Search Results - "de Almeida, M. F."

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy by Barceló-Coblijn, Gwendolyn, Martin, Maria Laura, de Almeida, Rodrigo F. M, Noguera-Salvà, Maria Antònia, Marcilla-Etxenike, Amaia, Guardiola-Serrano, Francisca, Lüth, Anja, Kleuser, Burhard, Halver, John E, Escribá, Pablo V

“…The mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent antitumor compound, has not yet been fully elucidated. Here, we show that human cancer cells…”
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Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity by Demoro, Bruno, Bento-Oliveira, Andreia, Marques, Fernanda, Costa Pessoa, João, Otero, Lucía, Gambino, Dinorah, F M de Almeida, Rodrigo, Tomaz, Ana Isabel

“…The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite…”
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Evaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives by Alguacil, Andres, Scalambra, Franco, Romerosa, Antonio, Bento-Oliveira, Andreia, Marques, Fernanda, Maximiano, Ines, de Almeida, Rodrigo F. M., Tomaz, Ana Isabel, Valente, Andreia

“…Piano-stool-{CpRu} complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA), N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA), and…”
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Influence of Lemongrass Essential Oil ( Cymbopogon flexuosus ) Supplementation on Diabetes in Rat Model by Júnior, Ailton S S, Aidar, Felipe J, Silva, Luiz A S, de B Silva, Thais, de Almeida, Sara F M, Teles, Daiane C S, de L Junior, Waldecy, Schimieguel, Dulce M, de Souza, Daniel A, Nascimento, Ana C S, Camargo, Enilton A, Dos Santos, Jymmys L, de O E Silva, Ana M, de S Nunes, Rogéria, Borges, Lysandro P, Lira, Ana A M

“…(1) Background: Species of the genus and its essential oil are known for their antioxidant and hypoglycemic effects. This study aimed to investigate the impact…”
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Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes by Dias, Catarina, Pais, João P., Nunes, Rafael, Blázquez-Sánchez, Maria-Teresa, Marquês, Joaquim T., Almeida, Andreia F., Serra, Patrícia, Xavier, Nuno M., Vila-Viçosa, Diogo, Machuqueiro, Miguel, Viana, Ana S., Martins, Alice, Santos, Maria S., Pelerito, Ana, Dias, Ricardo, Tenreiro, Rogério, Oliveira, Maria C., Contino, Marialessandra, Colabufo, Nicola A., de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…Anthrax is an infectious disease caused by Bacillus anthracis , a bioterrorism agent that develops resistance to clinically used antibiotics. Therefore,…”
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Development of lysosome-mimicking vesicles to study the effect of abnormal accumulation of sphingosine on membrane properties by Carreira, Ana C., de Almeida, Rodrigo F. M., Silva, Liana C.

“…Synthetic systems are widely used to unveil the molecular mechanisms of complex cellular events. Artificial membranes are key examples of models employed to…”
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New anticandidal Cu(i) complexes with neocuproine and ketoconazole derived diphenyl(aminomethyl)phosphane: luminescence properties for detection in fungal cells by Starosta, Radosław, de Almeida, Rodrigo F M, Puchalska, Małgorzata, Białońska, Agata, Panek, Jarosław J, Jezierska, Aneta, Szmigiel, Ida, Suchodolski, Jakub, Krasowska, Anna

“…The search for new antifungals is very important because the large genetic variation of pathogenic organisms has resulted in the development of increasingly…”
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C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations by de Matos, Ana Marta, Blázquez-Sánchez, Maria Teresa, Sousa, Carla, Oliveira, Maria Conceição, de Almeida, Rodrigo F. M., Rauter, Amélia P.

“…The concept of Pan-Assay Interference Compounds (PAINS) is regarded as a threat to the recognition of the broad bioactivity of natural products. Based on the…”
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Unveiling the Mechanism of Action of 7α-acetoxy-6β-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions by Pereira, Filipe, Figueiredo, Teresa, de Almeida, Rodrigo F M, Antunes, Catarina A C, Garcia, Catarina, Reis, Catarina P, Ascensão, Lia, Sobral, Rita G, Rijo, Patricia

“…The number of cases of failure in the treatment of infections associated with resistant bacteria is on the rise, due to the decreasing efficacy of current…”
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Formation of Ceramide/Sphingomyelin Gel Domains in the Presence of an Unsaturated Phospholipid: A Quantitative Multiprobe Approach by Castro, Bruno M., de Almeida, Rodrigo F.M., Silva, Liana C., Fedorov, Alexander, Prieto, Manuel

“…To better understand how ceramide modulates the biophysical properties of the membrane, the interactions between palmitoyl-ceramide (PCer) and…”
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Complexity of Lipid Domains and Rafts in Giant Unilamellar Vesicles Revealed by Combining Imaging and Microscopic and Macroscopic Time-Resolved Fluorescence by de Almeida, Rodrigo F.M., Borst, JanWillem, Fedorov, Alexander, Prieto, Manuel, Visser, Antonie J.W.G.

