Search Results - "de Araújo, Fillipe M."

Role of Microgliosis and NLRP3 Inflammasome in Parkinson’s Disease Pathogenesis and Therapy by de Araújo, Fillipe M., Cuenca-Bermejo, Lorena, Fernández-Villalba, Emiliano, Costa, Silvia L., Silva, Victor Diogenes A., Herrero, Maria Trinidad

“…Parkinson's disease (PD) is a neurodegenerative disorder marked primarily by motor symptoms such as rigidity, bradykinesia, postural instability and resting…”
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Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices by Ferreira, Rafael S., Teles-Souza, Jéssica, dos Santos Souza, Cleide, Pereira, Érica P. L., de Araújo, Fillipe M., da Silva, Alessandra Bispo, Castro e Silva, Juliana H., Nonose, Yasmine, Núñez-Figueredo, Yanier, de Assis, Adriano M., Souza, Diogo O., Costa, Maria de Fátima D., Moreira, José Cláudio F., Costa, Silvia L., da Silva, Victor D. A.

“…Rutin is an important flavonoid consumed in the daily diet. It is also known as vitamin P and has been extensively investigated due to its pharmacological…”
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The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome by Dos Santos, Balbino Lino, Dos Santos, Cleonice Creusa, Soares, Janaina R P, da Silva, Karina C, de Oliveira, Juciele Valeria R, Pereira, Gabriele S, de Araújo, Fillipe M, Costa, Maria de Fátima D, David, Jorge Mauricio, da Silva, Victor Diogenes A, Butt, Arthur Morgan, Costa, Silvia Lima

“…Agathisflavone, purified from (Tul.) has been shown to be neuroprotective in in vitro models of glutamate-induced excitotoxicity and inflammatory damage…”
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Aminochrome decreases NGF, GDNF and induces neuroinflammation in organotypic midbrain slice cultures by de Araújo, Fillipe M., Ferreira, Rafael S., Souza, Cleide S., dos Santos, Cleonice Creusa, Rodrigues, Tácio L.R.S., e Silva, Juliana Helena C., Gasparotto, Juciano, Gelain, Daniel Pens, El-Bachá, Ramon S., D. Costa, Maria de Fátima, Fonseca, José Claudio M., Segura-Aguilar, Juan, Costa, Silvia L., Silva, Victor Diogenes A.

“…•Aminochrome induces toxicity in midbrain slice cultures.•Aminochrome induces neuroinflammation in midbrain slice cultures.•Aminochrome reduces NGF and GDNF…”
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Monocrotaline induces acutely cerebrovascular lesions, astrogliosis and neuronal degeneration associated with behavior changes in rats: A model of vascular damage in perspective by Silva, Adriana L., Oliveira, Joana L., do Nascimento, Ravena P., Santos, Letícia O., de Araújo, Fillipe M., dos Santos, Balbino L., Santana, Rejane C., Moreira, Eduardo Luiz T., Batatinha, Maria José M., Alves, Iura M., Velozo, Eudes S., Victor, Mauricio M., Assis, Adriano M., Almeida, Roberto F., de Souza, Diogo O.G., Silva, Victor Diógenes A., Costa, Silvia L.

“…Pyrrolizidine alkaloids (PAs) are secondary plant metabolites playing an important role as phytotoxins in the plant defense mechanisms and can be present as…”
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Autophagy protects against neural cell death induced by piperidine alkaloids present in Prosopis juliflora (Mesquite) by Silva, Victor D A, Cuevas, Carlos, Muñoz, Patricia, Villa, Monica, Ahumada-Castro, Ulises, Huenchuguala, Sandro, Santos, Cleonice C Dos, Araujo, Fillipe M DE, Ferreira, Rafael S, Silva, Vanessa B DA, Silva, Juliana H C E, Soares, Érica N, Velozo, Eudes S, Segura-Aguilar, Juan, Costa, Silvia L

“…Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be…”
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