Functional Properties of Lactobacillus mucosae Strains Isolated from Brazilian Goat Milk

The search for probiotic candidates among lactic acid bacteria (LAB) isolated from food may uncover new strains with promising health and technological properties. Lactobacillus mucosae strains attracted recent research attention due to their ability to adhere to intestinal mucus and to inhibit path...

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Bibliographic Details
Published in:	Probiotics and antimicrobial proteins Vol. 9; no. 3; pp. 235 - 245
Main Authors:	de Moraes, Georgia Maciel Dias, de Abreu, Louricélia Rodrigues, do Egito, Antônio Silvio, Salles, Hévila Oliveira, da Silva, Liana Maria Ferreira, Nero, Luís Augusto, Todorov, Svetoslav Dimitrov, dos Santos, Karina Maria Olbrich
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-09-2017
Subjects:	Animals Anti-Bacterial Agents - pharmacology Applied Microbiology Bacterial Adhesion - genetics Bacterial Proteins - genetics Bacterial Proteins - metabolism Bile Acids and Salts - metabolism Biogenic Amines - biosynthesis Brazil Chemistry Chemistry and Materials Science Chemistry/Food Science Drug Resistance, Multiple, Bacterial Food Microbiology Gastrointestinal Tract - metabolism Gastrointestinal Tract - microbiology Gelatinases - biosynthesis Genes, Bacterial Goats Hydrophobic and Hydrophilic Interactions Lactobacillus - genetics Lactobacillus - isolation & purification Lactobacillus - physiology Microbiology Milk - microbiology Nutrition Probiotics - isolation & purification Protein Science Virulence Factors - genetics Lactic acid bacteria Probiotic potential Technological properties LAB Virulence genes Lactobacillus mucosae
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Summary:	The search for probiotic candidates among lactic acid bacteria (LAB) isolated from food may uncover new strains with promising health and technological properties. Lactobacillus mucosae strains attracted recent research attention due to their ability to adhere to intestinal mucus and to inhibit pathogens in the gastrointestinal tract, both related to a probiotic potential. Properties of interest and safety aspects of three Lb. mucosae strains (CNPC006, CNPC007, and CNPC009) isolated from goat milk were investigated employing in vitro tests. The presence of genetic factors related to bile salt hydrolase production ( bsh ), intestinal adhesion properties ( msa , map , mub , and ef-tu ), virulence, and biogenic amine production were also verified. All strains exhibited the target map , mub , and ef-tu sequences; the msa gene was detected in CNPC006 and CNPC007 strains. Some of the searched sequences for virulence factors were detected, especially in the CNPC009 strain; all strains carried the hyl gene, related to the production of hyaluronidase. Lb. mucosae CNPC007 exhibited a high survival rate in simulated gastric and enteric conditions. Besides, all strains exhibited the bsh sequence, and CNPC006 and CNPC007 were able to deconjugate salts of glycodeoxycholic acid (GDC). Regarding technological properties for dairy product applications, a relatively higher milk acidification and clotting capacity, diacetyl production, and proteolytic activity were registered for CNPC007 in comparison to the other strains. Collectively, the results aim at Lb. mucosae CNPC007 as a promising probiotic candidate for application in dairy products, deserving further studies to confirm and explore its potential.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1867-1306 1867-1314
DOI:	10.1007/s12602-016-9244-8