Search Results - "de Angelis, Anna"
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Host microbiota constantly control maturation and function of microglia in the CNS
Published in Nature neuroscience (01-07-2015)“…In this study, the authors show that host microbiota play a key role in modulating microglia homeostasis. Germ-free mice or mice with only limited microbiota…”
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Communicating systems in the body: how microbiota and microglia cooperate
Published in Immunology (01-01-2017)“…Summary Microglia are tissue macrophages of the central nervous system (CNS). Their key tasks are immune surveillance as well as responding to infections or…”
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3
Structure of the chemokine receptor CXCR1 in phospholipid bilayers
Published in Nature (London) (29-11-2012)“…NMR spectroscopy is used to determine the three-dimensional structure of the full-length human chemokine receptor CXCR1 in phospholipid bilayers under…”
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4
Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity
Published in PLoS pathogens (18-05-2021)“…SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic…”
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Metal‐ion Binding to Host Defense Peptide Piscidin 3 Observed in Phospholipid Bilayers by Magic Angle Spinning Solid‐state NMR
Published in Chemphyschem (21-01-2019)“…Cationic antimicrobial peptides (AMPs) are essential components of the innate immune system. They have attracted interest as novel compounds with the potential…”
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Effect of GH p.L127V Polymorphism and Feeding Systems on Milk Production Traits and Fatty Acid Composition in Modicana Cows
Published in Animals (Basel) (14-09-2020)“…Growth hormone participates in the regulation of lactation and lipid metabolism. A trial study was conducted to evaluate the effects of genetic polymorphism at…”
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7
Commensal microbiota divergently affect myeloid subsets in the mammalian central nervous system during homeostasis and disease
Published in The EMBO journal (01-12-2021)“…The immune cells of the central nervous system (CNS) comprise parenchymal microglia and at the CNS border regions meningeal, perivascular, and choroid plexus…”
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Amphipathic Antimicrobial Piscidin in Magnetically Aligned Lipid Bilayers
Published in Biophysical journal (07-09-2011)“…The amphipathic antimicrobial peptide piscidin 1 was studied in magnetically aligned phospholipid bilayers by oriented-sample solid-state NMR spectroscopy. 31P…”
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Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl)propanoic acid (HQA)
Published in Journal of biomolecular NMR (01-04-2015)“…The use of paramagnetic constraints in protein NMR is an active area of research because of the benefits of long-range distance measurements (>10 Å). One of…”
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Insect and fish by-products as sustainable alternatives to conventional animal proteins in animal nutrition
Published in Italian journal of animal science (14-12-2020)“…This paper reviews current knowledge on two feedstuffs, that is, insect meal and fish by-products, as alternatives to conventional animal protein sources…”
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11
Bicelle samples for solid-state NMR of membrane proteins
Published in Nature protocols (01-10-2007)“…Magnetically aligned bicelles are an excellent medium for structure determination of isotopically labeled membrane proteins by solid-state NMR spectroscopy…”
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12
A Multipurpose Leguminous Plant for the Mediterranean Countries: Leucaena leucocephala as an Alternative Protein Source: A Review
Published in Animals (Basel) (29-07-2021)“…In tropical and subtropical regions, as well as in the internal and/or marginal Mediterranean areas, one of the most important problems related to animal…”
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13
Structure of monomeric Interleukin-8 and its interactions with the N-terminal Binding Site-I of CXCR1 by solution NMR spectroscopy
Published in Journal of biomolecular NMR (01-11-2017)“…The structure of monomeric human chemokine IL-8 (residues 1–66) was determined in aqueous solution by NMR spectroscopy. The structure of the monomer is similar…”
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14
Interaction of Monomeric Interleukin-8 with CXCR1 Mapped by Proton-Detected Fast MAS Solid-State NMR
Published in Biophysical journal (19-12-2017)“…The human chemokine interleukin-8 (IL-8; CXCL8) is a key mediator of innate immune and inflammatory responses. This small, soluble protein triggers a host of…”
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15
Protein hunger of the feed sector: the alternatives offered by the plant world
Published in Italian journal of animal science (14-12-2020)“…The expected future demand for highly nutrient animal food products will push the animal production system to search for new sources of high-quality protein…”
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Effects of BLG polymorphism and dietary supplementation with carob pulp on ewe milk traits and fatty acid composition
Published in Italian journal of animal science (31-12-2023)“…The current study examined the effect on milk traits and composition of the replacement of barley grain with carob pulp as a supplement for grazing ewes with…”
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Control of Transmembrane Helix Dynamics by Interfacial Tryptophan Residues
Published in Biophysical journal (05-06-2018)“…Transmembrane protein domains often contain interfacial aromatic residues, which may play a role in the insertion and stability of membrane helices. Residues…”
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Mechanically, Magnetically, and “Rotationally Aligned” Membrane Proteins in Phospholipid Bilayers Give Equivalent Angular Constraints for NMR Structure Determination
Published in The journal of physical chemistry. B (11-11-2010)“…The native environment for membrane proteins is the highly asymmetric phospholipid bilayer, and this has a large effect on both their structure and dynamics…”
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19
Assigning solid-state NMR spectra of aligned proteins using isotropic chemical shifts
Published in Journal of magnetic resonance (1997) (01-12-2006)“…A method for assigning solid-state NMR spectra of membrane proteins aligned in phospholipid bicelles that makes use of isotropic chemical shift frequencies and…”
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Leptin Gene Polymorphism in Goats Fed with Diet at Different Energy Level: Effects on Feed Intake, Milk Traits, Milk Fatty Acids Composition, and Metabolic State
Published in Animals (Basel) (06-07-2019)“…The study investigated the effects of a polymorphism at the gene intron 1 microsatellite region and its interaction with diet energy level on feed intake, milk…”
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