Search Results - "de Azevedo Calderon, Leonardo"
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Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms
Published in Amino acids (01-10-2021)“…The worrisome emergence of pathogens resistant to conventional drugs has stimulated the search for new classes of antimicrobial and antiparasitic agents from…”
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2
Antiprotozoal action of synthetic cinnamic acid analogs
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-11-2018)“…Leishmaniasis, Chagas disease, and malaria cause morbidity globally. The drugs currently used for treatment have limitations. Activity of cinnamic acid analogs…”
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3
A natural cell-penetrating nanopeptide combined with pentavalent antimonial as experimental therapy against cutaneous leishmaniasis
Published in Experimental parasitology (01-10-2020)“…The inadequacy of available treatments for leishmaniasis has presented up to 40% therapeutic failure. This fact suggests an urgency in the discovery of new…”
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In vitro and ex vivo antiplasmodial activity of 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) against circulating strains of Plasmodium spp. in the state of Rondônia, Brazil
Published in Brazilian Journal of Pharmaceutical Sciences (2023)“…Abstract Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study…”
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Antimicrobial peptides from Phyllomedusa frogs: from biomolecular diversity to potential nanotechnologic medical applications
Published in Amino acids (2011)“…Screening for new bioactive peptides in South American anurans has been pioneered in frogs of the genus Phyllomedusa. All frogs of this genus have venomous…”
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6
Amazonian biodiversity: a view of drug development for leishmaniasis and malaria
Published in Journal of the Brazilian Chemical Society (2009)Get full text
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7
Amazonian biodiversity: a view of drug development for Leishmaniasis and malaria
Published in Journal of the Brazilian Chemical Society (2009)“…Chemotherapy is the only validated therapy for the treatment for the neglected diseases leishmaniasis and malaria. However, the emergence of drug resistance,…”
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8
Partial purification of trypsin inhibitors from Parkia seeds (Fabaceae)
Published in Hoehnea (01-06-2014)“…Leguminous seeds (Fabaceae) have a high content of inhibitors of which serine protease inhibitors are the most widely studied. However, there are only a few…”
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9
Effect of Bothrops bilineata snake venom on neutrophil function
Published in Toxicon (Oxford) (15-12-2013)“…The aim of the study was to evaluate the in vitro effects of Bothrops bilineata crude venom (BbV) on isolated human neutrophil function. We proved that BbV…”
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10
New multienzymatic complex formed between human cathepsin D and snake venom phospholipase A2
Published in The journal of venomous animals and toxins including tropical diseases (2022)“…BackgroundCathepsin D (CatD) is a lysosomal proteolytic enzyme expressed in almost all tissues and organs. This protease is a multifunctional enzyme…”
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11
Cinnamic acid derived compounds loaded into liposomes: antileishmanial activity, production standardisation and characterisation
Published in Journal of microencapsulation (04-07-2015)“…Synthetic compounds derived from cinnamic acid were tested in cultures containing the promastigote form of Leishmania amazonensis and the dimethylsulphoxide…”
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12
Amphibia, Anura, Leptodactylidae, Leptodactylus chaquensis: distribution extension and geographic distribution map
Published in Check list (Luís Felipe Toledo) (01-08-2009)“…None…”
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13
Amphibia, Anura, Hylidae, Phyllomedusinae, Phyllomedusa azurea: distribution extension and geographic distribution map
Published in Check list (Luís Felipe Toledo) (01-06-2009)“…None…”
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14
Amazonian biodiversity: a view of drug development for leishmaniasis and malaria
Published in Journal of the Brazilian Chemical Society (2009)Get full text
Journal Article -
15
Partial purification of trypsin inhibitors from Parkia seeds (Fabaceae)
Published in Hoehnea“…Leguminous seeds (Fabaceae) have a high content of inhibitors of which serine protease inhibitors are the most widely studied. However, there are only a few…”
Get full text
Journal Article