Search Results - "de Wouters, Tomas"

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome by Shoaie, Saeed, Ghaffari, Pouyan, Kovatcheva-Datchary, Petia, Mardinoglu, Adil, Sen, Partho, Pujos-Guillot, Estelle, de Wouters, Tomas, Juste, Catherine, Rizkalla, Salwa, Chilloux, Julien, Hoyles, Lesley, Nicholson, Jeremy K., Dore, Joel, Dumas, Marc E., Clement, Karine, Bäckhed, Fredrik, Nielsen, Jens

“…The human gut microbiome is known to be associated with various human disorders, but a major challenge is to go beyond association studies and elucidate…”
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Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites by Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Geirnaert, Annelies, Prantil-Baun, Rachelle, Camacho, Diogo M, Chou, David B, Jalili-Firoozinezhad, Sasan, de Wouters, Tomás, Kasendra, Magdalena, Super, Michael, Cartwright, Mark J, Richmond, Camilla A, Breault, David T, Lacroix, Christophe, Ingber, Donald E

“…Species-specific differences in tolerance to infection are exemplified by the high susceptibility of humans to enterohemorrhagic Escherichia coli (EHEC)…”
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Stratification of human gut microbiomes by succinotype is associated with inflammatory bowel disease status by Anthamatten, Laura, von Bieberstein, Philipp Rogalla, Menzi, Carmen, Zünd, Janina N, Lacroix, Christophe, de Wouters, Tomas, Leventhal, Gabriel E

“…The human gut microbiome produces and consumes a variety of compounds that interact with the host and impact health. Succinate is of particular interest as it…”
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Probiotics tailored to the infant: a window of opportunity by Chassard, Christophe, de Wouters, Tomas, Lacroix, Christophe

“…Graphical abstract…”
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GABA Production by Human Intestinal Bacteroides spp.: Prevalence, Regulation, and Role in Acid Stress Tolerance by Otaru, Nize, Ye, Kun, Mujezinovic, Denisa, Berchtold, Laura, Constancias, Florentin, Cornejo, Fabián A, Krzystek, Adam, de Wouters, Tomas, Braegger, Christian, Lacroix, Christophe, Pugin, Benoit

“…The high neuroactive potential of metabolites produced by gut microbes has gained traction over the last few years, with metagenomic-based studies suggesting…”
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Understanding the prebiotic potential of different dietary fibers using an in vitro continuous adult fermentation model (PolyFermS) by Poeker, Sophie A., Geirnaert, Annelies, Berchtold, Laura, Greppi, Anna, Krych, Lukasz, Steinert, Robert E., de Wouters, Tomas, Lacroix, Christophe

“…Consumption of fermentable dietary fibers (DFs), which can induce growth and/or activity of specific beneficial populations, is suggested a promising strategy…”
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Microbiome-based interventions to modulate gut ecology and the immune system by Hitch, Thomas C. A., Hall, Lindsay J., Walsh, Sarah Kate, Leventhal, Gabriel E., Slack, Emma, de Wouters, Tomas, Walter, Jens, Clavel, Thomas

“…The gut microbiome lies at the intersection between the environment and the host, with the ability to modify host responses to disease-relevant exposures and…”
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A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity by Wylensek, David, Hitch, Thomas C. A., Riedel, Thomas, Afrizal, Afrizal, Kumar, Neeraj, Wortmann, Esther, Liu, Tianzhe, Devendran, Saravanan, Lesker, Till R., Hernández, Sara B., Heine, Viktoria, Buhl, Eva M., M. D’Agostino, Paul, Cumbo, Fabio, Fischöder, Thomas, Wyschkon, Marzena, Looft, Torey, Parreira, Valeria R., Abt, Birte, Doden, Heidi L., Ly, Lindsey, Alves, João M. P., Reichlin, Markus, Flisikowski, Krzysztof, Suarez, Laura Navarro, Neumann, Anthony P., Suen, Garret, de Wouters, Tomas, Rohn, Sascha, Lagkouvardos, Ilias, Allen-Vercoe, Emma, Spröer, Cathrin, Bunk, Boyke, Taverne-Thiele, Anja J., Giesbers, Marcel, Wells, Jerry M., Neuhaus, Klaus, Schnieke, Angelika, Cava, Felipe, Segata, Nicola, Elling, Lothar, Strowig, Till, Ridlon, Jason M., Gulder, Tobias A. M., Overmann, Jörg, Clavel, Thomas

