, episodic ataxia type 1…”
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    Effect of Dapagliflozin Treatment on the Expression of Renal Sodium Transporters/Channels on High-Fat Diet Diabetic Mice by Ma, Chao, de Baaij, Jeroen H F, Millar, Paul J, Gault, Victor A, de Galan, Bastiaan E, Bindels, René J M, Hoenderop, Joost G J

    Published in Nephron (2015) (01-01-2019)
    “…Inhibition of the Na+/glucose co-transporter 2 is a new therapeutic strategy for diabetes. It is unclear how proximal loss of Na+ (and glucose) affects the…”
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    Regulation of Mg2+ Reabsorption and Transient Receptor Potential Melastatin Type 6 Activity by cAMP Signaling by Blanchard, Maxime G, Kittikulsuth, Wararat, Nair, Anil V, de Baaij, Jeroen H F, Latta, Femke, Genzen, Jonathan R, Kohan, Donald E, Bindels, René J M, Hoenderop, Joost G J

    “…The transient receptor potential melastatin type 6 (TRPM6) epithelial Mg(2+) channels participate in transcellular Mg(2+) transport in the kidney and…”
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    Hypomagnesemia as First Clinical Manifestation of ADTKD-HNF1B: A Case Series and Literature Review by van der Made, Cas I, Hoorn, Ewout J, de la Faille, Renaud, Karaaslan, Huseyin, Knoers, Nine V A M, Hoenderop, Joost G J, Vargas Poussou, Rosa, de Baaij, Jeroen H F

    Published in American journal of nephrology (01-01-2015)
    “…Autosomal dominant tubulointerstitial kidney disease subtype HNF1B (ADTKD-HNF1B) is caused by a mutation in hepatocyte nuclear factor 1 homeobox beta (HNF1B)…”
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    Magnesium reabsorption in the kidney by de Baaij, Jeroen H F

    “…Mg is essential for many cellular and physiological processes, including muscle contraction, neuronal activity, and metabolism. Consequently, the blood Mg…”
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