Search Results - "de Araújo, João Xavier"

Efficient and Mild Ullmann‐Type N‐Arylation of Amides, Carbamates, and Azoles in Water by Bollenbach, Maud, Aquino, Pedro G. V., de Araújo‐Júnior, João Xavier, Bourguignon, Jean‐Jacques, Bihel, Frédéric, Salomé, Christophe, Wagner, Patrick, Schmitt, Martine

“…A simple, sustainable, efficient, mild, and low‐cost protocol was developed for d‐glucose‐assisted Cu‐catalyzed Ullmann reactions in water for amides,…”
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Computer-Aided Design, Synthesis, and Antiviral Evaluation of Novel Acrylamides as Potential Inhibitors of E3-E2-E1 Glycoproteins Complex from Chikungunya Virus by Passos, Gabriel Felipe Silva, Gomes, Matheus Gabriel Moura, Aquino, Thiago Mendonça de, Araújo-Júnior, João Xavier de, Souza, Stephannie Janaina Maia de, Cavalcante, João Pedro Monteiro, Santos, Elane Conceição Dos, Bassi, Ênio José, Silva-Júnior, Edeildo Ferreira da

“…Chikungunya virus (CHIKV) causes an infectious disease characterized by inflammation and pain of the musculoskeletal tissues accompanied by swelling in the…”
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Flavonoids from Praxelis clematidea R.M. King and Robinson modulate bacterial drug resistance by Maia, Gabriela Lemos de Azevedo, Falcão-Silva, Vivyanne dos Santos, Aquino, Pedro Gregório Vieira, de Araújo-Júnior, João Xavier, Tavares, Josean Fechine, da Silva, Marcelo Sobral, Rodrigues, Luis Cezar, de Siqueira-Júnior, José Pinto, Barbosa-Filho, José Maria

“…Chemical studies of Praxelis clematidea R.M. King & Robinson resulted in the isolation of six flavones: Apigenine, genkwanine, 7,4'-dimethylapigenin,…”
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Characterization and Stability of the Antimony-Quercetin Complex by Barbosa, Valcilaine Teixeira, de Menezes, Janaína Barros, Santos, Josué Carinhanha Caldas, Bastos, Maria Lysete de Assis, Araújo-Júnior, João Xavier de, Nascimento, Ticiano Gomes do, Basílio-Júnior, Irinaldo Diniz, Grillo, Luciano Aparecido Meireles, Dornelas, Camila Braga

“…Purpose: Quercetin is a flavonoid known for its therapeutic properties and for forming complexes. Although the antimony-quercetin (SbQ) complex has been…”
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Assessment of mechanisms involved in antinociception produced by the alkaloid caulerpine by Cavalcante-Silva, Luiz Henrique Agra, Falcão, Maria Alice Pimentel, Vieira, Ana Carolina Santana, Viana, Max Denisson Maurício, de Araújo-Júnior, João Xavier, Sousa, Jéssica Celestino Ferreira, da Silva, Tania Maria Sarmento, Barbosa-Filho, José Maria, Noël, François, de Miranda, George Emmanuel C, Santos, Bárbara Viviana de Oliveira, Alexandre-Moreira, Magna Suzana

“…In previous works we showed that oral administration of caulerpine, a bisindole alkaloid isolated from algae of the genus Caulerpa, produced antinociception…”
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Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses by Dos Santos Nascimento, Igor José, da Silva Rodrigues, Érica Erlanny, da Silva, Manuele Figueiredo, de Araújo-Júnior, João Xavier, de Moura, Ricardo Olimpio

