Search Results - "da Silva, Luiz Claudio Rodrigues Pereira"

Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods by do Amaral, Lilian Henriques, do Carmo, Flavia Almada, Amaro, Maria Inês, de Sousa, Valeria Pereira, da Silva, Luiz Claudio Rodrigues Pereira, de Almeida, Gabriella Silva, Rodrigues, Carlos Rangel, Healy, Anne Marie, Cabral, Lucio Mendes

“…In this study, the formation of caffeine/dapsone (CAF/DAP) cocrystals by scalable production methods, such as liquid-assisted grinding (LAG) and spray drying,…”
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Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives by Viana, Gil Mendes, Soares, Deivid Costa, Santana, Marcos Vinicius, Amaral, Lilian Henriques do, Meireles, Paloma Wetler, Nunes, Raquel Pinto, Luiz Cláudio Rodrigues Pereira da Silva, Lúcia Cruz de Sequeira Aguiar, Rodrigues, Carlos Rangel, Sousa, Valeria Pereira de, Castro, Helena Carla, Abreu, Paula Alvarez, Sathler, Plínio Cunha, Saraiva, Elvira Maria, Cabral, Lucio Mendes

“…Leishmaniasis is a neglected tropical disease caused by protozoan parasites belonging to the genus Leishmania. Currently, the drugs available for treatment of…”
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Targeted Nanosystems to Prostate Cancer by da Silva, Luiz Cláudio Rodrigues Pereira, Carmoa, Flávia Almada do, Nasciutti, Luiz Eurico, Zancan, Patrícia, Sathler, Plínio Cunha, Cabral, Lucio Mendes

“…Prostate cancer remains an increasingly common malignancy worldwide. Many advances in drug development have been achieved for the conventional treatments;…”
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An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid by Perrone, Maria Grazia, Miciaccia, Morena, Vitale, Paola, Ferorelli, Savina, Araújo, Cristina da Costa Bernardes, de Almeida, Gabriella Silva, Souza Domingos, Thaisa Francielle, da Silva, Luiz Claudio Rodrigues Pereira, de Pádula, Marcelo, Cabral, Lucio Mendes, Sathler, Plínio Cunha, Bonaccorso, Carmela, Fortuna, Cosimo G., Scilimati, Antonio

“…Cardiovascular diseases (CVDs) account for over 17 million death globally each year, including arterial thrombosis. Platelets are key components in the…”
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Discovery of a Novel Inhibitor of Human Purine Nucleoside Phosphorylase by a Simple Hydrophilic Interaction Liquid Chromatography Enzymatic Assay by Rabuffetti, Marco, Rinaldi, Francesca, Lo Bianco, Alessandra, Speranza, Giovanna, Ubiali, Daniela, Moraes, Marcela Cristina, Rodrigues Pereira da Silva, Luiz Claudio, Massolini, Gabriella, Calleri, Enrica, Lavecchia, Antonio

“…Human purine nucleoside phosphorylase (HsPNP) belongs to the purine salvage pathway of nucleic acids. Genetic deficiency of this enzyme triggers apoptosis of…”
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Vancomycin-loaded nanoparticles against vancomycin intermediate and methicillin resistant Staphylococcus aureus strains by Simon, Alice, Moreira, Marina Lucianeli Araujo, Costa, Isabela Francisca de Jesus Borges, de Sousa, Valeria Pereira, Rodrigues, Carlos Rangel, da Rocha E Lima, Luís Maurício Trambaioli, Sisnande, Tháyna, do Carmo, Flavia Almada, Leal, Ivana Correa Ramos, Dos Santos, Katia Regina Netto, da Silva, Luiz Claudio Rodrigues Pereira, Cabral, Lucio Mendes

“…Bacterial infections represent one of the leading causes of mortality in the world. Among causative pathogens, S. aureus is prominently known as the underlying…”
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Preparation and scale up of extended-release tablets of bromopride by Ferreira, Guilherme Neves, Silva, Marcos Giovani Rodrigues, Fraga, Aline Guerra Manssour, Silva, Luiz Cláudio Rodrigues Pereira da, Lira, Luiz Marcelo, Rodrigues, Carlos Rangel, Castro, Helena Carla, Sousa, Valéria Pereira de, Cabral, Lucio Mendes

“…Reproducibility of the tablet manufacturing process and control of its pharmaceutics properties depends on the optimization of formulation aspects and process…”
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Comparison of in vitro, in vivo, and in silico bioavailability results of different prednisone tablet formulations to assess the feasibility of possible biowaiver by Toehwé, Leonardo Henrique, Da Silva Honorio, Thiago, Rodrigues Pereira da Silva, Luiz Claudio, Da Silva, Thalita Martins, Da Rocha Pitta, Luciana, Deris Prado, Livia, Mendes Cabral, Lucio, Antunes Rocha, Helvécio Vinícius

“…Introduction: The immediate-release solid oral products containing very soluble and permeable drugs are candidates for the biowaiver process. This work aims to…”
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Oral pentamidine-loaded poly(d,l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment by Valle, Isabela Viol, Machado, Monique Etnea, Araújo, Cristina da Costa Bernardes, da Cunha-Junior, Edézio Ferreira, da Silva Pacheco, Juliana, Torres-Santos, Eduardo Caio, da Silva, Luiz Cláudio Rodrigues Pereira, Cabral, Lucio Mendes, do Carmo, Flávia Almada, Sathler, Plínio Cunha

“…Leishmaniasis is a group of diseases caused by a protozoa parasite from one of over 20 Leishmania species. Depending on the tissues infected, these diseases…”
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Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1H-1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells by Costa, Dora C.S., de Almeida, Gabriella Silva, Rabelo, Vitor Won-Held, Cabral, Lucio Mendes, Sathler, Plínio Cunha, Alvarez Abreu, Paula, Ferreira, Vitor Francisco, Cláudio Rodrigues Pereira da Silva, Luiz, da Silva, Fernando de C.

