Search Results - "de Azevedo Silva, Jaqueline"
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Differential expression of the inflammasome complex genes in systemic lupus erythematosus
Published in Immunogenetics (New York) (01-05-2020)“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder involving heterogeneous clinical manifestations and numerous susceptibility genes. Several…”
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2
Postmenopausal Osteoporosis reference genes for qPCR expression assays
Published in Scientific reports (11-11-2019)“…Osteoporosis (OP) is a multifactorial disease influenced by genetic factors in more than half of the cases. In spite of the efforts to clarify the relationship…”
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3
Expression profile of inflammasome genes in individuals with Down syndrome
Published in Genetics and molecular biology (01-01-2024)“…Down syndrome (DS), affecting 1 in 700 live births, is the most prevalent chromosomal disorder among newborns. Recognizable by classical clinical features,…”
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4
Vitamin D receptor gene polymorphisms influence on clinical profile and bone mineral density at different skeletal sites in postmenopausal osteoporotic women
Published in International journal of immunogenetics (01-04-2023)“…Bone remodeling is marked by bone synthesis and absorption balance, and any altered dynamic in this process leads to osteoporosis (OP). The interaction of…”
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Caveolin-1 (CAV-1) up regulation in metabolic syndrome: all roads leading to the same end
Published in Molecular biology reports (01-11-2020)“…Metabolic syndrome (MS) is a set of clinical conditions such as insulin resistance, hyperglycemia, systemic arterial hypertension (SAH), dyslipidemia, obesity…”
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Is there an Inflammation Role for MYD88 in Rheumatoid Arthritis?
Published in Inflammation (01-06-2021)“…Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease with strong genetic influence, especially upon immune response components. Several…”
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Ficolin Gene Polymorphisms in Systemic Lupus Erythematosus and Rheumatoid Arthritis
Published in Annals of human genetics (01-01-2016)“…Summary Systemic lupus erythemathosus (SLE) and rheumatoid arthritis (RA) are complex autoimmune diseases characterized by an immune balance breakdown and by…”
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VDR polymorphisms influence immunological response in HIV-1+ individuals undergoing antiretroviral therapy
Published in Genetics and molecular biology (01-04-2019)“…Vitamin D exerts an immuno-modulatory activity on several immune system cells through the vitamin D receptor (VDR). Herein, we verified that age and a…”
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Mechanism of inflammatory response in associated comorbidities in COVID-19
Published in Diabetes & metabolic syndrome clinical research & reviews (01-07-2020)“…The outbreak of the new coronavirus, SARS-CoV-2, causes a respiratory disease and individuals with pre-existing cardiometabolic disorders display worse…”
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10
LIG4 and RAD52 DNA repair genes polymorphisms and systemic lupus erythematosus
Published in Molecular biology reports (2014)“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder with a strong genetic background. Nevertheless, SLE might also be triggered due to…”
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11
Down regulation of VDR gene expression in metabolic syndrome and atherosclerosis’ patients: Cause or consequence?
Published in Gene (01-03-2021)“…•MS patients present lower mRNA levels of VDR compared to healthy individuals.•VDR is down regulated in atherosclerosis patients.•VDR is decreased in severe…”
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Inflammasome activation by NLRP1 and NLRC4 in patients with coronary stenosis
Published in Immunobiology (1979) (01-05-2020)“…•The inflammasome complex is activated in atherosclerosis also by interaction with NLRP1 and NLRC4 receptors.•IL-1β gene expression is an important marker in…”
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13
Pathogen recognition pathway gene variants and inflammasome sensors gene expression in tuberculosis patients under treatment
Published in Molecular biology reports (01-12-2024)“…Background Several epidemiological studies have suggested that genetic variations in encoding pattern recognition receptors (PRRs) genes such as Toll Like…”
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14
Investigating the influence of inflammasome complex genes on Turner syndrome
Published in Human immunology (01-11-2024)“…Turner syndrome (TS) is associated with an increased susceptibility to inflammatory and autoimmune diseases. This study investigates the association between…”
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15
Steroid immune responsive gene regulation in Mycobacterium tuberculosis infection in vitro
Published in Tuberculosis (Edinburgh, Scotland) (01-05-2024)“…Tuberculosis (TB) is an infectious disease displaying a multifactorial pathology. The immunomodulatory role attributed to steroid hormones, such as vitamin D3…”
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Are key cytokines genetic and serum levels variations related to rheumatoid arthritis clinical severity?
Published in Gene (05-01-2020)“…This study evaluated the possible association between SNPs in cytokines coding genes, namely IL10, IL6 and IFNG, cytokines serum levels and clinical…”
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DC-SIGN polymorphisms are associated to type 1 diabetes mellitus
Published in Immunobiology (1979) (01-11-2014)“…Abstract Type I diabetes mellitus (T1DM) is an autoimmune disorder featured by raised glucoses levels. It has been hypothesised that raised glucose levels in…”
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Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients
Published in Inflammation research (01-03-2018)“…Objective In the present study, we analyzed the possible association of inflammasome gene variants and expression to rheumatoid arthritis (RA)’s development…”
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Upregulation of FOXP3 may act on immunological misbalance in Turner syndrome
Published in Scandinavian journal of immunology (01-03-2023)“…Turner syndrome (TS) presents a characteristic immune imbalance among patients. As the X chromosome‐linked FOXP3 gene is a powerful immune regulator, in this…”
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PTPN22 1858C > T polymorphism and susceptibility to systemic lupus erythematosus: a meta-analysis update
Published in Autoimmunity (Chur, Switzerland) (03-10-2017)“…Studies performed in the past years showed PTNP22 1858 C > T (rs2476601) polymorphism as associated with systemic lupus erythematosus susceptibility, although…”
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