“…The Flaviviridae virus family consists of the genera Hepacivirus, Pestivirus, and Flavivirus, with approximately 70 viral types that use arthropods as vectors…”
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An electrochemical biosensor based on Hairpin-DNA modified gold electrode for detection of DNA damage by a hybrid cancer drug intercalation by Lozano Untiveros, Katherine, da Silva, Emanuella Gomes, de Abreu, Fabiane Caxico, da Silva-Júnior, Edeildo Ferreira, de Araújo-Junior, João Xavier, Mendoça de Aquino, Thiago, Armas, Stephanie M., de Moura, Ricardo Olímpio, Mendonça-Junior, Francisco J.B., Serafim, Vanessa Lima, Chumbimuni-Torres, Karin

“…An efficient and new electrochemical biosensor for detection of DNA damage, induced by the interaction of the hybrid anti-cancer compound (7ESTAC01) with DNA,…”
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Development of a Polymeric Membrane Impregnated with Poly-Lactic Acid (PLA) Nanoparticles Loaded with Red Propolis (RP) by da Costa Silva, Valdemir, do Nascimento, Ticiano G., Mergulhão, Naianny L. O. N., Freitas, Johnnatan D., Duarte, Ilza Fernanda B., de Bulhões, Laisa Carolina G., Dornelas, Camila B., de Araújo, João Xavier, dos Santos, Jucenir, Silva, Anielle C. A., Basílio, Irinaldo D., Goulart, Marilia O. F.

“…The main objectives of this study were to develop and characterize hydrophilic polymeric membranes impregnated with poly-lactic acid (PLA) nanoparticles (NPs)…”
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Antinociceptive and anti-inflammatory activity from algae of the genus Caulerpa by da Matta, Carolina Babosa Brito, de Souza, Everton Tenório, de Queiroz, Aline Cavalcanti, de Lira, Daysianne Pereira, de Araújo, Morgana Vital, Cavalcante-Silva, Luiz Henrique Agra, de Miranda, George Emmanuel C, de Araújo-Júnior, João Xavier, Barbosa-Filho, José Maria, de Oliveira Santos, Bárbara Viviana, Alexandre-Moreira, Magna Suzana

“…Marine natural products have been the focus of discovery for new products of chemical and pharmacological interest. The aim of this study was to evaluate the…”
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Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors by Nascimento, Igor José dos Santos, Santos-Júnior, Paulo Fernando da Silva, Aquino, Thiago Mendonça de, Araújo-Júnior, João Xavier de, Silva-Júnior, Edeildo Ferreira da

“…Over recent years, many outbreaks caused by (re)emerging RNA viruses have been reported worldwide, including life-threatening Flaviviruses, such as Dengue…”
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Sterol 14α-Demethylase from Trypanosomatidae Parasites as a Promising Target for Designing New Antiparasitic Agents by da Silva Santos-Júnior, Paulo Fernando, Schmitt, Martine, de Araújo-Júnior, João Xavier, da Silva-Júnior, Edeildo Ferreira

“…Trypanosomatidae family belongs to the Kinetoplastida order, which consists of obligatory parasites that affect plants and all classes of vertebrates,…”
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Cardioprotective effects induced by hydroalcoholic extract of leaves of Alpinia zerumbet on myocardial infarction in rats by Paulino, Emanuel Tenório, Barros Ferreira, Amanda Karine, da Silva, Jessyka Carolina Galvão, Ferreira Costa, Cintia Danielli, Smaniotto, Salete, de Araújo-Júnior, João Xavier, Silva Júnior, Edeíldo Ferreira, Bortoluzzi, Janaína Herbele, Nogueira Ribeiro, Êurica Adélia

“…The leaves of Alpinia zerumbet is used in folk medicine in Brazil to treat hypertension. However, the cardioprotective effect of this plant has not been…”
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Kopsanone inhibits proliferation and migration of invasive colon cancer cells by Bonfim, Daniella Paiva, Nakamura, Celso Vataru, Araújo Júnior, João Xavier, Pessini, Greisiele Lorena, Leite, Paulo Emílio Correa, Morgado‐Díaz, José Andrés, Leve, Fernanda