“…Naphthoquinones and 1,2,3-triazoles are structural pharmacophore that is known to impart several cancer cells. This work shows a synthetic methodology to…”
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Development of rivaroxaban microemulsion-based hydrogel for transdermal treatment and prevention of venous thromboembolism by Araújo, Cristina da Costa Bernardes, Simon, Alice, Honório, Thiago da Silva, da Silva, Silvia Valéria Cruz, Valle, Isabella Mourão Machado, da Silva, Luiz Cláudio Rodrigues Pereira, Rodrigues, Carlos Rangel, de Sousa, Valeria Pereira, Cabral, Lucio Mendes, Sathler, Plínio Cunha, do Carmo, Flávia Almada

“…[Display omitted] •Novel microemulsion-based hydrogel containing rivaroxaban (PME-1b) was developed.•PME-1b presented good release profile, stability and pH…”
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Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability by Pati, Maria Laura, Vitale, Paola, Ferorelli, Savina, Iaselli, Mariaclara, Miciaccia, Morena, Boccarelli, Angelina, Di Mauro, Giuseppe Davide, Fortuna, Cosimo G., Souza Domingos, Thaisa Francielle, Rodrigues Pereira da Silva, Luiz Cláudio, de Pádula, Marcelo, Cabral, Lucio Mendes, Sathler, Plínio Cunha, Vacca, Angelo, Scilimati, Antonio, Perrone, Maria Grazia

“…A set of novel diarylisoxazoles has been projected using mofezolac (1) as a lead compound to investigate structure-inhibitory activity relationships of new…”
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Development and Characterization of Nisin Nanoparticles as Potential Alternative for the Recurrent Vaginal Candidiasis Treatment by de Abreu, Letícia Coli Louvisse, Todaro, Valerio, Sathler, Plinio Cunha, da Silva, Luiz Cláudio Rodrigues Pereira, do Carmo, Flávia Almada, Costa, Cleonice Marques, Toma, Helena Keiko, Castro, Helena Carla, Rodrigues, Carlos Rangel, de Sousa, Valeria Pereira, Cabral, Lucio Mendes

“…The aim of this work was the development and characterization of nisin-loaded nanoparticles and the evaluation of its potential antifungal activity…”
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In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N-acylhydrazone derivatives and development of nanosystems: determination of novel NAH derivatives antiplatelet and nanotechnological approach by Sathler, Plínio Cunha, Lourenço, André Luiz, Rodrigues, Carlos Rangel, da Silva, Luiz Cláudio Rodrigues Pereira, Cabral, Lucio Mendes, Jordão, Alessandro Kappel, Cunha, Anna Cláudia, Vieira, Maria Cecília Bastos, Ferreira, Vitor Francisco, Carvalho-Pinto, Carla Eponina, Kang, Hye Chung, Castro, Helena Carla

“…Cardiovascular diseases are the most frequent cause of morbidity and mortality worldwide. Among the most important cardiovascular diseases are atherothrombosis…”
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Evaluation of the effectiveness of the notification process in the area of health products by Colli, Luciana Ferreira Mattos, da Silva, Luiz Cláudio Rodrigues Pereira, de Sousa, Valeria Pereira, de Padula, Marcelo, Cabral, Lucio Mendes

“…•The adequacy of the company that makes notifications of techno vigilance to the good manufacturing practices in force and the registration of the product in…”
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Drug Delivery to the Brain: Recent Advances and Unmet Challenges by Bhunia, Sukanya, Kolishetti, Nagesh, Vashist, Arti, Yndart Arias, Adriana, Brooks, Deborah, Nair, Madhavan

“…Brain cancers and neurodegenerative diseases are on the rise, treatments for central nervous system (CNS) diseases remain limited. Despite the significant…”
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Development of inhaled formulation of modified clofazimine as an alternative to treatment of tuberculosis by de Castro, Renata Ribeiro, Todaro, Valério, da Silva, Luiz Claudio Rodrigues Pereira, Simon, Alice, do Carmo, Flavia Almada, de Sousa, Valeria Pereira, Rodrigues, Carlos Rangel, Sarmento, Bruno, Healy, Anne Marie, Cabral, Lucio Mendes

“…Inhalation drug delivery provides a possible useful alternative to oral drug delivery in the treatment of tuberculosis (TB). This work evaluated inclusion…”
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Crystalline forms of nonprotein drugs filed in Brazil from 1995-2005 by Lira, Luiz Marcelo, da Silva, Luiz Cláudio Rodrigues Pereira, Ribeiro, Antônio J, Veiga, Francisco, Rodrigues, Carlos Rangel, do Carmo, Flávia Almada, de Sousa, Valéria Pereira, Cabral, Lúcio Mendes

“…In the present study, we evaluated 457 patent applications filed for crystalline forms of nonprotein drugs during the period 1995-2005 in Brazil. Online…”
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In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N -acylhydrazone derivatives and development of nanosystems by Sathler, Plínio Cunha, Lourenço, André Luiz, Rodrigues, Carlos Rangel, da Silva, Luiz Cláudio Rodrigues Pereira, Cabral, Lucio Mendes, Jordão, Alessandro Kappel, Cunha, Anna Cláudia, Vieira, Maria Cecília Bastos, Ferreira, Vitor Francisco, Carvalho-Pinto, Carla Eponina, Kang, Hye Chung, Castro, Helena Carla

“…Abstract Background Cardiovascular diseases are the most frequent cause of morbidity and mortality worldwide. Among the most important cardiovascular diseases…”
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