“…Our knowledge about the gut microbiota of pigs is still scarce, despite the importance of these animals for biomedical research and agriculture. Here, we…”
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Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells by Nepelska, Malgorzata, de Wouters, Tomas, Jacouton, Elsa, Béguet-Crespel, Fabienne, Lapaque, Nicolas, Doré, Joël, Arulampalam, Velmurugesan, Blottière, Hervé M.

“…In healthy subjects, the intestinal microbiota interacts with the host’s epithelium, regulating gene expression to the benefit of both, host and microbiota…”
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Adhesion Potential of Intestinal Microbes Predicted by Physico-Chemical Characterization Methods by de Wouters, Tomas, Jans, Christoph, Niederberger, Tobias, Fischer, Peter, Rühs, Patrick Alberto

“…Bacterial adhesion to epithelial surfaces affects retention time in the human gastro-intestinal tract and therefore significantly contributes to interactions…”
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High Iron-Sequestrating Bifidobacteria Inhibit Enteropathogen Growth and Adhesion to Intestinal Epithelial Cells In vitro by Vazquez-Gutierrez, Pamela, de Wouters, Tomas, Werder, Julia, Chassard, Christophe, Lacroix, Christophe

“…The gut microbiota plays an important role in host health, in particular by its barrier effect and competition with exogenous pathogenic bacteria. In the…”
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Commensal Streptococcus salivarius Modulates PPARγ Transcriptional Activity in Human Intestinal Epithelial Cells by Couvigny, Benoît, de Wouters, Tomas, Kaci, Ghalia, Jacouton, Elsa, Delorme, Christine, Doré, Joël, Renault, Pierre, Blottière, Hervé M, Guédon, Eric, Lapaque, Nicolas

“…The impact of commensal bacteria in eukaryotic transcriptional regulation has increasingly been demonstrated over the last decades. A multitude of studies have…”
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Stepwise Development of an in vitro Continuous Fermentation Model for the Murine Caecal Microbiota by Poeker, Sophie A, Lacroix, Christophe, de Wouters, Tomas, Spalinger, Marianne R, Scharl, Michael, Geirnaert, Annelies

“…Murine models are valuable tools to study the role of gut microbiota in health or disease. However, murine and human microbiota differ in species composition,…”
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ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways by Korecka, Agata, de Wouters, Tomas, Cultrone, Antonietta, Lapaque, Nicolas, Pettersson, Sven, Doré, Joël, Blottière, Hervé M, Arulampalam, Velmurugesan

“…Short-chain fatty acids (SCFAs), such as butyrate and propionate, are metabolic products of carbohydrate fermentation by the microbiota and constitute the main…”
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Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP) by Kurt, Fabienne, Leventhal, Gabriel E, Spalinger, Marianne Rebecca, Anthamatten, Laura, Rogalla von Bieberstein, Philipp, Menzi, Carmen, Reichlin, Markus, Meola, Marco, Rosenthal, Florian, Rogler, Gerhard, Lacroix, Christophe, de Wouters, Tomas

