Search Results - "de A. Vallim, Thomas Q"

chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development by Sharp, Tyson V, Al-Attar, Ahmad, Foxler, Daniel E, Ding, Li, de A. Vallim, Thomas Q, Zhang, Yining, Nijmeh, Hala S, Webb, Thomas M, Nicholson, Andrew G, Zhang, Qunyuan, Kraja, Aldi, Spendlove, Ian, Osborne, John, Mardis, Elaine, Longmore, Gregory D

“…Loss of heterozygosity (LOH) and homozygous deletions at chromosome 3p21.3 are common in both small and nonsmall cell lung cancers, indicating the likely…”
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PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1 by Foxler, Daniel E., James, Victoria, Shelton, Samuel J., Vallim, Thomas Q. de A., Shaw, Peter E., Sharp, Tyson V.

“…LIMD1 is a tumour suppressor gene (TSG) down regulated in ∼80% of lung cancers with loss also demonstrated in breast and head and neck squamous cell…”
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