“…The application of fluorescence lifetime imaging microscopy to study gel/fluid and raftlike lipid domains in giant unilamellar vesicles (GUVs) is demonstrated…”
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Lateral Distribution of the Transmembrane Domain of Influenza Virus Hemagglutinin Revealed by Time-resolved Fluorescence Imaging by Scolari, Silvia, Engel, Stephanie, Krebs, Nils, Plazzo, Anna Pia, De Almeida, Rodrigo F.M., Prieto, Manuel, Veit, Michael, Herrmann, Andreas

“…Influenza virus hemagglutinin (HA) has been suggested to be enriched in liquid-ordered lipid domains named rafts, which represent an important step in virus…”
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Protein substitutes for phenylketonuria in Europe: access and nutritional composition by Pena, M J, de Almeida, M F, van Dam, E, Ahring, K, Bélanger-Quintana, A, Dokoupil, K, Gokmen-Ozel, H, Lammardo, A M, MacDonald, A, Robert, M, Rocha, J C

“…Background/Objectives: Protein substitutes (PS) are an essential component in the dietary management of phenylketonuria (PKU). PS are available as…”
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Biophysical Implications of Sphingosine Accumulation in Membrane Properties at Neutral and Acidic pH by Zupancic, Eva, Carreira, Ana C, de Almeida, Rodrigo F. M, Silva, Liana C

“…Sphingosine (Sph) is a simple lipid involved in the regulation of several biological processes. When accumulated in the late endosomal/lysosomal compartments,…”
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Sphingomyelin/Phosphatidylcholine/Cholesterol Phase Diagram: Boundaries and Composition of Lipid Rafts by de Almeida, Rodrigo F.M., Fedorov, Aleksandre, Prieto, Manuel

“…The ternary system palmitoylsphingomyelin (PSM)/palmitoyloleoylphosphatidylcholine (POPC)/cholesterol is used to model lipid rafts. The phase behavior of the…”
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Evidence for divergent evolution of growth temperature preference in sympatric Saccharomyces species by Gonçalves, Paula, Valério, Elisabete, Correia, Cláudia, de Almeida, João M G C F, Sampaio, José Paulo

“…The genus Saccharomyces currently includes eight species in addition to the model yeast Saccharomyces cerevisiae, most of which can be consistently isolated…”
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A route to understanding yeast cellular envelope – plasma membrane lipids interplaying in cell wall integrity by Almeida, Rodrigo F. M.

“…Sphingolipids and sterols are major components of the plasma membrane in eukaryotic cells. A recent study provides new insight into the intricate but…”
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New diphenylphosphane derivatives of ketoconazole are promising antifungal agents by de Almeida, Rodrigo F. M., Santos, Filipa C., Marycz, Krzysztof, Alicka, Michalina, Krasowska, Anna, Suchodolski, Jakub, Panek, Jarosław J., Jezierska, Aneta, Starosta, Radosław

“…Four new derivatives of ketoconazole ( Ke ) were synthesized: diphenylphosphane ( KeP ), and phosphane chalcogenides: oxide ( KeOP ), sulphide ( KeSP ) and…”
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Ceramide-Domain Formation and Collapse in Lipid Rafts: Membrane Reorganization by an Apoptotic Lipid by Silva, Liana C., de Almeida, Rodrigo F.M., Castro, Bruno M., Fedorov, Alexander, Prieto, Manuel

“…The effect of physiologically relevant ceramide concentrations (≤4 mol %) in raft model membranes with a lipid composition resembling that of cell membranes,…”
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Proactive management of extreme prematurity: disagreement between obstetricians and neonatologists by Guinsburg, R, Branco de Almeida, M F, dos Santos Rodrigues Sadeck, L, Marba, S T M, Suppo de Souza Rugolo, L M, Luz, J H, de Andrade Lopes, J M, Martinez, F E, Procianoy, R S

“…Objective: To verify, in extremely preterm infants, if disagreement between obstetricians and neonatologists regarding proactive management is associated with…”
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