“…The success of fecal microbiota transplants (FMT) has provided the necessary proof-of-concept for microbiome therapeutics. Yet, feces-based therapies have many…”
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A MALDI-TOF MS library for rapid identification of human commensal gut bacteria from the class Clostridia by Asare, Paul Tetteh, Lee, Chi-Hsien, Hürlimann, Vera, Teo, Youzheng, Cuénod, Aline, Akduman, Nermin, Gekeler, Cordula, Afrizal, Afrizal, Corthesy, Myriam, Kohout, Claire, Thomas, Vincent, de Wouters, Tomas, Greub, Gilbert, Clavel, Thomas, Pamer, Eric G, Egli, Adrian, Maier, Lisa, Vonaesch, Pascale

“…Microbial isolates from culture can be identified using 16S or whole-genome sequencing which generates substantial costs and requires time and expertise…”
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Corrigendum: A MALDI-TOF MS library for rapid identification of human commensal gut bacteria from the class Clostridia by Asare, Paul Tetteh, Lee, Chi-Hsien, Hürlimann, Vera, Teo, Youzheng, Cuénod, Aline, Akduman, Nermin, Gekeler, Cordula, Afrizal, Afrizal, Corthesy, Myriam, Kohout, Claire, Thomas, Vincent, de Wouters, Tomas, Greub, Gilbert, Clavel, Thomas, Pamer, Eric G, Egli, Adrian, Maier, Lisa, Vonaesch, Pascale

“…[This corrects the article DOI: 10.3389/fmicb.2023.1104707.]…”
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Voices of biotech leaders by Bosley, Katrine, Casebourn, Charlotte, Chan, Priscilla, Chen, Janice, Chen, Michael, Church, George, Cumbers, John, de Wouters, Tomas, Dewey-Hagborg, Heather, Duportet, Xavier, Ene-Obong, Abasi, Elizondo, Arturo, Farrar, Jeremy, Gates, Bill, Gatto, Francesco, Giwa, Sebastian, Godec, Jernej, Gold, Silvia, LeProust, Emily, Lunshof, Jeantine, Martucci, Eddie, Heath, Michelle McMurray, Mellad, Jason, Oudova, Veronika, Oxman, Neri, Regev, Aviv, Richardson, Sarah, Scott, Christopher Thomas, Sherkow, Jake, Sibener, Leah, Tarragó, Teresa, Terry, Sharon, Venter, J. Craig, Wang, Spin, Wickramasekara, Sajith, Yadi, Hakim, Yang, Luhan, Zhao, Bowen

“…Nature Biotechnology asks a selection of leaders from across biotech to look at the future of the sector and make some predictions for the coming years…”
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Publisher Correction: Voices of biotech leaders by Bosley, Katrine, Casebourn, Charlotte, Chan, Priscilla, Chen, Janice, Chen, Michael, Church, George, Cumbers, John, de Wouters, Tomas, Dewey-Hagborg, Heather, Duportet, Xavier, Ene-Obong, Abasi, Elizondo, Arturo, Farrar, Jeremy, Gates, Bill, Gatto, Francesco, Giwa, Sebastian, Godec, Jernej, Gold, Silvia, LeProust, Emily, Lunshof, Jeantine, Martucci, Eddie, Heath, Michelle McMurray, Mellad, Jason, Oudova, Veronika, Oxman, Neri, Regev, Aviv, Richardson, Sarah, Scott, Christopher Thomas, Sherkow, Jake, Sibener, Leah, Tarragó, Teresa, Terry, Sharon, Venter, J. Craig, Wang, Spin, Wickramasekara, Sajith, Yadi, Hakim, Yang, Luhan, Zhao, Bowen

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The NF‐κB binding site located in the proximal region of the TSLP promoter is critical for TSLP modulation in human intestinal epithelial cells by Cultrone, Antonietta, de Wouters, Tomas, Lakhdari, Omar, Kelly, Denise, Mulder, Imke, Logan, Elizabeth, Lapaque, Nicolas, Doré, Joel, Blottière, Hervé M.

“…Thymic stromal lymphopoietin (TSLP) is constitutively secreted by intestinal epithelial cells. It regulates gut DCs, therefore, contributing to the maintenance…”
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