“…Colorectal cancer (CRC) is the second leading cause of cancer‐related death globally. In spite of the increasing knowledge on molecular characteristics of…”
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Revealing Insights into Natural Products Against mcr-1-Producing Bacteria by Dos Santos, Ana Beatriz Souza Flor, da Silva, Manuele Figueiredo, de Araújo-Júnior, João Xavier, da Silva-Júnior, Edeildo Ferreira

“…Bacterial resistance has become a major global concern, affecting about 500, 000 individuals in 22 countries. Thus, it is clear that Gram-negative bacteria…”
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Interaction between bioactive compound 11a-N-tosyl-5-deoxi-pterocarpan (LQB-223) and Calf thymus DNA: Spectroscopic approach, electrophoresis and theoretical studies by Silva, Marina M., Nascimento, Eduarda O.O., Silva, Edeíldo F., Araújo, João Xavier de, Santana, Camilla C., Grillo, Luciano Aparecido M., de Oliveira, Rafaela S., R.R.Costa, Paulo, Buarque, Camilla D., Santos, Josué Carinhanha C., Figueiredo, Isis M.

“…The interaction of small molecules with DNA has been quite important, since this biomolecule is currently the major target for a wide range of drugs in…”
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Targeting Chikungunya Virus Entry: Alternatives for New Inhibitors in Drug Discovery by Silva, Leandro Rocha, Rodrigues, Érica Erlanny da Silva, Taniele-Silva, Jamile, Anderson, Letícia, Araújo-Júnior, João Xavier de, Bassi, Ênio José, Silva-Júnior, Edeildo F da

“…Chikungunya virus (CHIKV) is an Alphavirus (Togaviridae) responsible for Chikungunya fever (CHIKF) that is mainly characterized by a severe polyarthralgia, in…”
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A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosis by Santos-Júnior, Paulo Fernando da Silva, Batista, Vitoria de Melo, Nascimento, Igor José dos Santos, Nunes, Isabelle Cavalcante, Silva, Leandro Rocha, Costa, Clara Andrezza Crisóstomo Bezerra, Freitas, Johnnatan Duarte de, Quintans-Júnior, Lucindo José, Araújo-Júnior, João Xavier de, Freitas, Maria Eugênia G. de, Zhan, Peng, Green, Keith D., Garneau-Tsodikova, Sylvie, Mendonça-Júnior, Francisco Jaime Bezerra, Rodrigues-Junior, Valnês S., Silva-Júnior, Edeildo Ferreira da

“…[Display omitted] Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which remains a significant global health challenge…”
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Bradykinin-target therapies in SARS-CoV-2 infection: current evidence and perspectives by da Silva, Manuele Figueiredo, de Araújo-Júnior, João Xavier, da Silva-Júnior, Edeildo Ferreira, Heimfarth, Luana, Martins-Filho, Paulo Ricardo, Quintans, Jullyana de Souza Siqueira, Quintans-Júnior, Lucindo José

“…Coronavirus disease 2019 (COVID-19) is a potentially fatal disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that…”
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Molecular Docking Studies Applied to a Dataset of Cruzain Inhibitors by da Silva-Junior, Edeildo Ferreira, Barcellos Franca, Paulo Henrique, Ribeiro, Frederico Favaro, Bezerra Mendonca-Junior, Francisco Jaime, Scotti, Luciana, Scotti, Marcus Tullius, de Aquino, Thiago Mendonca, de Araujo-Junior, Joao Xavier

“…Chagas' disease is one of the main causes of heart failure in developing countries. The disadvantages of current therapy include the undesirable side-effects,…”
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Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design by Azevedo de Brito, Wanessa, Gomes Dantas, Monique, Andrade Nogueira, Fernando Henrique, Ferreira da Silva-Júnior, Edeildo, Xavier de Araújo-Júnior, João, Aquino, Thiago Mendonça de, Adélia Nogueira Ribeiro, Êurica, da Silva Solon, Lilian Grace, Soares Aragão, Cícero Flávio, Barreto Gomes, Ana Paula

“…Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an…”
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