Salivary flow rate and biochemical composition analysis in stimulated whole saliva of children with cystic fibrosis

Highlights • Children with cystic fibrosis have salivary changes compared to to children without the disease. • Children with cystic fibrosis have reduced salivary flow rate. • Children with cystic fibrosis have reduced amylase and peroxidase activities. • Children with cystic fibrosis have reduced...

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Bibliographic Details
Published in:	Archives of oral biology Vol. 60; no. 11; pp. 1650 - 1654
Main Authors:	da Silva Modesto, Karine Barros, de Godói Simões, Jéssica Bueno, de Souza, Amanda Ferreira, Damaceno, Neiva, Duarte, Danilo Antonio, Leite, Mariana Ferreira, de Almeida, Eliete Rodrigues
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-11-2015
Subjects:	Advanced Basic Science alpha-Amylases - analysis alpha-Amylases - metabolism alpha-Amylases - secretion Buffer capacity Buffers Case-Control Studies Child Cystic fibrosis Cystic Fibrosis - physiopathology Dentistry Female Humans Hydrogen-Ion Concentration Male N-Acetylneuraminic Acid - analysis N-Acetylneuraminic Acid - secretion Peroxidase - analysis Peroxidase - metabolism Peroxidase - secretion Saliva Saliva - chemistry Saliva - secretion Salivary peroxidase Salivary Proteins and Peptides - analysis Salivary Proteins and Peptides - secretion Secretory Rate - physiology Sialic acid Total protein α-Amylase Sialic acid Total protein Buffer capacity Cystic fibrosis α-Amylase Saliva Salivary peroxidase
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Summary:	Highlights • Children with cystic fibrosis have salivary changes compared to to children without the disease. • Children with cystic fibrosis have reduced salivary flow rate. • Children with cystic fibrosis have reduced amylase and peroxidase activities. • Children with cystic fibrosis have reduced sialic acid concentration. • Children with cystic fibrosis have increased total protein concentration.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0003-9969 1879-1506
DOI:	10.1016/j.archoralbio.2015.08.007