Search Results - "daCosta, Jaderson Costa"
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Depression comorbidity in epileptic rats is related to brain glucose hypometabolism and hypersynchronicity in the metabolic network architecture
Published in Epilepsia (Copenhagen) (01-05-2018)“…Summary Objective Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy syndromes in the world. Depression is an important comorbidity of…”
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2
Intra-arterial transplantation of human umbilical cord blood mononuclear cells in neonatal hypoxic–ischemic rats
Published in Life sciences (1973) (06-02-2014)“…Based on preclinical findings, cellular therapy has become a promising therapeutic approach for neonatal hypoxia–ischemia (HI). However, before translation…”
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3
The antidepressant effect of bone marrow mononuclear cell transplantation in chronic stress
Published in Journal of psychopharmacology (Oxford) (01-05-2019)“…Background: Inflammation could be a risk factor for the development of depression and change the outcome of this common chronic-recurrent mental disorder…”
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4
A novel preclinical rodent model of collagenase-induced germinal matrix/intraventricular hemorrhage
Published in Brain research (14-10-2010)“…Abstract Germinal matrix/intraventricular hemorrhage (GMH/IVH) is a complication that arises in premature infants associated with neurological sequelae…”
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5
Identification and immunophenotype of abnormal cells present in focal cortical dysplasia type IIb
Published in Surgical and experimental pathology (20-12-2018)“…Abstract Background Focal cortical dysplasias (FCDs) are malformations of cortical development that present cortical dyslamination and abnormal cell morphology…”
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Two intrathecal transplants of bone marrow mononuclear cells produce motor improvement in an acute and severe model of spinal cord injury
Published in Coluna (01-12-2013)“…OBJECTIVE: We studied transplants of bone marrow mononuclear cells (BMMC) by lumbar puncture (LP) in a severe model of spinal cord injury (SCI) using clip…”
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Migration and Synaptic Aspects of Neurons Derived from Human Induced Pluripotent Stem Cells from Patients with Focal Cortical Dysplasia II
Published in Neuroscience (01-06-2019)“…Malformations of cortical development (MCDs) include many different Central Nervous System (CNS) disorders related to a complex process of cortex formation. In…”
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Neurotoxic mechanisms of glyphosate exposure
Published in Alzheimer's & dementia (01-12-2022)“…Background Human exposure to pesticides is increasing, especially glyphosate‐based herbicides (GBH). Thus, it is of great interest to characterize whether…”
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O uso de células-tronco na asfixia perinatal: do laboratório à prática clínica
Published in Jornal de pediatria (01-12-2010)“…OBJETIVOS: Apresentar evidências científicas recentes sobre os efeitos do transplante com células-tronco em modelos animais de lesão cerebral…”
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10
DNA damage in organs of mice treated acutely with patulin, a known mycotoxin
Published in Food and chemical toxicology (01-10-2012)“…► Genotoxic effect of patulin after systemic administration was evaluated in mice. ► Dose-dependent increase in DNA strand breaks (brain, liver, kidneys) was…”
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Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system
Published in Toxicology (Amsterdam) (30-04-2021)“…•Jack bean ureases, JBU and canatoxin (CNTX), cause seizures in rodents.•Electrophysiology and brain imaging were applied to study their mode of…”
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Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats
Published in Life sciences (1973) (15-08-2011)“…Epilepsy affects 0.5–1% of the world's population, and approximately a third of these patients are refractory to current medication. Given their ability to…”
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13
Transplantation of bone marrow mononuclear cells prolongs survival, delays disease onset and progression and mitigates neuronal loss in pre-symptomatic, but not symptomatic ALS mice
Published in Neuroscience letters (28-10-2016)“…•We investigate the effect of bone marrow mononuclear cells (BMMC) in ALS mice.•Pre-symptomatic BMMC transplantation improves the animal’s clinical…”
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14
Highly palatable diet changes brain glucose metabolism in mice
Published in Alzheimer's & dementia (01-12-2020)“…Background Obesity has become a global public health issue and is knowingly associated with several pathological conditions. Epidemiological data indicate it…”
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Highly palatable diet changes brain glucose metabolism in mice: Prevention (nonpharmacological) / Lifestyle factors (e.g., smoking, etc.)
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background Obesity has become a global public health issue and is knowingly associated with several pathological conditions. Epidemiological data…”
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16
Hemispheric Brain Injury and Behavioral Deficits Induced by Severe Neonatal Hypoxia-Ischemia in Rats Are Not Attenuated by Intravenous Administration of Human Umbilical Cord Blood Cells
Published in Pediatric research (01-06-2009)“…Neonatal hypoxia-ischemia (HI) is an important cause of mortality and morbidity in infants. Human umbilical cord blood (HUCB) is a potential source of cellular…”
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Transplantation of Bone Marrow Mononuclear Cells Modulates Hippocampal Expression of Growth Factors in Chronically Epileptic Animals
Published in CNS neuroscience & therapeutics (01-05-2015)“…Summary Aims In previous studies, transplantation of bone marrow mononuclear cells (BMMCs) in epileptic animals has been found to be neuroprotective. However,…”
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Antidepressant Effects of Ketamine Are Not Related to super(18)F-FDG Metabolism or Tyrosine Hydroxylase Immunoreactivity in the Ventral Tegmental Area of Wistar Rats
Published in Neurochemical research (01-06-2015)“…Major depressive disorder (MDD) is an important health problem that is often associated to stress. One of the main brain regions related to MDD is the ventral…”
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Antidepressant Effects of Ketamine Are Not Related to 18F-FDG Metabolism or Tyrosine Hydroxylase Immunoreactivity in the Ventral Tegmental Area of Wistar Rats
Published in Neurochemical research (01-06-2015)“…Major depressive disorder (MDD) is an important health problem that is often associated to stress. One of the main brain regions related to MDD is the ventral…”
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Antidepressant Effects of Ketamine Are Not Related to ^sup 18^F-FDG Metabolism or Tyrosine Hydroxylase Immunoreactivity in the Ventral Tegmental Area of Wistar Rats
Published in Neurochemical research (01-06-2015)“…Major depressive disorder (MDD) is an important health problem that is often associated to stress. One of the main brain regions related to MDD is the ventral…”
Get full text
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