Search Results - "de Abreu Neto, Mario Soares"

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    Approaches for recombinant human factor IX production in serum-free suspension cultures by do Amaral, Robson Luis Ferraz, de Sousa Bomfim, Aline, de Abreu-Neto, Mário Soares, Picanço-Castro, Virgínia, de Sousa Russo, Elisa Maria, Covas, Dimas Tadeu, Swiech, Kamilla

    Published in Biotechnology letters (01-03-2016)
    “…OBJECTIVE: To establish a serum-free suspension process for production of recombinant human factor IX (rhFIX) based on the human cell line HEK 293T by…”
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    Journal Article
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    Human cell lines: A promising alternative for recombinant FIX production by de Sousa Bomfim, Aline, Cristina Corrêa de Freitas, Marcela, Picanço-Castro, Virgínia, de Abreu Soares Neto, Mário, Swiech, Kamilla, Tadeu Covas, Dimas, Maria de Sousa Russo, Elisa

    Published in Protein expression and purification (01-05-2016)
    “…Factor IX (FIX) is a vitamin K-dependent protein, and it has become a valuable pharmaceutical in the Hemophilia B treatment. We evaluated the potential of…”
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    Journal Article
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    Optimized Production of Lentiviral Vectors for CAR-T Cell by Moço, Pablo Diego, de Abreu Neto, Mário Soares, Fantacini, Daianne Maciely Carvalho, Picanço-Castro, Virgínia

    “…Advances in the use of lentiviral vectors for gene therapy applications have created a need for large-scale manufacture of clinical-grade viral vectors for…”
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    The F309S mutation increases factor VIII secretion in human cell line by Fantacini, Daianne Maciely Carvalho, Fontes, Aparecida Maria, de Abreu Neto, Mário Soares, Covas, Dimas Tadeu, Picanço-Castro, Virgínia

    “…The capacity of a human cell line to secrete recombinant factor VIII with a F309S point mutation was investigated, as was the effect of the addition of…”
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    Journal Article