Search Results - "de Morais, Hely"
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1
Akt activation by insulin treatment attenuates cachexia in Walker‐256 tumor‐bearing rats
Published in Journal of cellular biochemistry (01-11-2020)“…Cancer‐bearing often exhibits hypoinsulinemia, insulin (INS) resistance and glutamine depletion associated with cachexia. However, INS and glutamine effects on…”
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2
Decreased hepatic response to glucagon, adrenergic agonists, and cAMP in glycogenolysis, gluconeogenesis, and glycolysis in tumor‐bearing rats
Published in Journal of cellular biochemistry (01-09-2018)“…The response to glucagon and adrenaline in cancer cachexia is poorly known. The aim of this study was to investigate the response to glucagon, adrenergic…”
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3
Peripheral insulin resistance is early, progressive, and correlated with cachexia in Walker‐256 tumor‐bearing rats
Published in Cell biochemistry and function (01-12-2023)“…Insulin (INS) resistance is often found in cancer‐bearing, but its correlation with cachexia development is not completely established. This study investigated…”
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4
Celecoxib and Ibuprofen Restore the ATP Content and the Gluconeogenesis Activity in the Liver of Walker-256 Tumor-Bearing Rats
Published in Cellular physiology and biochemistry (01-01-2015)“…Background/Aims: The main purpose of this study was to investigate the effects of celecoxib and ibuprofen, both non-steroidal anti-inflammatory drugs (NSAIDs),…”
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5
Chronic Glibenclamide Treatment Attenuates Walker-256 Tumour Growth in Prediabetic Obese Rats
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: The sulphonylurea glibenclamide (Gli) is widely used in the treatment of type 2 diabetes. In addition to its antidiabetic effects, low…”
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6
Effects of celecoxib and ibuprofen on metabolic disorders induced by Walker-256 tumor in rats
Published in Molecular and cellular biochemistry (01-01-2015)“…The contribution of anti-inflammatory property of celecoxib in the improvement of metabolic disorders in cancer is unknown. The purpose of this study was to…”
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7
Insulin, not glutamine dipeptide, reduces lipases expression and prevents fat wasting and weight loss in Walker 256 tumor-bearing rats
Published in European journal of pharmacology (05-07-2017)“…Cachexia is the main cause of mortality in advanced cancer patients. We investigated the effects of insulin (INS) and glutamine dipeptide (GDP), isolated or…”
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8
Decreased response to cAMP in the glucose and glycogen catabolism in perfused livers of Walker-256 tumor-bearing rats
Published in Molecular and cellular biochemistry (01-09-2012)“…The hepatic response to cyclic adenosine monophosphate (cAMP) and N6-monobutyryl-cAMP (N6-MB-cAMP) in the glucose and glycogen catabolism and hepatic glycogen…”
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9
Effect of infliximab on metabolic disorders induced by Walker-256 tumor in rats
Published in Pharmacological reports (2013)“…The purpose of this study was to investigate the effect of infliximab, an anti-tumor necrosis factor a (TNFα) mono-clonal antibody, on the progression of…”
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10
Early treatment with metformin induces resistance against tumor growth in adult rats
Published in Cancer biology & therapy (01-01-2015)“…It is known that antidiabetic drug metformin, which is used worldwide, has anti-cancer effects and can be used to prevent cancer growth. We tested the…”
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11
Changes in liver gluconeogenesis during the development of Walker-256 tumour in rats
Published in International journal of experimental pathology (01-02-2013)“…Summary Few studies have investigated liver gluconeogenesis in cancer and there is no agreement as to whether the activity of this pathway is increased or…”
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