Search Results - "da Silva Sanches, Paulo Ricardo"
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Antiviral Evaluation of New Synthetic Bioconjugates Based on GA-Hecate: A New Class of Antivirals Targeting Different Steps of Zika Virus Replication
Published in Molecules (Basel, Switzerland) (21-06-2023)“…Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013-2015 Zika virus…”
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Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm
Published in Molecules (Basel, Switzerland) (25-12-2015)“…Decapeptide KSL-W shows antibacterial activities and can be used in the oral cavity, however, it is easily degraded in aqueous solution and eliminated…”
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The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro
Published in Pharmaceuticals (Basel, Switzerland) (30-09-2023)“…Chikungunya virus (CHIKV) belongs to the Alphavirus genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral…”
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GA-Hecate antiviral properties on HCV whole cycle represent a new antiviral class and open the door for the development of broad spectrum antivirals
Published in Scientific reports (25-09-2018)“…In recent years, synthetic peptides have been considered promising targets for drug development that possess low side-effects, are cost-effective and are…”
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The Dimeric Peptide (KKYRYHLKPF)2K Shows Broad-Spectrum Antiviral Activity by Inhibiting Different Steps of Chikungunya and Zika Virus Infection
Published in Viruses (14-05-2023)“…Chikungunya virus (CHIKV) and Zika virus (ZIKV) are important disease-causing agents worldwide. Currently, there are no antiviral drugs or vaccines approved to…”
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Burden of Influenza and Respiratory Syncytial Viruses in Suspected COVID-19 Patients: A Cross-Sectional and Meta-Analysis Study
Published in Viruses (01-03-2023)“…Non-SARS-CoV-2 respiratory viral infections, such as influenza virus (FluV) and human respiratory syncytial virus (RSV), have contributed considerably to the…”
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Advances in drug discovery of flavivirus NS2B-NS3pro serine protease inhibitors for the treatment of Dengue, Zika, and West Nile viruses
Published in Bioorganic chemistry (01-12-2024)“…[Display omitted] Flaviviruses are vector-borne RNA viruses that seriously threaten global public health due to their high transmission index in humans, mainly…”
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Impairment of the class IIa bacteriocin receptor function and membrane structural changes are associated to enterocin CRL35 high resistance in Listeria monocytogenes
Published in Biochimica et biophysica acta. General subjects (01-07-2017)“…Enterocin CRL35 is a class IIa bacteriocin with anti-Listeria activity. Resistance to these peptides has been associated with either the downregulation of the…”
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The Dimeric Peptide [sub.2]K Shows Broad-Spectrum Antiviral Activity by Inhibiting Different Steps of Chikungunya and Zika Virus Infection
Published in Viruses (01-05-2023)“…Chikungunya virus (CHIKV) and Zika virus (ZIKV) are important disease-causing agents worldwide. Currently, there are no antiviral drugs or vaccines approved to…”
Get full text
Journal Article -
10
The Dimeric Peptide (KKYRYHLKPF) 2 K Shows Broad-Spectrum Antiviral Activity by Inhibiting Different Steps of Chikungunya and Zika Virus Infection
Published in Viruses (14-05-2023)“…Chikungunya virus (CHIKV) and Zika virus (ZIKV) are important disease-causing agents worldwide. Currently, there are no antiviral drugs or vaccines approved to…”
Get full text
Journal Article