Search Results - "da Silva Bitencourt, Claudia"
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TLR2, TLR4 and CD14 recognize venom-associated molecular patterns from Tityus serrulatus to induce macrophage-derived inflammatory mediators
Published in PloS one (07-02-2014)“…Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the…”
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Prostaglandin D2-loaded microspheres effectively activate macrophage effector functions
Published in European journal of pharmaceutical sciences (12-10-2015)“…[Display omitted] Biodegradable lactic-co-glycolic acid (PLGA) microspheres (MS) improve the stability of biomolecules stability and allow enable their…”
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Hyaluronidase-loaded PLGA microparticles as a new strategy for the treatment of pulmonary fibrosis
Published in Tissue engineering. Part A (01-01-2015)“…The aim of this work was to develop an innovative tool for the treatment of pulmonary fibrosis based on our previous findings, which demonstrated that…”
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Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection
Published in Mediators of Inflammation (01-01-2013)“…Prostaglandins act as mediators of inflammation and, similar to cytokines, function as immune modulators during innate and adaptive immune responses…”
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Tityus serrulatus venom and toxins Ts1, Ts2 and Ts6 induce macrophage activation and production of immune mediators
Published in Toxicon (Oxford) (01-06-2011)“…Scorpion envenomation induces a systemic immune response, and neurotoxins of venom act on specific ion channels, modulating neurotransmitter release or…”
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Microspheres prepared with different co-polymers of poly(lactic-glycolic acid) (PLGA) or with chitosan cause distinct effects on macrophages
Published in Colloids and surfaces, B, Biointerfaces (01-12-2015)“…[Display omitted] •Alveolar macrophages (J-774.1) treated with MS prepared with chitosan, and four different co-polymers of PLGA [poly(lactic-co-glycolic…”
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Ts6 and Ts2 from Tityus serrulatus venom induce inflammation by mechanisms dependent on lipid mediators and cytokine production
Published in Toxicon (Oxford) (01-01-2013)“…Inflammatory mediators are thought to be involved in the systemic and local immune response induced by the Tityus serrulatus scorpion envenomation. New…”
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PPAR-γ activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production
Published in Toxicon (Oxford) (01-01-2015)“…Tityus serrulatus venom (TsV) consists of numerous peptides with different physiological and pharmacological activities. Studies have shown that scorpion venom…”
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